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Dynamic programming (DP) based algorithms are essential yet compute-intensive parts of numerous bioinformatics pipelines, which typically involve populating a 2-D scoring matrix based on a recursive formula, optionally followed by a…

Hardware Architecture · Computer Science 2024-11-07 Yingqi Cao , Anshu Gupta , Jason Liang , Yatish Turakhia

GPU kernel optimization has long been a central challenge at the intersection of high-performance computing and machine learning. Efficient kernels are crucial for accelerating large language model (LLM) training and serving, yet attaining…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-04 Anjiang Wei , Tianran Sun , Yogesh Seenichamy , Hang Song , Anne Ouyang , Azalia Mirhoseini , Ke Wang , Alex Aiken

Automatic code optimization remains a difficult challenge, particularly for complex loop nests on modern hardware. This paper investigates a novel approach to code optimization where Large Language Models (LLMs) guide the process through a…

Programming Languages · Computer Science 2025-12-30 Massinissa Merouani , Islem Kara Bernou , Riyadh Baghdadi

Developing efficient CUDA kernels is increasingly critical for AI applications such as large-scale LLM training. However, manual kernel design is both costly and time-consuming, motivating automatic approaches that leverage LLMs for code…

Machine Learning · Computer Science 2025-11-06 Zijian Zhang , Rong Wang , Shiyang Li , Yuebo Luo , Mingyi Hong , Caiwen Ding

With the decline of Moore's law, optimizing program performance has become a major focus of software research. However, high-level optimizations such as API and algorithm changes remain elusive due to the difficulty of understanding the…

Machine learning has been widely used to optimize complex engineering workflows across numerous domains. In integrated circuit design, modern flows (e.g., register-transfer level to physical layout) involve extensive configuration via…

Artificial Intelligence · Computer Science 2026-05-01 Amur Ghose , Andrew B. Kahng , Sayak Kundu , Zhiang Wang

Large language models (LLMs) are adopted for software and hardware design, yet these domains are still evaluated separately. Software benchmarks typically assume fixed hardware targets, while hardware benchmarks focus on component-level…

Hardware Architecture · Computer Science 2026-05-20 Pei-Huan Tsai , Kuan-Lin Chiu , William Baisi , Pin-Yu Chen , Luca P. Carloni

Refactoring is a constant activity in software development and maintenance. Scale and maintain software systems are based on code refactoring. However, this process is still labor intensive, as it requires programmers to analyze the…

GPU kernel optimization is fundamental to modern deep learning but remains a highly specialized task requiring deep hardware expertise. Despite strong performance in general programming, large language models (LLMs) remain uncompetitive…

Multi-agent frameworks with Large Language Models (LLMs) have become promising tools for generating general-purpose programming languages using test-driven development, allowing developers to create more accurate and robust code. However,…

Quantum Physics · Physics 2025-07-04 Charlie Campbell , Hao Mark Chen , Wayne Luk , Hongxiang Fan

The increasing complexity and demand for faster, energy-efficient hardware designs necessitate innovative High-Level Synthesis (HLS) methodologies. This paper explores the potential of Large Language Models (LLMs) to streamline or replace…

Hardware Architecture · Computer Science 2024-08-21 Yuchao Liao , Tosiron Adegbija , Roman Lysecky

Due to decelerating gains in single-core CPU performance, computationally expensive simulations are increasingly executed on highly parallel hardware platforms. Agent-based simulations, where simulated entities act with a certain degree of…

Multiagent Systems · Computer Science 2018-07-04 Jiajian Xiao , Philipp Andelfinger , David Eckhoff , Wentong Cai , Alois Knoll

In this study, we propose VibeCodeHPC, a multi-agent system based on large language models (LLMs) for the automatic tuning of high-performance computing (HPC) programs on supercomputers. VibeCodeHPC adopts Claude Code as its backend and…

Software Engineering · Computer Science 2026-02-13 Shun-ichiro Hayashi , Koki Morita , Daichi Mukunoki , Tetsuya Hoshino , Takahiro Katagiri

Recently, researchers have proposed many multi-agent frameworks for function-level code generation, which aim to improve software development productivity by automatically generating function-level source code based on task descriptions. A…

Software Engineering · Computer Science 2025-04-08 Yueheng Zhu , Chao Liu , Xuan He , Xiaoxue Ren , Zhongxin Liu , Ruwei Pan , Hongyu Zhang

High-Level Synthesis (HLS) plays a crucial role in modern hardware design by transforming high-level code into optimized hardware implementations. However, progress in applying machine learning (ML) to HLS optimization has been hindered by…

Hardware Architecture · Computer Science 2025-08-05 Zedong Peng , Zeju Li , Mingzhe Gao , Qiang Xu , Chen Zhang , Jieru Zhao

In industrial control systems, the generation and verification of Programmable Logic Controller (PLC) code are critical for ensuring operational efficiency and safety. While Large Language Models (LLMs) have made strides in automated code…

Software Engineering · Computer Science 2024-12-30 Zihan Liu , Ruinan Zeng , Dongxia Wang , Gengyun Peng , Jingyi Wang , Qiang Liu , Peiyu Liu , Wenhai Wang

Recent large language models (LLMs) have demonstrated strong capabilities in understanding and generating code, from competitive programming to repository-level software engineering. In emerging agentic systems, code is no longer only a…

Large language models and AI agents have recently shown promise in automating software performance optimization, but existing approaches predominantly rely on local, syntax-driven code transformations. This limits their ability to reason…

Software Engineering · Computer Science 2026-03-17 Huiyun Peng , Parth Vinod Patil , Antonio Zhong Qiu , George K. Thiruvathukal , James C. Davis

Accelerating applications through the design of hardware accelerators can significantly enhance system performance and energy efficiency. Despite advances, such as high-level synthesis (HLS), designing accelerators for complex applications…

Hardware Architecture · Computer Science 2026-05-18 Abinand Nallathambi , Christopher Knight , Shantanu Ganguly , Wilfried Haensch , Anand Raghunathan

Hardware synthesis is a general term used to refer to the processes involved in automatically generating a hardware design from its specification. High-level synthesis (HLS) could be defined as the translation from a behavioral description…

Other Computer Science · Computer Science 2019-05-07 Issam Damaj