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Large Language Models (LLMs) and multi-agent systems have shown impressive capabilities in natural language tasks but face challenges in clinical trial applications, primarily due to limited access to external knowledge. Recognizing the…

Computation and Language · Computer Science 2024-07-23 Ling Yue , Sixue Xing , Jintai Chen , Tianfan Fu

Skin cancer is one of the most common types of malignancy, affecting a large population and causing a heavy economic burden worldwide. Over the last few years, computer-aided diagnosis has been rapidly developed and make great progress in…

Computer Vision and Pattern Recognition · Computer Science 2022-03-31 Yongwei Wang , Yuheng Wang , Tim K. Lee , Chunyan Miao , Z. Jane Wang

A lot of deep learning (DL) research these days is mainly focused on improving quantitative metrics regardless of other factors. In human-centered applications, like skin lesion classification in dermatology, DL-driven clinical decision…

Image and Video Processing · Electrical Eng. & Systems 2023-09-01 Theodor Cheslerean-Boghiu , Melia-Evelina Fleischmann , Theresa Willem , Tobias Lasser

The deployment of vision-language models (VLMs) in dermatology is hindered by the trilemma of high computational costs, extreme data scarcity, and the black-box nature of deep learning. To address these challenges, we present SkinCLIP-VL, a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Zhixiang Lu , Shijie Xu , Kaicheng Yan , Xuyue Cai , Chong Zhang , Yulong Li , Angelos Stefanidis , Anh Nguyen , Jionglong Su

The rise of Artificial Intelligence creates great promise in the field of medical discovery, diagnostics and patient management. However, the vast complexity of all medical domains require a more complex approach that combines machine…

Computation and Language · Computer Science 2025-03-28 Dimitrios P. Panagoulias , Evridiki Tsoureli-Nikita , Maria Virvou , George A. Tsihrintzis

Differential Diagnosis (DDx) is a fundamental yet complex aspect of clinical decision-making, in which physicians iteratively refine a ranked list of possible diseases based on symptoms, antecedents, and medical knowledge. While recent…

Computation and Language · Computer Science 2025-06-16 Daniel Rose , Chia-Chien Hung , Marco Lepri , Israa Alqassem , Kiril Gashteovski , Carolin Lawrence

Comprehending genomic information is essential for biomedical research, yet extracting data from complex distributed databases remains challenging. Large language models (LLMs) offer potential for genomic Question Answering (QA) but face…

Artificial Intelligence · Computer Science 2026-01-16 Kimia Abedini , Farzad Shami , Gianmaria Silvello

Skin diseases are among the most prevalent health issues, and accurate computer-aided diagnosis methods are of importance for both dermatologists and patients. However, most of the existing methods overlook the essential domain knowledge…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Yan-Jie Zhou , Wei Liu , Yuan Gao , Jing Xu , Le Lu , Yuping Duan , Hao Cheng , Na Jin , Xiaoyong Man , Shuang Zhao , Yu Wang

Large Language Models (LLMs) have made significant progress in various fields. However, challenges remain in Multi-Disciplinary Team (MDT) medical consultations. Current research enhances reasoning through role assignment, task…

Artificial Intelligence · Computer Science 2025-03-19 Kai Chen , Xinfeng Li , Tianpei Yang , Hewei Wang , Wei Dong , Yang Gao

The integration of deep learning-based glaucoma detection with large language models (LLMs) presents an automated strategy to mitigate ophthalmologist shortages and improve clinical reporting efficiency. However, applying general LLMs to…

Multiagent Systems · Computer Science 2025-12-18 Philip R. Liu , Sparsh Bansal , Jimmy Dinh , Aditya Pawar , Ramani Satishkumar , Shail Desai , Neeraj Gupta , Xin Wang , Shu Hu

Large Language Models (LLMs), prominently highlighted by the recent evolution in the Generative Pre-trained Transformers (GPT) series, have displayed significant prowess across various domains, such as aiding in healthcare diagnostics and…

Portfolio Management · Quantitative Finance 2023-09-08 Yang Li , Yangyang Yu , Haohang Li , Zhi Chen , Khaldoun Khashanah

Vision-Language Models (VLMs) show promise in medical image analysis, yet their capacity for structured reasoning in complex domains like dermatology is often limited by data scarcity and the high computational cost of advanced training…

Computation and Language · Computer Science 2025-10-03 Ismam Nur Swapnil , Aranya Saha , Tanvir Ahmed Khan , Mohammad Ariful Haque

Diagnosing and treating skin diseases require advanced visual skills across domains and the ability to synthesize information from multiple imaging modalities. While current deep learning models excel at specific tasks like skin cancer…

Paucity of medical data severely limits the generalizability of diagnostic ML models, as the full spectrum of disease variability can not be represented by a small clinical dataset. To address this, diffusion models (DMs) have been…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Janet Wang , Yunbei Zhang , Zhengming Ding , Jihun Hamm

Recent advancements in artificial intelligence (AI) have precipitated significant breakthroughs in healthcare, particularly in refining diagnostic procedures. However, previous studies have often been constrained to limited functionalities.…

Artificial Intelligence · Computer Science 2024-07-08 Asma Alkhaldi , Raneem Alnajim , Layan Alabdullatef , Rawan Alyahya , Jun Chen , Deyao Zhu , Ahmed Alsinan , Mohamed Elhoseiny

Multimodal large language models (LLMs) are increasingly used to generate dermatology diagnostic narratives directly from images. However, reliable evaluation remains the primary bottleneck for responsible clinical deployment. We introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Yuhao Shen , Jiahe Qian , Shuping Zhang , Zhangtianyi Chen , Tao Lu , Juexiao Zhou

General-purpose Large Vision-Language Models (LVLMs), despite their massive scale, often falter in dermatology due to "diffuse attention" - the inability to disentangle subtle pathological lesions from background noise. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Lijun Liu , Linwei Chen , Zhishou Zhang , Meng Tian , Hengfu Cui , Ruiyang Li , Zhaocheng Liu , Qiang Ju , Qianxi Li , Hong-Yu Zhou

Deep convolutional neural network (DCNN) models have been widely explored for skin disease diagnosis and some of them have achieved the diagnostic outcomes comparable or even superior to those of dermatologists. However, broad…

Computer Vision and Pattern Recognition · Computer Science 2022-02-14 Peng Yao , Shuwei Shen , Mengjuan Xu , Peng Liu , Fan Zhang , Jinyu Xing , Pengfei Shao , Benjamin Kaffenberger , Ronald X. Xu

Skin cancer is one of the most prevalent and deadly forms of cancer worldwide, highlighting the critical importance of early detection and diagnosis in improving patient outcomes. Deep learning (DL) has shown significant promise in…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Runhao Liu , Ziming Chen , Guangzhen Yao , Peng Zhang

Skin diseases, such as skin cancer, are a significant public health issue, and early diagnosis is crucial for effective treatment. Artificial intelligence (AI) algorithms have the potential to assist in triaging benign vs malignant skin…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Nusrat Munia , Abdullah-Al-Zubaer Imran