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We propose a new methodology for selecting and ranking covariates associated with a variable of interest in a context of high-dimensional data under dependence but few observations. The methodology successively intertwines the clustering of…

Multi-regional interaction among neuronal populations underlies the brain's processing of rich sensory information in our daily lives. Recent neuroscience and neuroimaging studies have increasingly used naturalistic stimuli and experimental…

Neurons and Cognition · Quantitative Biology 2021-06-08 Yu Takagi , Laurence T. Hunt , Ryu Ohata , Hiroshi Imamizu , Jun-ichiro Hirayama

Imaging and hyperspectral data analysis is central to progress across biology, medicine, chemistry, and physics. The core challenge lies in converting high-resolution or high-dimensional datasets into interpretable representations that…

Image and Video Processing · Electrical Eng. & Systems 2025-12-29 Kamyar Barakati , Yu Liu , Utkarsh Pratiush , Boris N. Slautin , Sergei V. Kalinin

While deep learning holds great promise for disease diagnosis and prognosis in cardiac magnetic resonance imaging, its progress is often constrained by highly imbalanced and biased training datasets. To address this issue, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Grzegorz Skorupko , Richard Osuala , Zuzanna Szafranowska , Kaisar Kushibar , Vien Ngoc Dang , Nay Aung , Steffen E Petersen , Karim Lekadir , Polyxeni Gkontra

Multi-view (or -modality) representation learning aims to understand the relationships between different view representations. Existing methods disentangle multi-view representations into consistent and view-specific representations by…

Computer Vision and Pattern Recognition · Computer Science 2023-08-07 Guanzhou Ke , Yang Yu , Guoqing Chao , Xiaoli Wang , Chenyang Xu , Shengfeng He

Completely randomized experiment is the gold standard for causal inference. When the covariate information for each experimental candidate is available, one typical way is to include them in covariate adjustments for more accurate treatment…

Methodology · Statistics 2025-06-10 Xin Lu , Fan Yang , Yuhao Wang

The interdependence and high dimensionality of multivariate signals present significant challenges for denoising, as conventional univariate methods often struggle to capture the complex interactions between variables. A successful approach…

Machine Learning · Computer Science 2024-07-29 Jaesung Choi , Pilwon Kim

In this work, we address the problem of improvement of robustness of feature representations learned using convolutional neural networks (CNNs) to image deformation. We argue that higher moment statistics of feature distributions could be…

Computer Vision and Pattern Recognition · Computer Science 2017-07-26 Zhun Sun , Mete Ozay , Takayuki Okatani

Large datasets often contain multiple distinct feature sets, or views, that offer complementary information that can be exploited by multi-view learning methods to improve results. We investigate anatomical multi-view data, where each brain…

Quantitative Methods · Quantitative Biology 2024-01-17 Yuxiang Wei , Yuqian Chen , Tengfei Xue , Leo Zekelman , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O' Donnell

Estimating a covariance matrix is central to high-dimensional data analysis. Empirical analyses of high-dimensional biomedical data, including genomics, proteomics, microbiome, and neuroimaging, among others, consistently reveal strong…

Methodology · Statistics 2024-12-05 Yifan Yang , Chixiang Chen , Shuo Chen

With the rapid growth of modern technology, many large-scale biomedical studies have been/are being/will be conducted to collect massive datasets with large volumes of multi-modality imaging, genetic, neurocognitive, and clinical…

Methodology · Statistics 2018-03-07 Farouk S. Nathoo , Linglong Kong , Hongtu Zhu

Instrumental variables (IVs) are extensively used to estimate treatment effects when the treatment and outcome are confounded by unmeasured confounders; however, weak IVs are often encountered in empirical studies and may cause problems.…

Methodology · Statistics 2021-10-19 Siyu Heng , Bo Zhang , Xu Han , Scott A. Lorch , Dylan S. Small

Estimating treatment effects from observational data is paramount in healthcare, education, and economics, but current deep disentanglement-based methods to address selection bias are insufficiently handling irrelevant variables. We…

Machine Learning · Computer Science 2024-08-27 Ahmad Saeed Khan , Erik Schaffernicht , Johannes Andreas Stork

When designing experimental studies with human participants, experimenters must decide how many trials each participant will complete, as well as how many participants to test. Most discussion of statistical power (the ability of a study…

Neurons and Cognition · Quantitative Biology 2021-08-30 Daniel H. Baker , Greta Vilidaite , Freya A. Lygo , Anika K. Smith , Tessa R. Flack , Andre D. Gouws , Timothy J. Andrews

Estimating individual-level treatment effect from observational data is a fundamental problem in causal inference and has attracted increasing attention in the fields of education, healthcare, and public policy.In this work, we concentrate…

Machine Learning · Computer Science 2025-07-10 Hui Meng , Keping Yang , Xuyu Peng , Bo Zheng

Skeleton-based human action recognition has been drawing more interest recently due to its low sensitivity to appearance changes and the accessibility of more skeleton data. However, even the 3D skeletons captured in practice are still…

Computer Vision and Pattern Recognition · Computer Science 2022-09-26 Cunling Bian , Wei Feng , Fanbo Meng , Song Wang

We introduce a new task called Defeasible Visual Entailment (DVE), where the goal is to allow the modification of the entailment relationship between an image premise and a text hypothesis based on an additional update. While this concept…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Yue Zhang , Liqiang Jing , Vibhav Gogate

Feature screening is an important method to reduce the dimension and capture informative variables in ultrahigh-dimensional data analysis. Many methods have been developed for feature screening. These methods, however, are challenged by…

Methodology · Statistics 2019-01-08 Li-Pang Chen

Deep neural networks do not discriminate between spurious and causal patterns, and will only learn the most predictive ones while ignoring the others. This shortcut learning behaviour is detrimental to a network's ability to generalize to…

Machine Learning · Computer Science 2023-01-11 Thomas Duboudin , Emmanuel Dellandréa , Corentin Abgrall , Gilles Hénaff , Liming Chen

In multivariate longitudinal studies, associations between outcomes often exhibit time-varying and individual level heterogeneity, motivating the modeling of correlations as an explicit function of time and covariates. However, most…

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