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Distribution regression has recently attracted much interest as a generic solution to the problem of supervised learning where labels are available at the group level, rather than at the individual level. Current approaches, however, do not…

Machine Learning · Statistics 2021-01-18 Ho Chung Leon Law , Danica J. Sutherland , Dino Sejdinovic , Seth Flaxman

Acute infectious diseases are transmitted over networks of social contacts. Epidemic models are used to predict the spread of emergent pathogens and compare intervention strategies. Many of these models assume equal probability of contact…

Applications · Statistics 2016-11-25 Gail E. Potter , Niel Hens

In stopping the spread of infectious diseases, pathogen genomic data can be used to reconstruct transmission events and characterize population-level sources of infection. Most approaches for identifying transmission pairs do not account…

The contact structure between hosts has a critical influence on disease spread. However, most networkbased models used in epidemiology tend to ignore heterogeneity in the weighting of contacts. This assumption is known to be at odds with…

Populations and Evolution · Quantitative Biology 2012-09-03 Christel Kamp , Mathieu Moslonka-Lefebvre , Samuel Alizon

In this paper, we are concerned with the stochastic susceptible-infectious-susceptible (SIS) epidemic model on the complete graph with $n$ vertices. This model has two parameters, which are the infection rate and the recovery rate. By…

Probability · Mathematics 2020-12-02 Huazheng Bu , Xiaofeng Xue

Network-based models of epidemic spread have become increasingly popular in recent decades. Despite a rich foundation of such models, few low-dimensional systems for modeling SIS-type diseases have been proposed that manage to capture the…

Dynamical Systems · Mathematics 2021-01-01 Carl Corcoran , Alan Hastings

Contact matrices are a commonly adopted data representation, used to develop compartmental models for epidemic spreading, accounting for the contact heterogeneities across age groups. Their estimation, however, is generally time and effort…

We study the Susceptible-Infected-Susceptible model of the spread of an endemic infection. We calculate an exact expression for the mean number of transmissions for all values of the population and the infectivity. We derive the large-N…

Populations and Evolution · Quantitative Biology 2007-09-20 David A. Kessler

In Part 1, we introduced a stochastic model of an infectious disease, based on the BDI (birth and death with immigration) process. We showed that random processes defined by this model can capture the essence of the stochastic, often…

Populations and Evolution · Quantitative Biology 2021-01-28 Hisashi Kobayashi

Stochastic epidemic models, generally more realistic than deterministic counterparts, have often been seen too complex for rigorous mathematical analysis because of level of details it requires to comprehensively capture the dynamics of…

Populations and Evolution · Quantitative Biology 2018-06-13 Xin Liu , Anuj Mubayi , Dominik Reinhold , Liu Zhu

In variational inference, the benefits of Bayesian models rely on accurately capturing the true posterior distribution. We propose using neural samplers that specify implicit distributions, which are well-suited for approximating complex…

Machine Learning · Computer Science 2023-11-10 Anshuk Uppal , Kristoffer Stensbo-Smidt , Wouter Boomsma , Jes Frellsen

Many epidemic models are naturally defined as individual-based models: where we track the state of each individual within a susceptible population. Inference for individual-based models is challenging due to the high-dimensional state-space…

Methodology · Statistics 2025-08-04 Lorenzo Rimella , Christopher Jewell , Paul Fearnhead

Among various spatio-temporal prediction tasks, epidemic forecasting plays a critical role in public health management. Recent studies have demonstrated the strong potential of spatio-temporal graph neural networks (STGNNs) in extracting…

Machine Learning · Computer Science 2025-12-30 Yufan Zheng , Wei Jiang , Tong Chen , Alexander Zhou , Nguyen Quoc Viet Hung , Choujun Zhan , Hongzhi Yin

Background: Mendelian randomization (MR) is a useful approach to causal inference from observational studies when randomised controlled trials are not feasible. However, study heterogeneity of two association studies required in MR is often…

Methodology · Statistics 2021-12-16 Linyi Zou , Hui Guo , Carlo Berzuini

Following the emergence of a novel coronavirus (SARS-CoV-2) and its spread outside of China, Europe has experienced large epidemics. In response, many European countries have implemented unprecedented non-pharmaceutical interventions…

This paper introduces a hierarchical framework to incorporate Hellinger distance methods into Bayesian analysis. We propose to modify a prior over non-parametric densities with the exponential of twice the Hellinger distance between a…

Methodology · Statistics 2013-09-27 Yuefeng Wu , Giles Hooker

In low and middle income countries, household surveys are a valuable source of information for a range of health and demographic indicators. Increasingly, subnational estimates are required for targeting interventions and evaluating…

Methodology · Statistics 2020-09-21 Katie Wilson , Jon Wakefield

To increase situational awareness and support evidence-based policy-making, we formulated two types of mathematical models for COVID-19 transmission within a regional population. One is a fitting function that can be calibrated to reproduce…

Individual contributions to the spread of an epidemic vary widely due to an individual's location in a social network and their intrinsic ability to spread or contract diseases. While the effect of heterogeneous population structure and…

Populations and Evolution · Quantitative Biology 2026-05-14 Abhay Gupta , Nicholas W. Landry

Human behavior plays a critical role in shaping epidemic trajectories. During health crises, people respond in diverse ways in terms of self-protection and adherence to recommended measures, largely reflecting differences in how individuals…

Physics and Society · Physics 2026-01-30 Fabio Mazza , Gabriele Ricci , Francesca Colaiori , Stefano Guarino , Sandro Meloni , Fabio Saracco