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Electronic health records (EHRs) provide a powerful basis for predicting the onset of health outcomes. Yet EHRs primarily capture in-clinic events and miss aspects of daily behavior and lifestyle containing rich health information. Consumer…

To facilitate healthcare delivery, language models (LMs) have significant potential for clinical prediction tasks using electronic health records (EHRs). However, in these high-stakes applications, unreliable decisions can result in high…

Computation and Language · Computer Science 2024-11-07 Zizhang Chen , Peizhao Li , Xiaomeng Dong , Pengyu Hong

Structured prediction models aim at solving a type of problem where the output is a complex structure, rather than a single variable. Performing knowledge distillation for such models is not trivial due to their exponentially large output…

Machine Learning · Computer Science 2022-03-10 Wenye Lin , Yangming Li , Lemao Liu , Shuming Shi , Hai-tao Zheng

Predicting the health risks of patients using Electronic Health Records (EHR) has attracted considerable attention in recent years, especially with the development of deep learning techniques. Health risk refers to the probability of the…

Machine Learning · Computer Science 2022-11-15 Yuxi Liu , Shaowen Qin , Antonio Jimeno Yepes , Wei Shao , Zhenhao Zhang , Flora D. Salim

Heart failure (HF) is a major cause of mortality. Accurately monitoring HF progress and adjust therapies are critical for improving patient outcomes. An experienced cardiologist can make accurate HF stage diagnoses based on combination of…

Machine Learning · Computer Science 2021-03-23 Shuyu Lu , Ruoyu Chen , Wei Wei , Xinghua Lu

In this study, we investigated the application of bio-inspired optimization algorithms, including Genetic Algorithm, Particle Swarm Optimization, and Whale Optimization Algorithm, for feature selection in chronic disease prediction. The…

Neural and Evolutionary Computing · Computer Science 2024-01-12 Abeer Dyoub , Ivan Letteri

Consider a situation where a new patient arrives in the Intensive Care Unit (ICU) and is monitored by multiple sensors. We wish to assess relevant unmeasured physiological variables (e.g., cardiac contractility and output and vascular…

Machine Learning · Statistics 2022-02-17 Ron Teichner , Ron Meir , Danny Eitan

Electronic health record (EHR)-linked biobank data hold tremendous promise for large-scale discoveries via genome-wide association study (GWAS) on diverse phenotypic traits and biomarkers routinely captured in the EHR. However,…

Applications · Statistics 2026-04-14 Xingran Chen , Cheng-Han Yang , Zhenke Wu , Bhramar Mukherjee

The paper proposes and investigates an approach for surrogate-assisted performance prediction of data-driven knowledge discovery algorithms. The approach is based on the identification of surrogate models for prediction of the target…

Machine Learning · Computer Science 2022-01-25 Anastasia A. Funkner , Aleksey N. Yakovlev , Sergey V. Kovalchuk

Conformal prediction has recently emerged as a promising strategy for quantifying the uncertainty of a predictive model; these algorithms modify the model to output sets of labels that are guaranteed to contain the true label with high…

Machine Learning · Computer Science 2025-03-11 Botong Zhang , Shuo Li , Osbert Bastani

The use of Electronic Health Records (EHRs) has increased dramatically in the past 15 years, as, it is considered an important source of managing data od patients. The EHRs are primary sources of disease diagnosis and demographic data of…

Machine Learning · Computer Science 2024-04-02 Bushra F. Alsaqer , Alaa F. Alsaqer , Amna Asif

Regular documentation of progress notes is one of the main contributors to clinician burden. The abundance of structured chart information in medical records further exacerbates the burden, however, it also presents an opportunity to…

Computation and Language · Computer Science 2024-10-18 Sarvesh Soni , Dina Demner-Fushman

In a data-scarce field such as healthcare, where models often deliver predictions on patients with rare conditions, the ability to measure the uncertainty of a model's prediction could potentially lead to improved effectiveness of decision…

Machine Learning · Statistics 2020-05-26 Lotta Meijerink , Giovanni Cinà , Michele Tonutti

Large language models (LLMs) show promise for clinical reasoning and decision support, but evaluation in realistic, electronic health record-congruent settings remains limited. Existing benchmarks often rely on static datasets or…

Computation and Language · Computer Science 2026-05-29 Valentina Bui Muti , Eugénie Dulout , Ziquan Fu

Clinical trials provide essential guidance for practicing Evidence-Based Medicine, though often accompanying with unendurable costs and risks. To optimize the design of clinical trials, we introduce a novel Clinical Trial Result Prediction…

Computation and Language · Computer Science 2020-10-13 Qiao Jin , Chuanqi Tan , Mosha Chen , Xiaozhong Liu , Songfang Huang

Early prediction of mortality and length of stay(LOS) of a patient is vital for saving a patient's life and management of hospital resources. Availability of electronic health records(EHR) makes a huge impact on the healthcare domain and…

Machine Learning · Computer Science 2020-12-01 Batuhan Bardak , Mehmet Tan

Quantifying uncertainty in clinical predictions is critical for high-stakes diagnosis tasks. Conformal prediction offers a principled approach by providing prediction sets with theoretical coverage guarantees. However, in practice, patient…

Machine Learning · Computer Science 2026-05-01 Arjun Chatterjee , Sayeed Sajjad Razin , John Wu , Siddhartha Laghuvarapu , Jathurshan Pradeepkumar , Jimeng Sun

Sensor monitoring networks and advances in big data analytics have guided the reliability engineering landscape to a new era of big machinery data. Low-cost sensors, along with the evolution of the internet of things and industry 4.0, have…

Machine Learning · Statistics 2021-10-11 Sergio Cofre-Martel , Enrique Lopez Droguett , Mohammad Modarres

A crucial step in cohort studies is to extract the required cohort from one or more study datasets. This step is time-consuming, especially when a researcher is presented with a dataset that they have not previously worked with. When the…

Machine Learning · Computer Science 2024-12-17 Purity Mugambi , Alexandra Meliou , Madalina Fiterau

We present a machine learning pipeline and model that uses the entire uncurated EHR for prediction of in-hospital mortality at arbitrary time intervals, using all available chart, lab and output events, without the need for pre-processing…

Machine Learning · Computer Science 2019-09-18 Jacob Deasy , Pietro Liò , Ari Ercole