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We present a fully automated, anatomically guided deep learning pipeline for prostate cancer (PCa) risk stratification using routine MRI. The pipeline integrates three key components: an nnU-Net module for segmenting the prostate gland and…

Mosaic Flow is a novel domain decomposition method designed to scale physics-informed neural PDE solvers to large domains. Its unique approach leverages pre-trained networks on small domains to solve partial differential equations on large…

Machine Learning · Computer Science 2023-08-29 Arthur Feeney , Zitong Li , Ramin Bostanabad , Aparna Chandramowlishwaran

Deep learning has shown unprecedented success in a variety of applications, such as computer vision and medical image analysis. However, there is still potential to improve segmentation in multimodal images by embedding prior knowledge via…

Image and Video Processing · Electrical Eng. & Systems 2019-10-24 Kibrom Berihu Girum , Gilles Créhange , Raabid Hussain , Paul Michael Walker , Alain Lalande

Inverse problems of partial differential equations are ubiquitous across various scientific disciplines and can be formulated as statistical inference problems using Bayes' theorem. To address large-scale problems, it is crucial to develop…

Numerical Analysis · Mathematics 2025-12-23 Yang Zhao , Haoyu Lu , Junxiong Jia , Tao Zhou

Differential cross section measurements are the currency of scientific exchange in particle and nuclear physics. A key challenge for these analyses is the correction for detector distortions, known as deconvolution or unfolding. Binned…

High Energy Physics - Phenomenology · Physics 2025-09-09 Fernando Torales Acosta , Jay Chan , Krish Desai , Vinicius Mikuni , Benjamin Nachman , Jingjing Pan , Francesco Rubbo

Sparse deep learning aims to address the challenge of huge storage consumption by deep neural networks, and to recover the sparse structure of target functions. Although tremendous empirical successes have been achieved, most sparse deep…

Machine Learning · Statistics 2020-11-17 Jincheng Bai , Qifan Song , Guang Cheng

Object pose estimation is a fundamental problem in robotics and computer vision, yet it remains challenging due to partial observability, occlusions, and object symmetries, which inevitably lead to pose ambiguity and multiple hypotheses…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Yufeng Jin , Niklas Funk , Vignesh Prasad , Zechu Li , Mathias Franzius , Jan Peters , Georgia Chalvatzaki

With the development of deep convolutional neural networks, medical image segmentation has achieved a series of breakthroughs in recent years. However, the high-performance convolutional neural networks always mean numerous parameters and…

Computer Vision and Pattern Recognition · Computer Science 2022-08-30 Wenxuan Zou , Muyi Sun

The assessment of imaging biomarkers is critical for advancing precision medicine and improving disease characterization. Despite the availability of methods to derive disease heterogeneity metrics in imaging studies, a robust framework for…

Variational Bayesian phylogenetic inference (VBPI) provides a promising general variational framework for efficient estimation of phylogenetic posteriors. However, the current diagonal Lognormal branch length approximation would…

Populations and Evolution · Quantitative Biology 2020-12-02 Cheng Zhang

Automatic segmentation of the prostate cancer from the multi-modal magnetic resonance images is of critical importance for the initial staging and prognosis of patients. However, how to use the multi-modal image features more efficiently is…

Image and Video Processing · Electrical Eng. & Systems 2020-11-10 Guokai Zhang , Xiaoang Shen , Ye Luo , Jihao Luo , Zeju Wang , Weigang Wang , Binghui Zhao , Jianwei Lu

Many modern applications of Bayesian inference, such as in cosmology, are based on complicated forward models with high-dimensional parameter spaces. This considerably limits the sampling of posterior distributions conditioned on observed…

Instrumentation and Methods for Astrophysics · Physics 2024-09-17 Marco Raveri , Cyrille Doux , Shivam Pandey

Normalizing flows have emerged as an important family of deep neural networks for modelling complex probability distributions. In this note, we revisit their coupling and autoregressive transformation layers as probabilistic graphical…

Machine Learning · Computer Science 2020-06-05 Antoine Wehenkel , Gilles Louppe

We introduce the Flow Stochastic Segmentation Network (Flow-SSN), a generative segmentation model family featuring discrete-time autoregressive and modern continuous-time flow variants. We prove fundamental limitations of the low-rank…

Computer Vision and Pattern Recognition · Computer Science 2025-07-28 Fabio De Sousa Ribeiro , Omar Todd , Charles Jones , Avinash Kori , Raghav Mehta , Ben Glocker

Recently, there has been a surge of interest in incorporating neural networks into particle filters, e.g. differentiable particle filters, to perform joint sequential state estimation and model learning for non-linear non-Gaussian…

Machine Learning · Computer Science 2025-01-07 Xiongjie Chen , Yunpeng Li

The Normalizing Flow (NF) models a general probability density by estimating an invertible transformation applied on samples drawn from a known distribution. We introduce a new type of NF, called Deep Diffeomorphic Normalizing Flow (DDNF).…

Machine Learning · Statistics 2018-11-26 Hadi Salman , Payman Yadollahpour , Tom Fletcher , Kayhan Batmanghelich

Bayes' rule naturally allows for inference refinement in a streaming fashion, without the need to recompute posteriors from scratch whenever new data arrives. In principle, Bayesian streaming is straightforward: we update our prior with the…

Machine Learning · Computer Science 2024-11-12 Tiago da Silva , Daniel Augusto de Souza , Diego Mesquita

Deep learning-based computer-aided diagnosis is gradually deployed to review and analyze medical images. However, this paradigm is restricted in real-world clinical applications due to the poor robustness and generalization. The issue is…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yurong Chen

Deep learning (DL) models for segmenting various anatomical structures have achieved great success via a static DL model that is trained in a single source domain. Yet, the static DL model is likely to perform poorly in a continually…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Xiaofeng Liu , Helen A. Shih , Fangxu Xing , Emiliano Santarnecchi , Georges El Fakhri , Jonghye Woo

Normalizing flows (NFs) have become a prominent method for deep generative models that allow for an analytic probability density estimation and efficient synthesis. However, a flow-based network is considered to be inefficient in parameter…

Machine Learning · Computer Science 2020-10-26 Sang-gil Lee , Sungwon Kim , Sungroh Yoon