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Trustworthy interpretation of deep learning models is critical for neuroimaging applications, yet commonly used Explainable AI (XAI) methods lack rigorous validation, risking misinterpretation. We performed the first large-scale, systematic…

Machine Learning · Computer Science 2025-08-07 Nys Tjade Siegel , James H. Cole , Mohamad Habes , Stefan Haufe , Kerstin Ritter , Marc-André Schulz

Recent publications have shown that the segmentation accuracy of modern-day convolutional neural networks (CNN) applied on cardiac MRI can reach the inter-expert variability, a great achievement in this area of research. However, despite…

Image and Video Processing · Electrical Eng. & Systems 2020-06-17 Nathan Painchaud , Youssef Skandarani , Thierry Judge , Olivier Bernard , Alain Lalande , Pierre-Marc Jodoin

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Cristiano Patrício , João C. Neves , Luís F. Teixeira

The AI-based assisted diagnosis programs have been widely investigated on medical ultrasound images. Complex scenario of ultrasound image, in which the coupled interference of internal and external factors is severe, brings a unique…

Image and Video Processing · Electrical Eng. & Systems 2025-10-15 Gongping Chen , Lei Zhao , Xiaotao Yin , Liang Cui , Jianxun Zhang , Yu Dai , Ningning Liu

A longstanding challenge surrounding deep learning algorithms is unpacking and understanding how they make their decisions. Explainable Artificial Intelligence (XAI) offers methods to provide explanations of internal functions of algorithms…

Artificial Intelligence · Computer Science 2022-08-16 Amin Nayebi , Sindhu Tipirneni , Brandon Foreman , Chandan K. Reddy , Vignesh Subbian

The use of wearables in medicine and wellness, enabled by AI-based models, offers tremendous potential for real-time monitoring and interpretable event detection. Explainable AI (XAI) is required to assess what models have learned and build…

Signal Processing · Electrical Eng. & Systems 2026-03-16 Maurice Kuschel , Solveig Vieluf , Claus Reinsberger , Tobias Loddenkemper , Tanuj Hasija

Abdominal aortic aneurysms (AAA) pose a significant clinical risk due to their potential for rupture, which is often asymptomatic but can be fatal. Although maximum diameter is commonly used for risk assessment, diameter alone is…

Image and Video Processing · Electrical Eng. & Systems 2025-08-28 Utsav Ratna Tuladhar , Richard Simon , Doran Mix , Michael Richards

Deep learning has been successfully applied to medical image segmentation, enabling accurate identification of regions of interest such as organs and lesions. This approach works effectively across diverse datasets, including those with…

Image and Video Processing · Electrical Eng. & Systems 2025-04-08 Tianyi Ren , Juampablo Heras Rivera , Hitender Oswal , Yutong Pan , Agamdeep Chopra , Jacob Ruzevick , Mehmet Kurt

Accurate segmentation of myocardial lesions from multi-sequence cardiac magnetic resonance imaging is essential for cardiac disease diagnosis and treatment planning. However, achieving optimal feature correspondence is challenging due to…

Image and Video Processing · Electrical Eng. & Systems 2025-07-17 Yifan Gao , Shaohao Rui , Haoyang Su , Jinyi Xiang , Lianming Wu , Xiaosong Wang

In recent years, deep learning has achieved unprecedented success in various computer vision tasks, particularly in object detection. However, the black-box nature and high complexity of deep neural networks pose significant challenges for…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 FatemehSadat Seyedmomeni , Mohammad Ali Keyvanrad

Coronary X-ray angiography is a crucial clinical procedure for the diagnosis and treatment of coronary artery disease, which accounts for roughly 16% of global deaths every year. However, the images acquired in these procedures have low…

Image and Video Processing · Electrical Eng. & Systems 2021-06-23 João Lourenço Silva , Miguel Nobre Menezes , Tiago Rodrigues , Beatriz Silva , Fausto J. Pinto , Arlindo L. Oliveira

In recent years, Artificial Intelligence (AI) has proven its relevance for medical decision support. However, the "black-box" nature of successful AI algorithms still holds back their wide-spread deployment. In this paper, we describe an…

Computer Vision and Pattern Recognition · Computer Science 2021-07-23 Gwenolé Quellec , Hassan Al Hajj , Mathieu Lamard , Pierre-Henri Conze , Pascale Massin , Béatrice Cochener

Deep learning models have achieved impressive performance in medical image segmentation, yet their black-box nature limits clinical adoption. In vascular applications, trustworthy segmentation should rely on both local image cues and global…

Image and Video Processing · Electrical Eng. & Systems 2025-04-17 Guillaume Garret , Antoine Vacavant , Carole Frindel

Advancements in deep learning have enabled highly accurate arrhythmia detection from electrocardiogram (ECG) signals, but limited interpretability remains a barrier to clinical adoption. This study investigates the application of…

Machine Learning · Computer Science 2025-08-26 Joschka Beck , Arlene John

Artificial intelligence (AI) is currently based largely on black-box machine learning models which lack interpretability. The field of eXplainable AI (XAI) strives to address this major concern, being critical in high-stakes areas such as…

Artificial Intelligence · Computer Science 2024-06-26 Sean Tull , Robin Lorenz , Stephen Clark , Ilyas Khan , Bob Coecke

Explainable Artificial Intelligence (XAI) is an emerging research topic of machine learning aimed at unboxing how AI systems' black-box choices are made. This research field inspects the measures and models involved in decision-making and…

Artificial Intelligence · Computer Science 2021-02-04 Guang Yang , Qinghao Ye , Jun Xia

Deep neural networks have become increasingly popular for analyzing ECG data because of their ability to accurately identify cardiac conditions and hidden clinical factors. However, the lack of transparency due to the black box nature of…

Signal Processing · Electrical Eng. & Systems 2024-07-03 Patrick Wagner , Temesgen Mehari , Wilhelm Haverkamp , Nils Strodthoff

Explainable AI (XAI) is an active research area to interpret a neural network's decision by ensuring transparency and trust in the task-specified learned models. Recently, perturbation-based model analysis has shown better interpretation,…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Mahesh Sudhakar , Sam Sattarzadeh , Konstantinos N. Plataniotis , Jongseong Jang , Yeonjeong Jeong , Hyunwoo Kim

Predicting rupture risk and deciding on optimal treatment plan for intracranial aneurysms (IAs) is possible by quantification of their size and shape. For this purpose the IA has to be isolated from 3D angiogram. State-of-the-art methods…

Image and Video Processing · Electrical Eng. & Systems 2020-06-01 Žiga Bizjak , Boštjan Likar , Franjo Pernuš , Žiga Špiclin

Abdominal aortic aneurysm (AAA) is a vascular disease in which a section of the aorta enlarges, weakening its walls and potentially rupturing the vessel. Abdominal ultrasound has been utilized for diagnostics, but due to its limited image…

Image and Video Processing · Electrical Eng. & Systems 2022-08-12 Yordanka Velikova , Walter Simson , Mehrdad Salehi , Mohammad Farid Azampour , Philipp Paprottka , Nassir Navab