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The design of genetic networks with specific functions is one of the major goals of synthetic biology. However, constructing biological devices that work "as required" remains challenging, while the cost of uncovering flawed designs…

Systems and Control · Computer Science 2011-11-10 Boyan Yordanov , Calin Belta

The ability of to explain neural network decisions goes hand in hand with their safe deployment. Several methods have been proposed to highlight features important for a given network decision. However, there is no consensus on how to…

Computer Vision and Pattern Recognition · Computer Science 2020-03-23 Agnieszka Grabska-Barwińska

To interpret deep networks, one main approach is to associate neurons with human-understandable concepts. However, existing methods often ignore the inherent relationships of different concepts (e.g., dog and cat both belong to animals),…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Andong Wang , Wei-Ning Lee , Xiaojuan Qi

We present a general information theoretic approach for identifying functional subgraphs in complex networks where the dynamics of each node are observable. We show that the uncertainty in the state of each node can be expressed as a sum of…

Neurons and Cognition · Quantitative Biology 2008-07-31 Luis M. A. Bettencourt , Vadas Gintautas , Michael I. Ham

We propose a new approach to promote safety in classification tasks with established concepts. Our approach -- called a conceptual safeguard -- acts as a verification layer for models that predict a target outcome by first predicting the…

Machine Learning · Computer Science 2024-11-08 Hailey Joren , Charles Marx , Berk Ustun

Recently, deep feedforward neural networks have achieved considerable success in modeling biological sensory processing, in terms of reproducing the input-output map of sensory neurons. However, such models raise profound questions about…

Neurons and Cognition · Quantitative Biology 2019-12-16 Hidenori Tanaka , Aran Nayebi , Niru Maheswaranathan , Lane McIntosh , Stephen A. Baccus , Surya Ganguli

Drawing inspiration from our human brain that designs different neurons for different tasks, recent advances in deep learning have explored modifying a network's neurons to develop so-called task-driven neurons. Prototyping task-driven…

Machine Learning · Computer Science 2026-02-17 Hanyu Pei , Jing-Xiao Liao , Qibin Zhao , Ting Gao , Shijun Zhang , Xiaoge Zhang , Feng-Lei Fan

We show a proof of principle for warping, a method to interpret the inner working of neural networks in the context of gene expression analysis. Warping is an efficient way to gain insight to the inner workings of neural nets and make them…

Genomics · Quantitative Biology 2017-08-17 Trofimov Assya , Lemieux Sebastien , Perreault Claude

Interpretability is crucial for ensuring RL systems align with human values. However, it remains challenging to achieve in complex decision making domains. Existing methods frequently attempt interpretability at the level of fundamental…

Machine Learning · Computer Science 2025-06-03 Anna Soligo , Pietro Ferraro , David Boyle

Neural networks have achieved remarkable success across various fields. However, the lack of interpretability limits their practical use, particularly in critical decision-making scenarios. Post-hoc interpretability, which provides…

Machine Learning · Computer Science 2025-11-21 Yang Ji , Ying Sun , Yuting Zhang , Zhigaoyuan Wang , Yuanxin Zhuang , Zheng Gong , Dazhong Shen , Chuan Qin , Hengshu Zhu , Hui Xiong

Linear classifier probes are frequently utilized to better understand how neural networks function. Researchers have approached the problem of determining unit importance in neural networks by probing their learned, internal…

Machine Learning · Computer Science 2022-11-09 Lucas Hayne , Abhijit Suresh , Hunar Jain , Rahul Kumar , R. McKell Carter

This paper addresses two main challenges facing systems neuroscience today: understanding the nature and function of a) cortical feedback between sensory areas and b) correlated variability. Starting from the old idea of perception as…

Neurons and Cognition · Quantitative Biology 2015-11-20 Ralf M. Haefner , Pietro Berkes , József Fiser

Deep Neural Networks (DNNs) have advanced applications in domains such as healthcare, autonomous systems, and scene understanding, yet the internal semantics of their hidden neurons remain poorly understood. Prior work introduced a Concept…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Moumita Sen Sarma , Samatha Ereshi Akkamahadevi , Pascal Hitzler

We study the problem of explaining a rich class of behavioral properties of deep neural networks. Distinctively, our influence-directed explanations approach this problem by peering inside the network to identify neurons with high influence…

Machine Learning · Computer Science 2018-11-14 Klas Leino , Shayak Sen , Anupam Datta , Matt Fredrikson , Linyi Li

Deep neural networks (DNNs) are the workhorses of deep learning, which constitutes the state of the art in numerous application domains. However, DNN-based decision rules are notoriously prone to poor generalization, i.e., may prove…

Machine Learning · Computer Science 2023-05-11 Guy Amir , Osher Maayan , Tom Zelazny , Guy Katz , Michael Schapira

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

Neurons and Cognition · Quantitative Biology 2020-12-02 Hui Wei

Deep neural networks have demonstrated remarkable performance across various domains, yet their decision-making processes remain opaque. Although many explanation methods are dedicated to bringing the obscurity of DNNs to light, they…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Kanglong Fan , Yunqiao Yang , Chen Ma

A method of discovering how neurons are connected to process information is presented here: Design a simple logic circuit that can perform a single, biologically advantageous function. Engineering concepts can be helpful in choosing the…

Neurons and Cognition · Quantitative Biology 2025-03-07 Lane Yoder

Existing explanation methods for image classification struggle to provide faithful and plausible explanations. This paper addresses this issue by proposing a post-hoc natural language explanation method that can be applied to any CNN-based…

Artificial Intelligence · Computer Science 2025-03-19 Adam Wojciechowski , Mateusz Lango , Ondrej Dusek

Deep neural networks are becoming more and more popular due to their revolutionary success in diverse areas, such as computer vision, natural language processing, and speech recognition. However, the decision-making processes of these…

Computation and Language · Computer Science 2021-10-15 Oana-Maria Camburu