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Synthetic tabular data is increasingly used in privacy-sensitive domains such as health care, but existing generative models often fail to preserve inter-attribute relationships. In particular, functional dependencies (FDs) and logical…

Machine Learning · Computer Science 2025-07-28 Chaithra Umesh , Kristian Schultz , Manjunath Mahendra , Saptarshi Bej , Olaf Wolkenhauer

Procuring expressive molecular representations underpins AI-driven molecule design and scientific discovery. The research mainly focuses on atom-level homogeneous molecular graphs, ignoring the rich information in subgraphs or motifs.…

Quantitative Methods · Quantitative Biology 2023-01-10 Fang Wu , Dragomir Radev , Stan Z. Li

Accurately modeling multi-class cell topology is crucial in digital pathology, as it provides critical insights into tissue structure and pathology. The synthetic generation of cell topology enables realistic simulations of complex tissue…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Meilong Xu , Saumya Gupta , Xiaoling Hu , Chen Li , Shahira Abousamra , Dimitris Samaras , Prateek Prasanna , Chao Chen

Graph Neural Networks (GNNs) have demonstrated impressive performance in learning representations from graph-structured data. However, their message-passing mechanism inherently relies on the assumption of label consistency among connected…

Machine Learning · Computer Science 2026-04-28 Taihua Xu , Genhao Tian , Jicong Fan , Xibei Yang , Qinghua Zhang , Yun Cui

This work explores the challenging problem of molecule design by framing it as a conditional generative modeling task, where target biological properties or desired chemical constraints serve as conditioning variables. We propose the Latent…

Topological phase transitions, which do not adhere to Landau's phenomenological model (i.e. a spontaneous symmetry breaking process and vanishing local order parameters) have been actively researched in condensed matter physics. Machine…

Mesoscale and Nanoscale Physics · Physics 2021-03-03 Alexander Kerr , Geo Jose , Colin Riggert , Kieran Mullen

Metal-organic frameworks (MOFs) are highly promising for carbon capture, yet navigating their vast design space remains challenging. Recent deep generative models enable de novo MOF design but primarily act as feed-forward structure…

Machine Learning · Computer Science 2026-04-16 Chaoran Zhang , Guangyao Li , Dongxu Ji

We study 3D chaotic dynamics through an analysis of transport in a granular flow in a half-full spherical tumbler rotated sequentially about two orthogonal axes (a bi-axial "blinking" tumbler). The flow is essentially quasi-2D in any…

Dynamical Systems · Mathematics 2014-07-02 Ivan C. Christov , Richard M. Lueptow , Julio M. Ottino , Rob Sturman

Developing an effective molecular generation framework even with a limited number of molecules is often important for its practical deployment, e.g., drug discovery, since acquiring task-related molecular data requires expensive and…

Machine Learning · Computer Science 2024-07-17 Seojin Kim , Jaehyun Nam , Sihyun Yu , Younghoon Shin , Jinwoo Shin

Topology diagrams are widely seen in power system applications, but their automatic generation is often easier said than done. When facing power transmission systems with strongly-meshed structures, existing approaches can hardly produce…

Systems and Control · Electrical Eng. & Systems 2023-03-21 Jingyu Wang , Jinfu Chen , Dongyuan Shi , Xianzhong Duan

Structure-based drug design (SBDD) aims to efficiently discover high-affinity ligands within vast chemical spaces. However, current generative models struggle with objective misalignment and rigid sampling budgets. We present MolFORM, a…

Computational Engineering, Finance, and Science · Computer Science 2026-02-26 Daiheng Zhang , Zhao Zhang

With the proliferation of intelligent mobile devices in wireless device-to-device (D2D) networks, decentralized federated learning (DFL) has attracted significant interest. Compared to centralized federated learning (CFL), DFL mitigates the…

Machine Learning · Computer Science 2024-03-12 Zheshun Wu , Zenglin Xu , Dun Zeng , Junfan Li , Jie Liu

We introduce HyperDiffusionFields (HyDiF), a framework that models 3D molecular conformers as continuous fields rather than discrete atomic coordinates or graphs. At the core of our approach is the Molecular Directional Field (MDF), a…

Machine Learning · Computer Science 2025-10-22 Sudarshan Babu , Phillip Lo , Xiao Zhang , Aadi Srivastava , Ali Davariashtiyani , Jason Perera , Michael Maire , Aly A. Khan

Optical flow estimation is a fundamental and long-standing visual task. In this work, we present a novel method, dubbed HMAFlow, to improve optical flow estimation in challenging scenes, particularly those involving small objects. The…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Dianbo Ma , Kousuke Imamura , Ziyan Gao , Xiangjie Wang , Satoshi Yamane

Time series generation is critical for a wide range of applications, which greatly supports downstream analytical and decision-making tasks. However, the inherent temporal heterogeneous induced by localized perturbations present significant…

Machine Learning · Computer Science 2025-11-19 Jintao Zhang , Mingyue Cheng , Zirui Liu , Xianquan Wang , Yitong Zhou , Qi Liu

Climate events arise from intricate, multivariate dynamics governed by global-scale drivers, profoundly impacting food, energy, and infrastructure. Yet, accurate weather prediction remains elusive due to physical processes unfolding across…

Machine Learning · Computer Science 2025-10-31 Thomas Bailie , S. Karthik Mukkavilli , Varvara Vetrova , Yun Sing Koh

Estimating three-dimensional conformations of a molecular graph allows insight into the molecule's biological and chemical functions. Fast generation of valid conformations is thus central to molecular modeling. Recent advances in…

Machine Learning · Computer Science 2025-02-18 Sohil Atul Shah , Vladlen Koltun

High Definition (HD) maps are maps with precise definitions of road lanes with rich semantics of the traffic rules. They are critical for several key stages in an autonomous driving system, including motion forecasting and planning.…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Lu Mi , Hang Zhao , Charlie Nash , Xiaohan Jin , Jiyang Gao , Chen Sun , Cordelia Schmid , Nir Shavit , Yuning Chai , Dragomir Anguelov

Multivariate time series anomaly detection has become an active area of research in recent years, with Deep Learning models outperforming previous approaches on benchmark datasets. Among reconstruction-based models, most previous work has…

Machine Learning · Computer Science 2022-02-28 Cristian Challu , Peihong Jiang , Ying Nian Wu , Laurent Callot

Generating stable molecular conformations typically forces a tradeoff between the physical realism of energy-based relaxation and the sampling efficiency of data-driven generative models. While machine learning force fields (MLFFs) can…