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AI scientists powered by large language models have demonstrated substantial promise in autonomously conducting experiments and facilitating scientific discoveries across various disciplines. While their capabilities are promising, these…

AI agents -- systems that combine foundation models with reasoning, planning, memory, and tool use -- are rapidly becoming a practical interface between natural-language intent and real-world computation. This survey synthesizes the…

Artificial Intelligence · Computer Science 2026-01-06 Bin Xu

AI agents are beginning to interact with each other directly and across internet platforms and physical environments, creating security challenges beyond traditional cybersecurity and AI safety frameworks. Free-form protocols are essential…

LLM-based reasoning models have enabled the development of agentic systems that act as co-scientists, assisting in multi-step scientific analysis. However, evaluating these systems is challenging, as it requires realistic, end-to-end…

Machine Learning · Computer Science 2026-02-24 Siba Smarak Panigrahi , Jovana Videnović , Maria Brbić

Scientific discovery is a complex cognitive process that has driven human knowledge and technological progress for centuries. While artificial intelligence (AI) has made significant advances in automating aspects of scientific reasoning,…

Machine Learning · Computer Science 2024-12-24 Chandan K Reddy , Parshin Shojaee

Remarkable advancements in modern generative foundation models have enabled the development of sophisticated and highly capable autonomous agents that can observe their environment, invoke tools, and communicate with other agents to solve…

Human-Computer Interaction · Computer Science 2024-12-17 Gagan Bansal , Jennifer Wortman Vaughan , Saleema Amershi , Eric Horvitz , Adam Fourney , Hussein Mozannar , Victor Dibia , Daniel S. Weld

Agentic AI systems -- Large Language Models (LLMs) augmented with planning, tool use, memory, and long-horizon interactions -- can execute complex tasks autonomously, but their multi-step trajectories introduce new failure modes that…

Artificial Intelligence · Computer Science 2026-05-26 Jinhu Qi , Muzhi Li , Jiahong Liu , Yuqin Shu , Dianzhi Yu , Shicheng Ma , Wenqian Cui , Yiyang Zhao , Yiyi Chen , Ruoxi Jiang , Irwin King , Zenglin Xu

Multi-agent systems (MAS) may encounter uncertainties in the form of unexpected environmental conditions, sub-optimal system configurations, and unplanned interactions between autonomous agents. The number of combinations of such…

Software Engineering · Computer Science 2022-05-12 Abigail C. Diller , Erik M. Fredericks

One of the major challenges we face with ethical AI today is developing computational systems whose reasoning and behaviour are provably aligned with human values. Human values, however, are notorious for being ambiguous, contradictory and…

Artificial Intelligence · Computer Science 2023-05-05 Nardine Osman , Mark d'Inverno

With the maturing of AI and multiagent systems research, we have a tremendous opportunity to direct these advances towards addressing complex societal problems. In pursuit of this goal of AI for Social Impact, we as AI researchers must go…

Computers and Society · Computer Science 2022-06-14 Andrew Perrault , Fei Fang , Arunesh Sinha , Milind Tambe

We envision "AI scientists" as systems capable of skeptical learning and reasoning that empower biomedical research through collaborative agents that integrate AI models and biomedical tools with experimental platforms. Rather than taking…

Modern information access ecosystems consist of mixtures of systems, such as retrieval systems and large language models, and increasingly rely on marketplaces to mediate access to models, tools, and data, making competition between systems…

Information Retrieval · Computer Science 2026-04-17 To Eun Kim , Alireza Salemi , Hamed Zamani , Fernando Diaz

The rise of agentic AI systems, where agents collaborate to perform diverse tasks, poses new challenges with observing, analyzing and optimizing their behavior. Traditional evaluation and benchmarking approaches struggle to handle the…

Artificial Intelligence · Computer Science 2025-03-11 Dany Moshkovich , Hadar Mulian , Sergey Zeltyn , Natti Eder , Inna Skarbovsky , Roy Abitbol

Autonomous materials research systems allow scientists to fail smarter, learn faster, and spend less resources in their studies. As these systems grow in number, capability, and complexity, a new challenge arises - how will they work…

Multiagent Systems · Computer Science 2023-03-21 A. Gilad Kusne , Austin McDannald

Autonomous multi-agent AI systems are poised to transform various industries, particularly software development and knowledge work. Understanding current perceptions among professionals is crucial for anticipating adoption challenges,…

Computers and Society · Computer Science 2025-06-04 Nikola Balic

Transformer-based large language models are rapidly advancing in the field of machine learning research, with applications spanning natural language, biology, chemistry, and computer programming. Extreme scaling and reinforcement learning…

Chemical Physics · Physics 2023-04-12 Daniil A. Boiko , Robert MacKnight , Gabe Gomes

A growing body of work pursues AI scientists capable of end-to-end autonomous scientific discovery. This position paper argues that although they already function as co-scientists, agentic AI scientists are not built for autonomous…

Artificial Intelligence · Computer Science 2026-05-12 Harshit Bisht , Vinay Kumar , Kevin Maik Jablonka , Mausam , N. M. Anoop Krishnan

As AI agents built on large language models (LLMs) become increasingly embedded in society, issues of coordination, control, delegation, and accountability are entangled with concerns over their reliability. To design and implement LLM…

Computers and Society · Computer Science 2025-12-09 R. Patrick Xian , Garry A. Gabison , Ahmed Alaa , Christoph Riedl , Grigorios G. Chrysos