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Children's health studies support an association between maternal environmental exposures and children's birth outcomes. A common goal is to identify critical windows of susceptibility--periods during gestation with increased association…

Myxobacteria are social bacteria, that can glide in 2D and form counter-propagating, interacting waves. Here we present a novel age-structured, continuous macroscopic model for the movement of myxobacteria. The derivation is based on…

Cell Behavior · Quantitative Biology 2018-04-06 Pierre Degond , Angelika Manhart , Hui Yu

This article develops flexible methodology to study the association between scalar outcomes and functional predictors observed over time, at many instances, in longitudinal studies. We propose a parsimonious modeling framework to study…

Applications · Statistics 2018-01-25 Md Nazmul Islam , Ana-Maria Staicu , Eric van Heugten

Birth weight serves as a fundamental indicator of neonatal health, closely linked to both early medical interventions and long-term developmental risks. Traditional predictive models, often constrained by limited feature selection and…

The infant brain undergoes rapid development in the first few years after birth.Compared to cross-sectional studies, longitudinal studies can depict the trajectories of infants brain development with higher accuracy, statistical power and…

Image and Video Processing · Electrical Eng. & Systems 2024-05-20 Zihao Zhu , Tianli Tao , Yitian Tao , Haowen Deng , Xinyi Cai , Gaofeng Wu , Kaidong Wang , Haifeng Tang , Lixuan Zhu , Zhuoyang Gu , Jiawei Huang , Dinggang Shen , Han Zhang

A frequent challenge encountered with ecological data is how to interpret, analyze, or model data having a high proportion of zeros. Much attention has been given to zero-inflated count data, whereas models for non-negative continuous data…

Methodology · Statistics 2022-05-23 Becky Tang , Henry A Frye , Alan E. Gelfand , John A Silander

Analysis of competing risks data plays an important role in the lifetime data analysis. Recently Feizjavadian and Hashemi (Computational Statistics and Data Analysis, vol. 82, 19-34, 2015) provided a classical inference of a competing risks…

Methodology · Statistics 2021-05-04 Debashis Samanta , Debasis Kundu

In Bayesian inference for mixture models with an unknown number of components, a finite mixture model is usually employed that assumes prior distributions for mixing weights and the number of components. This model is called a mixture of…

Methodology · Statistics 2025-12-25 Fumiya Iwashige , Shintaro Hashimoto

Multivariate categorical data nested within households often include reported values that fail edit constraints---for example, a participating household reports a child's age as older than his biological parent's age---as well as missing…

Methodology · Statistics 2018-09-21 Olanrewaju Akande , Andrés Barrientos , Jerome P. Reiter

We introduce and discuss a kinetic framework describing the time evolution of the statistical distributions of a population divided into the compartments of susceptible, infectious, recovered, and resistant in the presence of a microbial…

Populations and Evolution · Quantitative Biology 2026-05-07 Marco Menale , Giuseppe Toscani , Mattia Zanella

Mammographic density is a dynamic risk factor for breast cancer and affects the sensitivity of mammography-based screening. While automated machine and deep learning-based methods provide more consistent and precise measurements compared to…

Zero inflation is a common nuisance while monitoring disease progression over time. This article proposes a new observation driven model for zero inflated and over-dispersed count time series. The counts given the past history of the…

Statistics Theory · Mathematics 2021-05-14 Vurukonda Sathish , Siuli Mukhopadhyay , Rashmi Tiwari

Given the rising complexity and burden of multimorbidity, it is crucial to provide evidence-based support for managing multimorbidity-related clinical outcomes. This study introduces a dynamic network approach to investigate conditional and…

Methodology · Statistics 2025-04-10 Hao Mei , Haonan Xiao , Ben-Chang Shia , Guanzhong Qiao , Yang Li

Rooted in genetics, human complex diseases are largely influenced by environmental factors. Existing literature has shown the power of integrative gene-environment interaction analysis by considering the joint effect of environmental…

Methodology · Statistics 2022-08-26 Jingyi Zhang , Xu Liu , Honglang Wang , Yuehua Cui

Diet is a risk factor for many diseases. In nutritional epidemiology, studying reproducible dietary patterns is critical to reveal important associations with health. However, it is challenging: diverse cultural and ethnic backgrounds may…

Applications · Statistics 2025-02-10 Roberta De Vito , Alejandra Avalos-Pacheco

Dynamic prediction of time-to-event outcomes using longitudinal data is highly useful in clinical research and practice. A common strategy is the joint modeling of longitudinal and time-to-event data. The shared random effect model has been…

Methodology · Statistics 2025-05-27 Wenhao Li , Zhe Yin , Liang Li

Non-equilibrium thermodynamics has long been an area of substantial interest to ecologists because most fundamental biological processes, such as protein synthesis and respiration, are inherently energy-consuming. Microbial communities are…

Populations and Evolution · Quantitative Biology 2022-01-19 Jacob Cook , Samraat Pawar , Robert G. Endres

Researchers are often interested in predicting outcomes, conducting clustering analysis to detect distinct subgroups of their data, or computing causal treatment effects. Pathological data distributions that exhibit skewness and…

Methodology · Statistics 2020-08-24 Arman Oganisian , Nandita Mitra , Jason Roy

Our main purpose is to compare classical nonself-centered, two-signal theoretical models of the adaptive immune system with a novel, self-centered, one-signal model developed by our research group. Our model hypothesizes that the immune…

Molecular Networks · Quantitative Biology 2020-12-02 Tamás Szabados , Csaba Kerepesi , Tibor Bakács

There exist several endeavors proposing a new family of extended distributions using the beta-generating technique. This is a well-known mechanism in developing flexible distributions, by embedding the cumulative distribution function (cdf)…

Statistics Theory · Mathematics 2019-12-17 M. Arashi , A. Bekker , D. de Waal , S. Makgai