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Related papers: Toward Actionable Digital Twins for Radiation-Base…

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Digital twins are becoming increasingly relevant in the Industrial Internet of Things and Industry 4.0, enhancing the capabilities and quality of various applications. However, the concept of \dts lacks a unified definition and faces…

Software Engineering · Computer Science 2024-08-27 Alexander Barbie , Wilhelm Hasselbring

Digital twins for cardiac electrophysiology are an enabling technology for precision cardiology. Current forward models are advanced enough to simulate the cardiac electric activity under different pathophysiological conditions and…

Optimization and Control · Mathematics 2025-05-05 Thomas Grandits , Karli Gillette , Gernot Plank , Simone Pezzuto

The dynamic nature of human health and comfort calls for adaptive systems that respond to individual physiological needs in real time. This paper presents an AI-enhanced digital twin framework that integrates biometric signals, specifically…

Signal Processing · Electrical Eng. & Systems 2025-05-13 Yiping Meng , Yiming Sun

With the accelerating availability of multimodal surgical data and real-time computation, Surgical Digital Twins (SDTs) have emerged as virtual counterparts that mirror, predict, and inform decisions across pre-, intra-, and postoperative…

This work shows how adaptivity can enhance value realization of digital twins in civil engineering. We focus on adapting the state transition models within digital twins represented through probabilistic graphical models. The bi-directional…

Machine Learning · Computer Science 2026-05-12 Eugenio Varetti , Matteo Torzoni , Marco Tezzele , Andrea Manzoni

In this paper, a hyperparameter tuning based Bayesian optimization of digital twins is carried out to diagnose various faults in grid connected inverters. As fault detection and diagnosis require very high precision, we channelize our…

Systems and Control · Electrical Eng. & Systems 2022-12-08 Pavol Mulinka , Subham Sahoo , Charalampos Kalalas , Pedro H. J. Nardelli

Artificial Intelligence (AI) and Large Language Models (LLMs) hold significant promise in revolutionizing healthcare, especially in clinical applications. Simultaneously, Digital Twin technology, which models and simulates complex systems,…

Artificial Intelligence · Computer Science 2024-09-27 Himanshu Pandey , Akhil Amod , Shivang , Kshitij Jaggi , Ruchi Garg , Abheet Jain , Vinayak Tantia

Digital twins are sophisticated software systems for the representation, monitoring, and control of cyber-physical systems, including automotive, avionics, smart manufacturing, and many more. Existing definitions and reference models of…

Software Engineering · Computer Science 2025-07-08 Jerome Pfeiffer , Jingxi Zhang , Benoit Combemale , Judith Michael , Bernhard Rumpe , Manuel Wimmer , Andreas Wortmann

Digital twins enable real-time simulation and prediction in engineering systems. This paper presents a novel framework for predictive digital twins of a headlamp heatsink, integrating physics-based reduced-order models (ROMs) from…

Machine Learning · Computer Science 2025-05-13 Tamilselvan Subramani , Sebastian Bartscher

Digital Twin (DT) technology has emerged as a transformative approach in healthcare, but its application in personalized patient care remains limited. This paper aims to present a practical implementation of DT in the management of chronic…

Quantitative Methods · Quantitative Biology 2025-07-17 Javad M Alizadeh , Mukesh K Patel , Huanmei Wu

Accurate prediction of tumor trajectories under standard-of-care (SoC) therapies remains a major unmet need in oncology. This capability is essential for optimizing treatment planning and anticipating disease progression. Conventional…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Moinak Bhattacharya , Gagandeep Singh , Prateek Prasanna

Network Digital Twins (NDTs) enable safe what-if analysis for 6G cloud-edge infrastructures, but adoption is often limited by fragmented workflows from telemetry to validation. We present a data-driven NDT framework that extends 6G-TWIN…

Digital twins (DTs) are an emerging capability in additive manufacturing (AM), set to revolutionize design optimization, inspection, in situ monitoring, and root cause analysis. AM DTs typically incorporate multimodal data streams, ranging…

Human-Computer Interaction · Computer Science 2024-05-22 Vuthea Chheang , Saurabh Narain , Garrett Hooten , Robert Cerda , Brian Au , Brian Weston , Brian Giera , Peer-Timo Bremer , Haichao Miao

The collaboration between humans and robots re-quires a paradigm shift not only in robot perception, reasoning, and action, but also in the design of the robotic cell. This paper proposes an optimization framework for designing…

Robotics · Computer Science 2024-10-21 Christian Cella , Marco Faroni , Andrea Zanchettin , Paolo Rocco

We evaluate calibration-based digital twins for IBM Quantum hardware, aiming to reproduce hardware measurement outcomes on classical simulators. We present a workflow that builds twins from downloadable calibration CSV files by mapping…

Quantum Physics · Physics 2026-03-17 Edgars Bautra , Maksims Dimitrijevs , Abuzer Yakaryilmaz

Digital twin technology has a huge potential for widespread applications in different industrial sectors such as infrastructure, aerospace, and automotive. However, practical adoptions of this technology have been slower, mainly due to a…

Machine Learning · Statistics 2020-06-16 Souvik Chakraborty , Sondipon Adhikari

Accurately modeling the spatiotemporal evolution of tumor morphology from baseline imaging is a pre-requisite for developing digital twin frameworks that can simulate disease progression and treatment response. Most existing approaches…

Image and Video Processing · Electrical Eng. & Systems 2025-10-01 Moinak Bhattacharya , Gagandeep Singh , Prateek Prasanna

In this paper, we study a digital twin (DT)-empowered integrated sensing, communication, and computation network. Specifically, the users perform radar sensing and computation offloading on the same spectrum, while unmanned aerial vehicles…

Signal Processing · Electrical Eng. & Systems 2023-10-27 Bin Li , Wenshuai Liu , Wancheng Xie , Ning Zhang , Yan Zhang

Digital twins (DTs), virtual simulated replicas of physical scenes, are transforming various industries. However, their potential in radio frequency (RF) sensing applications has been limited by the unidirectional nature of conventional RF…

Signal Processing · Electrical Eng. & Systems 2025-08-21 Xingyu Chen , Jianrong Ding , Kai Zheng , Xinmin Fang , Xinyu Zhang , Chris Xiaoxuan Lu , Zhengxiong Li

Physiologically based pharmacokinetic (PBPK) models provide a mechanistic framework for simulating radiopharmaceutical kinetics and estimating patient-specific absorbed doses (ADs). PBPK models incorporate prior knowledge of patient…

Medical Physics · Physics 2025-10-29 Nouran R. R. Zaid , Deni Hardiansyah , Tahir Yusufaly , Arman Rahmim