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Neural computation in biological and artificial networks relies on the nonlinear summation of many inputs. The structural connectivity matrix of synaptic weights between neurons is a critical determinant of overall network function, but…

Neurons and Cognition · Quantitative Biology 2022-07-01 Tirthabir Biswas , James E. Fitzgerald

We introduce a neural architecture for navigation in novel environments. Our proposed architecture learns to map from first-person views and plans a sequence of actions towards goals in the environment. The Cognitive Mapper and Planner…

Computer Vision and Pattern Recognition · Computer Science 2019-02-08 Saurabh Gupta , Varun Tolani , James Davidson , Sergey Levine , Rahul Sukthankar , Jitendra Malik

Inspired by biology's most sophisticated computer, the brain, neural networks constitute a profound reformulation of computational principles. Remarkably, analogous high-dimensional, highly-interconnected computational architectures also…

Disordered Systems and Neural Networks · Physics 2024-01-23 Constantine Glen Evans , Jackson O'Brien , Erik Winfree , Arvind Murugan

A cognitive map is an internal model which encodes the abstract relationships among entities in the world, giving humans and animals the flexibility to adapt to new situations, with a strong out-of-distribution (OOD) generalization that…

Machine Learning · Computer Science 2026-05-12 Victor Rambaud , Salvador Mascarenhas , Yair Lakretz

Image compression and reconstruction are crucial for various digital applications. While contemporary neural compression methods achieve impressive compression rates, the adoption of such technology has been largely hindered by the…

Machine Learning · Computer Science 2025-10-06 Ethan G. Rogers , Cheng Wang

An approach that combines Self-Organizing maps, hierarchical clustering and network components is presented, aimed at comparing protein conformational ensembles obtained from multiple Molecular Dynamic simulations. As a first result the…

Computational Engineering, Finance, and Science · Computer Science 2013-10-01 Domenico Fraccalvieri , Laura Bonati , Fabio Stella

A fundamental cognitive process is the ability to map value and identity onto objects as we learn about them. Exactly how such mental constructs emerge and what kind of space best embeds this mapping remains incompletely understood. Here we…

Neurons and Cognition · Quantitative Biology 2019-05-31 Evelyn Tang , Marcelo G. Mattar , Chad Giusti , Sharon L. Thompson-Schill , Danielle S. Bassett

This paper investigates how the compositional structure of neural networks shapes their optimization landscape and training dynamics. We analyze the gradient flow associated with overparameterized optimization problems, which can be…

Machine Learning · Computer Science 2025-11-14 Arthur Castello Branco de Oliveira , Dhruv Jatkar , Eduardo Sontag

The neural manifold hypothesis postulates that the activity of a neural population forms a low-dimensional manifold whose structure reflects that of the encoded task variables. In this work, we combine topological deep generative models and…

Neurons and Cognition · Quantitative Biology 2023-04-26 Francisco Acosta , Sophia Sanborn , Khanh Dao Duc , Manu Madhav , Nina Miolane

Hyperparameters and learning algorithms for neuromorphic hardware are usually chosen by hand. In contrast, the hyperparameters and learning algorithms of networks of neurons in the brain, which they aim to emulate, have been optimized…

Neural and Evolutionary Computing · Computer Science 2019-06-11 Thomas Bohnstingl , Franz Scherr , Christian Pehle , Karlheinz Meier , Wolfgang Maass

Tabular datasets with low-sample-size or many variables are prevalent in biomedicine. Practitioners in this domain prefer linear or tree-based models over neural networks since the latter are harder to interpret and tend to overfit when…

Machine Learning · Computer Science 2022-02-09 Junchen Yang , Ofir Lindenbaum , Yuval Kluger

Mental and cognitive representations are believed to reside on low-dimensional, non-linear manifolds embedded within high-dimensional brain activity. Uncovering these manifolds is key to understanding individual differences in brain…

Machine Learning · Computer Science 2025-05-02 Eloy Geenjaar , Vince Calhoun

This work is concerned with a representation of shapes that disentangles fine, local and possibly repeating geometry, from global, coarse structures. Achieving such disentanglement leads to two unrelated advantages: i) a significant…

Computer Vision and Pattern Recognition · Computer Science 2022-04-06 Luca Morreale , Noam Aigerman , Paul Guerrero , Vladimir G. Kim , Niloy J. Mitra

Neuroscience models commonly have a high number of degrees of freedom and only specific regions within the parameter space are able to produce dynamics of interest. This makes the development of tools and strategies to efficiently find…

In recent years, the state-of-the-art in deep learning has been dominated by very large models that have been pre-trained on vast amounts of data. The paradigm is very simple: investing more computational resources (optimally) leads to…

Machine Learning · Computer Science 2024-05-24 Sotiris Anagnostidis , Gregor Bachmann , Imanol Schlag , Thomas Hofmann

There is a concerted effort to build domain-general artificial intelligence in the form of universal neural network models with sufficient computational flexibility to solve a wide variety of cognitive tasks but without requiring…

Neural and Evolutionary Computing · Computer Science 2023-03-27 Jascha Achterberg , Danyal Akarca , Moataz Assem , Moritz Heimbach , Duncan E. Astle , John Duncan

Surrogate models driven by sizeable datasets and scientific machine-learning methods have emerged as an attractive microstructure simulation tool with the potential to deliver predictive microstructure evolution dynamics with huge savings…

Materials Science · Physics 2024-01-22 Shaoxun Fan , Andrew L. Hitt , Ming Tang , Babak Sadigh , Fei Zhou

Understanding how receptive fields emerge and organize within brain networks and how neural dynamics couple with stimuli space is fundamental to neuroscience. Models often rely on fine-tuning connectivity to match empirical data, which may…

Neurons and Cognition · Quantitative Biology 2026-01-07 Vasilii Tiselko , Alexander Gorsky , Yuri Dabaghian

The biomolecules in and around a living cell -- proteins, nucleic acids, lipids, carbohydrates -- continuously sample myriad conformational states that are thermally accessible at physiological temperatures. Simultaneously, a given…

Biomolecules · Quantitative Biology 2014-07-15 Cameron Mura , Charles E. McAnany

We apply recent advances in machine learning and computer vision to a central problem in materials informatics: The statistical representation of microstructural images. We use activations in a pre-trained convolutional neural network to…

Computational Physics · Physics 2018-12-04 Nicholas Lubbers , Turab Lookman , Kipton Barros
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