Related papers: Passivity-Based Control of Electrographic Seizures…
Closed-loop brain stimulation holds potential as personalized treatment for drug-resistant epilepsy (DRE) but still suffers from limitations that result in highly variable efficacy. First, stimulation is typically delivered upon detection…
Recent advances in control theory yield closed-loop neurostimulations for suppressing epileptiform seizures. These advances are illustrated by computer experiments which are easy to implement and to tune. The feedback synthesis is provided…
Over one third of the estimated 3 million people with epilepsy in the US are medication resistant. Responsive neurostimulation from chronically implanted electrodes provides a promising treatment option and alternative to resective surgery.…
Electrical neuromodulation as a palliative treatment has been increasingly used in the control of epilepsy. However, current neuromodulations commonly implement predetermined actuation strategies and lack the capability of self-adaptively…
Epilepsy is a dynamic and complex neurological disease affecting about 1% of the worldwide population, among which 30% of the patients are drug-resistant. Epilepsy is characterized by recurrent episodes of paroxysmal neural discharges (the…
Information transmission in the human brain is a fundamentally dynamic network process. In partial epilepsy, this process is perturbed and highly synchronous seizures originate in a local network, the so-called epileptogenic zone (EZ),…
Medically uncontrolled epileptic seizures affect nearly 15 million people worldwide, resulting in enormous economic and psychological burdens. Treatment of medically refractory epilepsy is essential for patients to achieve remission,…
Introduction: Approximately 23 million or 30% of epilepsy patients worldwide suffer from drug-resistant epilepsy (DRE). The unpredictability of seizure occurrences, which causes safety issues as well as social concerns, restrict the…
This paper introduces an innovative framework designed for progressive (granular in time to onset) prediction of seizures through the utilization of a Deep Learning (DL) methodology based on non-invasive multi-modal sensor networks.…
The electrical stimulation to the seizure onset zone (SOZ) serves as an efficient approach to seizure suppression. Recently, seizure dynamics have gained widespread attendance in its network propagation mechanisms. Compared with the direct…
Epilepsy is a neurological disease characterized by recurrent and spontaneous seizures. It affects approximately 50 million people worldwide. In majority of the cases accurate diagnosis of the disease can be made without using any…
Epilepsy is a common neurological disorder characterized by abrupt seizures. Although seizures may appear random, they are often preceded by early warning signs in neural signals, notably, critical slowing down, a phenomenon in which the…
Epilepsy which is characterized by seizures is studied using EEG signals by recording the electrical activity of the brain. Different types of communication between different parts of the brain are characterized by many state of the art…
Epilepsy represents the most prevalent neurological disease in the world. One-third of people suffering from mesial temporal lobe epilepsy (MTLE) exhibit drug resistance, urging the need to develop new treatments. A key part in anti-seizure…
Epileptic seizures arise from abnormally synchronised neural activity and remain a major global health challenge, affecting more than 50 million people worldwide. Despite advances in pharmacological interventions, a significant proportion…
Epilepsy, affecting approximately 50 million people globally, is characterized by abnormal brain activity and remains challenging to treat. The diagnosis of epilepsy relies heavily on electroencephalogram (EEG) data, where specialists…
Objective: Epilepsy is one of the most prevalent neurological diseases among humans and can lead to severe brain injuries, strokes, and brain tumors. Early detection of seizures can help to mitigate injuries, and can be used to aid the…
In this paper, we introduce SeizNet, a closed-loop system for predicting epileptic seizures through the use of Deep Learning (DL) method and implantable sensor networks. While pharmacological treatment is effective for some epilepsy…
Identifying seizure activities in non-stationary electroencephalography (EEG) is a challenging task, since it is time-consuming, burdensome, and dependent on expensive human resources and subject to error and bias. A computerized seizure…
Patients with epilepsy can manifest short, sub-clinical epileptic "bursts" in addition to full-blown clinical seizures. We believe the relationship between these two classes of events---something not previously studied…