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By means of atomistic molecular dynamics simulations we investigate the behaviour of poly(N-isopropylacrylamide), PNIPAM, in water at temperatures below and above the lower critical solution temperature (LCST), including the undercooled…

Soft Condensed Matter · Physics 2019-02-11 L. Tavagnacco , E. Zaccarelli , E. Chiessi

Poly(N-isopropylacrylamide), PNIPAM, is a widely studied polymer, which serves as a key constituent of nanostructured soft materials with responsive properties. Upon increasing temperature the PNIPAM polymer chain undergoes a reversible…

Soft Condensed Matter · Physics 2019-10-22 Letizia Tavagnacco , Emanuela Zaccarelli , Ester Chiessi

Poly-N-isopropylacrylamide (PNIPAM) phase diagram is explored in a wide range of temperature and pressure using extensive all-atom molecular dynamics simulations. By exploiting a simple model of an atactic linear polymer chain, we provide…

Soft Condensed Matter · Physics 2021-07-23 Letizia Tavagnacco , Ester Chiessi , Emanuela Zaccarelli

The experimentally observed swelling and collapse response of weakly charged polymers to the addition of specific salts displays quite convoluted behavior that is not easy to categorize. Here we use a minimalistic implicit solvent /…

Chemical Physics · Physics 2018-08-13 Richard Chudoba , Jan Heyda , Joachim Dzubiella

Poly(N-isopropylacrylamide) (PNIPAM) is a synthetic polymer that is widely studied for its thermoresponsive character. However, recent works also reported evidence of a low temperature (protein-like) dynamical transition around 225 K in…

We present an off-lattice statistical model of a single polymer chain in mixed solvent media. Taking into account a polymer conformational entropy, renormalization of solvent composition near the polymer backbone, the universal…

Soft Condensed Matter · Physics 2016-06-09 Yu. A. Budkov , A. L. Kolesnikov , N. N. Kalikin , M. G. Kiselev

Correlated anion and cation motion can significantly reduce the overall ion conductivity in electrolytes versus the ideal conductivity calculated based on the diffusion constants alone. Using coarse-grained molecular dynamics simulations,…

Soft Condensed Matter · Physics 2020-06-01 Kuan-Hsuan Shen , Lisa M. Hall

Effect of small additive molecules on the structural relaxation of polymer melts is investigated via molecular dynamics simulations. At a constant external pressure and a fixed number concentration of added molecules, the variation of…

Soft Condensed Matter · Physics 2019-07-30 Elias M. Zirdehi , Fathollah Varnik

We investigate the co-nonsolvency of poly-N-isopropyl acrylamide (PNiPAM) in different water-alcohol mixtures and show that this phenomenon is due to two distinct solvation contributions governing the phase behavior of PNiPAM in the…

Soft Condensed Matter · Physics 2014-10-29 Irmgard Bischofberger , Davide C. E. Calzolari , Veronique Trappe

Thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) particles of a nearly constant swelling ratio and with polydispersity indices (PDIs) varying over a wide range (7.4% - 48.9%) are synthesized to study the effects of polydispersity on…

Soft Condensed Matter · Physics 2017-11-01 Sanjay Kumar Behera , Debasish Saha , Paramesh Gadige , Ranjini Bandyopadhyay

We explore theoretically the modifications to the interactions between charged surfaces across an ionic solution caused by the presence of dielectric polymers. Although the chains are neutral, the polymer physics and the electrostatics are…

Soft Condensed Matter · Physics 2007-05-23 O. A. Croze , M. E. Cates

Polymer electrolytes typically exhibit diminished ionic conductivity due to the presence of correlation effects between the cations and anions. Microscopically, transient ionic aggregates, e.g. {\it ion-pairs}, {\it ion-triplets} or higher…

Materials Science · Physics 2008-04-15 Arijit Maitra , Andreas Heuer

Poly-N-isopropylacrylamide (PNIPAM) is a thermoresponsive polymer, an essential building block of a large family of soft smart materials. In neat water it undergoes upon heating at $\approx$305K a phase transition from swollen to collapsed…

Chemical Physics · Physics 2018-06-15 Vladimir Palivec , Denis Zadrazil , Jan Heyda

Thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) particles of different sizes are synthesized by varying the concentration of sodium dodecyl sulphate (SDS) in a one-pot method. The sizes, size polydispersities and the…

Soft Condensed Matter · Physics 2020-09-23 Chandeshwar Misra , Sanjay Kumar Behera , Ranjini Bandyopadhyay

Thermoresponsive polymer architectures have become integral building blocks of 'smart' functional materials in modern applications. For a large range of developments, e.g., for drug delivery or nanocatalytic carrier systems, the selective…

Soft Condensed Matter · Physics 2017-04-05 Matej Kanduc , Richard Chudoba , Karol Palczynski , Won Kyu Kim , Rafael Roa , Joachim Dzubiella

The encapsulation of fragile biomacromolecules is crucial for many biotechnological applications but remains challenging. Interfacial complexation (IC) in water-in-oil emulsions turned out to be an efficient process for the formation of…

Soft Condensed Matter · Physics 2021-09-30 L. Sixdenier , C. Tribet , E. Marie

Water mediates electrostatic interactions via the orientation of its dipoles around ions, molecules, and interfaces. This induced water polarization consequently influences multiple phenomena. In particular, water polarization modulated by…

It is well known that poly(N-isopropylacrylamide) (PNIPAm) exhibits an interesting, yet puzzling, phenomenon of co-non-solvency. Co-non-solvency occurs when two competing good solvents for PNIPAm, such as water and alcohol, are mixed…

Soft Condensed Matter · Physics 2016-01-19 Tiago E. de Oliveira , Paulo A. Netz , Debashish Mukherji , Kurt Kremer

Colloidal microgel particles such as poly(N-isopropylacrylamide) (PNIPAM) shrink reversibly in an aqueous medium due to the expulsion of water at a volume phase transition temperature, VPTT $\sim$33$^\circ$C. Romeo et al. [Adv. Mater. 2010,…

Soft Condensed Matter · Physics 2025-11-06 Sayantan Chanda , Chandeshwar Misra , Ranjini Bandyopadhyay

The long debated protein dynamical transition was recently found also in non-biological macromolecules, such as poly-N-isopropylacrylamide (PNIPAM) microgels. Here, by using atomistic molecular dynamics simulations, we report a description…

Soft Condensed Matter · Physics 2019-03-14 Letizia Tavagnacco , Ester Chiessi , Marco Zanatta , Andrea Orecchini , Emanuela Zaccarelli
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