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Matching cancer patients to clinical trials is essential for advancing treatment and patient care. However, the inconsistent format of medical free text documents and complex trial eligibility criteria make this process extremely…

Predictive analysis is a cornerstone of modern decision-making, with applications in various domains. Large Language Models (LLMs) have emerged as powerful tools in enabling nuanced, knowledge-intensive conversations, thus aiding in complex…

Computation and Language · Computer Science 2025-05-26 Qin Chen , Yuanyi Ren , Xiaojun Ma , Yuyang Shi

Global healthcare providers are exploring use of large language models (LLMs) to provide medical advice to the public. LLMs now achieve nearly perfect scores on medical licensing exams, but this does not necessarily translate to accurate…

Recent advancements in Large Language Models (LLMs) have demonstrated their potential in delivering accurate answers to questions about world knowledge. Despite this, existing benchmarks for evaluating LLMs in healthcare predominantly focus…

Computation and Language · Computer Science 2024-06-18 Zheheng Luo , Chenhan Yuan , Qianqian Xie , Sophia Ananiadou

Current language models (LMs) excel at reasoning over prompts using pre-trained knowledge. However, real-world tasks are far more complex and context-dependent: models must learn from task-specific context and leverage new knowledge beyond…

Large language models (LLMs) are entering clinical workflows as decision support tools, yet how they respond to explicit patient value statements -- the core content of shared decision-making -- remains unmeasured. We conducted a factorial…

Computers and Society · Computer Science 2026-03-03 Sanjay Basu

Clinical diagnosis is a complex reasoning process in which clinicians gather evidence, form hypotheses, and test them against alternative explanations. In medical training, this reasoning is explicitly developed through counterfactual…

Computation and Language · Computer Science 2026-04-24 Zhiwen You , Xi Chen , Aniket Vashishtha , Simo Du , Gabriel Erion-Barner , Hongyuan Mei , Hao Peng , Yue Guo

The proliferation of Large Language Models (LLMs) in high-stakes applications such as medical (self-)diagnosis and preliminary triage raises significant ethical and practical concerns about the effectiveness, appropriateness, and possible…

Computers and Society · Computer Science 2025-06-18 Bonam Mingole , Aditya Majumdar , Firdaus Ahmed Choudhury , Jennifer L. Kraschnewski , Shyam S. Sundar , Amulya Yadav

Large Language Models (LLMs) have achieved remarkable success in general benchmarks, yet their competence in commodity supply chains (CSCs) -- a domain governed by institutional rule systems and feasibility constraints -- remains…

Computation and Language · Computer Science 2026-01-06 Yaxin Cui , Yuanqiang Zeng , Jiapeng Yan , Keling Lin , Kai Ji , Jianhui Zeng , Sheng Zhang , Xin Luo , Binzhu Su , Chaolai Shen , Jiahao Yu

The alignment of large language models (LLMs) with human values is critical for their safe and effective deployment across diverse user populations. However, existing benchmarks often neglect cultural and demographic diversity, leading to…

Computation and Language · Computer Science 2025-09-17 Yao Liang , Dongcheng Zhao , Feifei Zhao , Guobin Shen , Yuwei Wang , Dongqi Liang , Yi Zeng

Large language models (LLMs) provide excellent text-generation capabilities, but standard prompting and generation methods generally do not lead to intentional or goal-directed agents and might necessitate considerable prompt tuning. This…

Computation and Language · Computer Science 2023-12-01 Marwa Abdulhai , Isadora White , Charlie Snell , Charles Sun , Joey Hong , Yuexiang Zhai , Kelvin Xu , Sergey Levine

The rapid rise in popularity of Large Language Models (LLMs) with emerging capabilities has spurred public curiosity to evaluate and compare different LLMs, leading many researchers to propose their own LLM benchmarks. Noticing preliminary…

Artificial Intelligence · Computer Science 2025-05-15 Timothy R. McIntosh , Teo Susnjak , Nalin Arachchilage , Tong Liu , Paul Watters , Malka N. Halgamuge

In this study, we present MedS-Bench, a comprehensive benchmark designed to evaluate the performance of large language models (LLMs) in clinical contexts. Unlike existing benchmarks that focus on multiple-choice question answering,…

Computation and Language · Computer Science 2024-09-06 Chaoyi Wu , Pengcheng Qiu , Jinxin Liu , Hongfei Gu , Na Li , Ya Zhang , Yanfeng Wang , Weidi Xie

Task automation has been greatly empowered by the recent advances in Large Language Models (LLMs) via Python code, where the tasks ranging from software engineering development to general-purpose reasoning. While current benchmarks have…

As large language models (LLMs) develop increasingly sophisticated capabilities and find applications in medical settings, it becomes important to assess their medical safety due to their far-reaching implications for personal and public…

Artificial Intelligence · Computer Science 2024-10-11 Tessa Han , Aounon Kumar , Chirag Agarwal , Himabindu Lakkaraju

Large language models (LLMs) have performed remarkably well in various natural language processing tasks by benchmarking, including in the Western medical domain. However, the professional evaluation benchmarks for LLMs have yet to be…

Computation and Language · Computer Science 2024-06-04 Wenjing Yue , Xiaoling Wang , Wei Zhu , Ming Guan , Huanran Zheng , Pengfei Wang , Changzhi Sun , Xin Ma

In the medical domain, several disease treatment procedures have been documented properly as a set of instructions known as Clinical Practice Guidelines (CPGs). CPGs have been developed over the years on the basis of past treatments, and…

Information Retrieval · Computer Science 2023-08-08 Vasudhan Varma Kandula , Pushpak Bhattacharyya

Large language models (LLMs) are increasingly being used for tasks where outputs shape human decisions, so it is critical to verify that their responses consistently reflect desired human values. Humans, as individuals or groups, don't…

Artificial Intelligence · Computer Science 2026-01-16 Aman Gupta , Denny O'Shea , Fazl Barez

Large Language Models (LLMs) have demonstrated significant potential in decision-making and reasoning, particularly when integrated with various tools to effectively solve complex problems. However, existing benchmarks for evaluating LLMs'…

Current medical language models, adapted from large language models (LLMs), typically predict ICD code-based diagnosis from electronic health records (EHRs) because these labels are readily available. However, ICD codes do not capture the…

Computation and Language · Computer Science 2025-12-09 Wenhao Li , Hongkuan Zhang , Hongwei Zhang , Zhengxu Li , Zengjie Dong , Yafan Chen , Niranjan Bidargaddi , Hong Liu