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Computationally efficient surrogates for parametrized physical models play a crucial role in science and engineering. Operator learning provides data-driven surrogates that map between function spaces. However, instead of full-field…

Machine Learning · Computer Science 2024-12-31 Daniel Zhengyu Huang , Nicholas H. Nelsen , Margaret Trautner

Neural surrogates promise large speedups over classical solvers for physical dynamics but fail silently at sharp dynamical events such as shocks, fronts, and contact. We present hybrid neural world models for physical dynamics: a recipe for…

Machine Learning · Computer Science 2026-05-28 Pranav Lakshmanan , Paras Chopra

Geometry optimization is an important part of both computational materials and surface science because it is the path to finding ground state atomic structures and reaction pathways. These properties are used in the estimation of…

Materials Science · Physics 2021-07-07 Yilin Yang , Omar A. Jimenez-Negron , John R. Kitchin

In this paper, we present a surrogate-based multiscale approach to model constant strain-rate and creep experiments on unidirectional thermoplastic composites under off-axis loading. In previous contributions, these experiments were modeled…

Numerical Analysis · Mathematics 2025-01-20 M. A. Maia , I. B. C. M. Rocha , D. Kovačević , F. P. van der Meer

Temperature is a fundamental regulator of chemical and biochemical kinetics, yet capturing nonlinear thermal effects directly from experimental data remains a major challenge due to limited throughput and model flexibility. Recent advances…

Quantitative Methods · Quantitative Biology 2025-12-23 Mamoru Saita , Yutaka Hori

Neural operators have emerged as powerful tools for learning solution operators of partial differential equations. However, in time-dependent problems, standard training strategies such as teacher forcing introduce a mismatch between…

Machine Learning · Computer Science 2025-05-28 Zaijun Ye , Chen-Song Zhang , Wansheng Wang

The high computational cost associated with solving for detailed chemistry poses a significant challenge for predictive computational fluid dynamics (CFD) simulations of turbulent reacting flows. These models often require solving a system…

Computational Physics · Physics 2024-03-05 Tadbhagya Kumar , Anuj Kumar , Pinaki Pal

High-fidelity simulations of laser welding capture complex thermo-fluid phenomena, including phase change, free-surface deformation, and keyhole dynamics, however their computational cost limits large-scale process exploration and real-time…

Machine Learning · Computer Science 2026-04-01 Alix Benoit , Toni Ivas , Mateusz Papierz , Asel Sagingalieva , Alexey Melnikov , Elia Iseli

Quantum mechanics based ab-initio molecular dynamics (MD) simulation schemes offer an accurate and direct means to monitor the time-evolution of materials. Nevertheless, the expensive and repetitive energy and force computations required in…

Materials Science · Physics 2014-10-14 Venkatesh Botu , Rampi Ramprasad

Recent advances in scientific machine learning (SciML) have enabled neural operators (NOs) to serve as powerful surrogates for modeling the dynamic evolution of physical systems governed by partial differential equations (PDEs). While…

Machine Learning · Computer Science 2026-02-18 Siying Ma , Mehrdad M. Zadeh , Mauricio Soroco , Wuyang Chen , Jiguo Cao , Vijay Ganesh

Non-adiabatic molecular dynamics (NAMD) simulations have become an indispensable tool for investigating excited-state dynamics in solids. In this work, we propose a general framework, N$^2$AMD which employs an E(3)-equivariant deep neural…

Recent advances in deep learning have allowed neural networks (NNs) to successfully replace traditional numerical solvers in many applications, thus enabling impressive computing gains. One such application is time domain simulation, which…

Machine Learning · Computer Science 2021-12-09 Samuel Chevalier , Jochen Stiasny , Spyros Chatzivasileiadis

The accurate incorporation of nuclear quantum effects in large-scale molecular dynamics (MD) simulations remains a significant challenge. Recently, we combined constrained nuclear-electronic orbital (CNEO) theory with classical MD and…

Chemical Physics · Physics 2023-01-11 Zehua Chen , Yang Yang

Self-supervised pretraining from static structures of drug-like compounds and proteins enable powerful learned feature representations. Learned features demonstrate state of the art performance on a range of predictive tasks including…

Biomolecules · Quantitative Biology 2025-09-12 Derek Jones , Yue Yang , Felice C. Lightstone , Niema Moshiri , Jonathan E. Allen , Tajana S. Rosing

Mechanistic modeling provides a biophysically grounded framework for studying the spread of pathological tau protein in tauopathies like Alzheimer's disease. Existing approaches typically model tau propagation as a diffusive process on the…

Computational Engineering, Finance, and Science · Computer Science 2026-03-18 Nuutti Barron , Heng Rao , Urmi Saha , Yu Gu , Zhenghao Liu , Ge Yu , Defu Yang , Ashish Raj , Minghan Chen

Predictive simulations are essential for applications ranging from weather forecasting to material design. The veracity of these simulations hinges on their capacity to capture the effective system dynamics. Massively parallel simulations…

Background: Traumatic brain injury modeling requires integrating volumetric neuroimaging, demographic parameters, and acquisition metadata. Finite element solvers are too computationally expensive for clinical settings. Neural operators…

Machine Learning · Computer Science 2026-04-27 Anusha Agarwal , Dibakar Roy Sarkar , Somdatta Goswami

Data-driven convective parameterization aims to accurately represent convective adjustments to large-scale forcings in a computationally economic manner. While previous studies have demonstrated success using various model architectures,…

Atmospheric and Oceanic Physics · Physics 2025-06-02 Qiyu Song , Zhiming Kuang

This paper introduces Stress-Aware Learning, a resilient neural training paradigm in which deep neural networks dynamically adjust their optimization behavior - whether under stable training regimes or in settings with uncertain dynamics -…

Machine Learning · Computer Science 2025-08-04 Ashkan Shakarami , Yousef Yeganeh , Azade Farshad , Lorenzo Nicole , Stefano Ghidoni , Nassir Navab

Surrogate models for partial-differential equations are widely used in the design of meta-materials to rapidly evaluate the behavior of composable components. However, the training cost of accurate surrogates by machine learning can rapidly…

Machine Learning · Computer Science 2020-11-04 Raphaël Pestourie , Youssef Mroueh , Thanh V. Nguyen , Payel Das , Steven G. Johnson