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We present the Analytical Memory Model with Pipelines (AMMP) of the Performance Prediction Toolkit (PPT). PPT-AMMP takes high-level source code and hardware architecture parameters as input, predicts runtime of that code on the target…

Performance · Computer Science 2020-11-16 Gopinath Chennupati , Nandakishore Santhi , Phill Romero , Stephan Eidenbenz

Machine learning (ML) models rely heavily on consistent and accurate performance metrics to evaluate and compare their effectiveness. However, existing libraries often suffer from fragmentation, inconsistent implementations, and…

This study employed an artificial intelligence-enhanced molecular simulation framework to enable efficient Path Integral Molecular Dynamics (PIMD) simulations. Owing to its modular architecture and high-throughput capabilities, the…

Chemical Physics · Physics 2025-04-01 Cheng Fan , Maodong Li , Sihao Yuan , Zhaoxin Xie , Dechin Chen , Yi Isaac Yang , Yi Qin Gao

Recently, Graph Transformer (GT) models have been widely used in the task of Molecular Property Prediction (MPP) due to their high reliability in characterizing the latent relationship among graph nodes (i.e., the atoms in a molecule).…

Machine Learning · Computer Science 2023-10-12 Wentao Yu , Shuo Chen , Chen Gong , Gang Niu , Masashi Sugiyama

Accurate molecular geometries are a prerequisite for reliable quantum-chemical predictions, yet density functional theory (DFT) optimization remains a major bottleneck for high-throughput molecular screening. Here we present GeoOpt-Net, a…

Chemical Physics · Physics 2026-02-02 Chengchun Liu , Wendi Cai , Boxuan Zhao , Fanyang Mo

The language-guided robot grasping task requires a robot agent to integrate multimodal information from both visual and linguistic inputs to predict actions for target-driven grasping. While recent approaches utilizing Multimodal Large…

Robotics · Computer Science 2025-02-10 Houjian Yu , Mingen Li , Alireza Rezazadeh , Yang Yang , Changhyun Choi

Computational and machine learning approaches to model the conformational landscape of macrocyclic peptides have the potential to enable rational design and optimization. However, accurate, fast, and scalable methods for modeling macrocycle…

Biomolecules · Quantitative Biology 2024-08-12 Colin A. Grambow , Hayley Weir , Christian N. Cunningham , Tommaso Biancalani , Kangway V. Chuang

Alloy discovery is constrained by vast compositional spaces, competing objectives, and prohibitive experimental costs. Although simulations and machine learning have each accelerated parts of this process, unifying scientific knowledge,…

Speech Large Language Models (SLLMs) enable high-level emotion reasoning but often produce ungrounded, text-biased judgments without verifiable acoustic evidence. In contrast, self-supervised speech encoders such as WavLM provide strong…

Machine Learning · Computer Science 2026-02-16 Esther Sun , Bo-Hao Su , Abinay Reddy Naini , Shinji Watanabe , Carlos Busso

Large-scale, standardized datasets for Advanced Persistent Threat (APT) research are scarce, and inconsistent actor aliases and redundant samples hinder reproducibility. This paper presents APT-ClaritySet and its construction pipeline that…

Cryptography and Security · Computer Science 2025-12-18 Zhenhao Yin , Hanbing Yan , Huishu Lu , Jing Xiong , Xiangyu Li , Rui Mei , Tianning Zang

Hydrogen atom transfer (HAT) reactions are essential in many biological processes, such as radical migration in damaged proteins, but their mechanistic pathways remain incompletely understood. Simulating HAT is challenging due to the need…

Machine Learning · Computer Science 2025-11-25 Marlen Neubert , Patrick Reiser , Frauke Gräter , Pascal Friederich

Machine learning (ML) accelerates the exploration of material properties and their links to the structure of the underlying molecules. In previous work [J. Shi, M. J. Quevillon, P. H. A. Valen\c{c}a, and J. K. Whitmer, \textit{ACS Appl.…

Soft Condensed Matter · Physics 2023-01-06 Jiale Shi , Fahed Albreiki , Yamil J. Colón , Samanvaya Srivastava , Jonathan K. Whitmer

While imitation learning has shown impressive results in single-task robot manipulation, scaling it to multi-task settings remains a fundamental challenge due to issues such as suboptimal demonstrations, trajectory noise, and behavioral…

Robotics · Computer Science 2025-12-23 Yihang Zhu , Weiqing Wang , Shijie Wu , Ye Shi , Jingya Wang

Dopants can tune the performance of MoS2 in various applications, but use of molecular dynamics simulations for doped MoS2 materials discovery is limited by the lack of multi-dopant interatomic potentials. Universal machine learning…

Materials Science · Physics 2026-03-02 Abrar Faiyad , Ashlie Martini

The predictive accuracy of Machine Learning (ML) models of molecular properties depends on the choice of the molecular representation. Based on the postulates of quantum mechanics, we introduce a hierarchy of representations which meet…

Chemical Physics · Physics 2016-11-23 Bing Huang , O. Anatole von Lilienfeld

We present an accurate machine learning (ML) model for atomistic simulations of carbon, constructed using the Gaussian approximation potential (GAP) methodology. The potential, named GAP-20, describes the properties of the bulk crystalline…

Computational Physics · Physics 2020-08-26 Patrick Rowe , Volker L Deringer , Piero Gasparotto , Gábor Csányi , Angelos Michaelides

Recent advancements in computational chemistry have leveraged the power of trans-former-based language models, such as MoLFormer, pre-trained using a vast amount of simplified molecular-input line-entry system (SMILES) sequences, to…

Biomolecules · Quantitative Biology 2024-11-05 Tianhao Peng , Yuchen Li , Xuhong Li , Jiang Bian , Zeke Xie , Ning Sui , Shahid Mumtaz , Yanwu Xu , Linghe Kong , Haoyi Xiong

Retrosynthesis analysis is pivotal yet challenging in drug discovery and organic chemistry. Despite the proliferation of computational tools over the past decade, AI-based systems often fall short in generalizing across diverse reaction…

Machine Learning · Computer Science 2024-08-21 Yifei Yang , Runhan Shi , Zuchao Li , Shu Jiang , Bao-Liang Lu , Yang Yang , Hai Zhao

From the relative scarcity of training data to the lack of standardized benchmarks, the development of foundation models for polymers face significant and multi-faceted challenges. At the core, many of these issues are tied directly to the…

Materials discovery relies on high-throughput, high-fidelity simulation techniques such as Density Functional Theory (DFT), which require years of training, extensive parameter fine-tuning and systematic error handling. To address these…

Artificial Intelligence · Computer Science 2025-07-22 Ziqi Wang , Hongshuo Huang , Hancheng Zhao , Changwen Xu , Shang Zhu , Jan Janssen , Venkatasubramanian Viswanathan
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