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The morphological fingerprint in the brain is capable of identifying the uniqueness of an individual. However, whether such individual patterns are present in perinatal brains, and which morphological attributes or cortical regions better…

Machine Learning · Computer Science 2023-11-28 Boyang Wang , Weihao Zheng , Ying Wang , Zhe Zhang , Yuchen Sheng , Minmin Wang

This review paper explores recent advances in deep learning approaches for non-invasive cognitive impairment detection. We examine various non-invasive indicators of cognitive decline, including speech and language, facial, and motoric…

Machine Learning · Computer Science 2025-04-16 Muath Alsuhaibani , Ali Pourramezan Fard , Jian Sun , Farida Far Poor , Peter S. Pressman , Mohammad H. Mahoor

Early detection of autism, a neurodevelopmental disorder marked by social communication challenges, is crucial for timely intervention. Recent advancements have utilized naturalistic home videos captured via the mobile application…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Marie Huynh , Aaron Kline , Saimourya Surabhi , Kaitlyn Dunlap , Onur Cezmi Mutlu , Mohammadmahdi Honarmand , Parnian Azizian , Peter Washington , Dennis P. Wall

Digital phenotyping enables continuous passive monitoring of behavior and physiology, offering a promising paradigm for early detection of psychotic relapse. In this work, we develop and systematically study two smartwatch-based frameworks…

Machine Learning · Computer Science 2026-05-14 Nikolaos Tsalkitzis , Panagiotis P. Filntisis , Petros Maragos , Niki Efthymiou

Artificial Intelligence (AI) chatbots powered by a large language model (LLM) are entering young children's learning and play, yet little is known about how young children construe these agents or how such construals relate to engagement.…

Human-Computer Interaction · Computer Science 2025-12-04 Pilyoung Kim , Jenna H. Chin , Yun Xie , Nolan Brady , Tom Yeh , Sujin Yang

Infants' spontaneous and voluntary movements mirror developmental integrity of brain networks since they require coordinated activation of multiple sites in the central nervous system. Accordingly, early detection of infants with atypical…

Computer Vision and Pattern Recognition · Computer Science 2019-12-19 Manu Airaksinen , Okko Räsänen , Elina Ilén , Taru Häyrinen , Anna Kivi , Viviana Marchi , Anastasia Gallen , Sonja Blom , Anni Varhe , Nico Kaartinen , Leena Haataja , Sampsa Vanhatalo

Autism Spectrum Disorder (ASD) is a rapidly growing neurodevelopmental disorder. Performing a timely intervention is crucial for the growth of young children with ASD, but traditional clinical screening methods lack objectivity. This study…

Computer Vision and Pattern Recognition · Computer Science 2024-09-02 Xiang Li , Lizhou Fan , Hanbo Wu , Kunping Chen , Xiaoxiao Yu , Chao Che , Zhifeng Cai , Xiuhong Niu , Aihua Cao , Xin Ma

The human brains are organized into hierarchically modular networks facilitating efficient and stable information processing and supporting diverse cognitive processes during the course of development. While the remarkable reconfiguration…

Neurons and Cognition · Quantitative Biology 2020-09-16 Xuyun Wen , Liming Hsu , Weili Lin , Han Zhang , Dinggang Shen

Assessment of spontaneous movements can predict the long-term developmental disorders in high-risk infants. In order to develop algorithms for automated prediction of later disorders, highly precise localization of segments and joints by…

Computer Vision and Pattern Recognition · Computer Science 2022-02-21 Daniel Groos , Lars Adde , Ragnhild Støen , Heri Ramampiaro , Espen A. F. Ihlen

Dementia affects cognitive functions of adults, including memory, language, and behaviour. Standard diagnostic biomarkers such as MRI are costly, whilst neuropsychological tests suffer from sensitivity issues in detecting dementia onset.…

Computation and Language · Computer Science 2023-12-27 Dimitris Gkoumas , Bo Wang , Adam Tsakalidis , Maria Wolters , Arkaitz Zubiaga , Matthew Purver , Maria Liakata

Understanding the development of adolescent behavioral and mental health outcomes requires integrating genetic predisposition, environmental exposures, and neurobiological processes over time. Here, we present a unified quantitative…

Other Quantitative Biology · Quantitative Biology 2026-05-06 Mengman Wei , Qian Peng

Learning requires the traversal of inherently distinct cognitive states to produce behavioral adaptation. Yet, tools to explicitly measure these states with non-invasive imaging -- and to assess their dynamics during learning -- remain…

A major challenge in medical image analysis is the automated detection of biomarkers from neuroimaging data. Traditional approaches, often based on image registration, are limited in capturing the high variability of cortical organisation…

Computer Vision and Pattern Recognition · Computer Science 2022-11-17 Dániel Unyi , Bálint Gyires-Tóth

Cognitive decline is highly heterogeneous across individuals, which complicates prognosis, trial design, and treatment planning. We present the Personalized Cognitive Decline Assessment Digital Twin (PCD-DT), a multimodal and…

Artificial Intelligence · Computer Science 2026-05-01 Bulent Soykan , Gulsah Hancerliogullari Koksalmis , Hsin-Hsiung Huang , Laura J. Brattain

Exploring the developing brain is a major issue in understanding what enables children to acquire amazing abilities, and how early disruptions can lead to a wide range of neurodevelopmental disorders. MRI plays a key role here by providing…

Neurons and Cognition · Quantitative Biology 2024-01-01 Jessica Dubois

The Alberta Infant Motor Scale (AIMS) is a well-known assessment scheme that evaluates the gross motor development of infants by recording the number of specific poses achieved. With the aid of the image-based pose recognition model, the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-05 Cheng-Yen Yang , Zhongyu Jiang , Shih-Yu Gu , Jenq-Neng Hwang , Jang-Hee Yoo

Face recognition for infants and toddlers presents unique challenges due to rapid facial morphology changes, high inter-class similarity, and limited dataset availability. This study evaluates the performance of four deep learning-based…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Afzal Hossain , Mst Rumana Sumi , Stephanie Schuckers

Early diagnosis of dementia, particularly in the prodromal stage (i.e., mild cognitive impairment, or MCI), has become a research and clinical priority but remains challenging. Automated analysis of the drawing process has been studied as a…

Signal Processing · Electrical Eng. & Systems 2022-11-17 Yasunori Yamada , Masatomo Kobayashi , Kaoru Shinkawa , Miyuki Nemoto , Miho Ota , Kiyotaka Nemoto , Tetsuaki Arai

Children learn powerful internal models of the world around them from a few years of egocentric visual experience. Can such internal models be learned from a child's visual experience with highly generic learning algorithms or do they…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 A. Emin Orhan , Wentao Wang , Alex N. Wang , Mengye Ren , Brenden M. Lake

Studies have shown that children can be exposed to smart devices at a very early age. This has important implications on research in children-computer interaction, children online safety and early education. Many systems have been built…

Human-Computer Interaction · Computer Science 2018-08-07 Toan Nguyen , Aditi Roy , Nasir Memon