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Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

Analyzing vast textual data and summarizing key information from electronic health records imposes a substantial burden on how clinicians allocate their time. Although large language models (LLMs) have shown promise in natural language…

Large language models (LLMs) hold great promise in summarizing medical evidence. Most recent studies focus on the application of proprietary LLMs. Using proprietary LLMs introduces multiple risk factors, including a lack of transparency and…

Large Language Models (LLMs) have been widely applied in various professional fields. By fine-tuning the models using domain specific question and answer datasets, the professional domain knowledge and Q\&A abilities of these models have…

Computation and Language · Computer Science 2024-07-17 Qimin Yang , Rongsheng Wang , Jiexin Chen , Runqi Su , Tao Tan

The recent success of large language models (LLMs) has paved the way for their adoption in the high-stakes domain of healthcare. Specifically, the application of LLMs in patient-trial matching, which involves assessing patient eligibility…

Artificial Intelligence · Computer Science 2023-12-18 Mauro Nievas , Aditya Basu , Yanshan Wang , Hrituraj Singh

Large Language Models (LLMs) have shown promising results on machine translation for high resource language pairs and domains. However, in specialised domains (e.g. medical) LLMs have shown lower performance compared to standard neural…

Computation and Language · Computer Science 2025-07-31 Miguel Rios

Despite significant progress in applying large language models (LLMs) to the medical domain, several limitations still prevent them from practical applications. Among these are the constraints on model size and the lack of cohort-specific…

Artificial Intelligence · Computer Science 2024-09-26 Yishu Wei , Xindi Wang , Hanley Ong , Yiliang Zhou , Adam Flanders , George Shih , Yifan Peng

Fine-tuning large language models (LLMs) with limited data poses a practical challenge in low-resource languages, specialized domains, and constrained deployment settings. While pre-trained LLMs provide strong foundations, effective…

Computation and Language · Computer Science 2025-10-29 Marton Szep , Daniel Rueckert , Rüdiger von Eisenhart-Rothe , Florian Hinterwimmer

This paper presents a pipeline integrating fine-tuned large language models (LLMs) with named entity recognition (NER) for efficient domain-specific text summarization and tagging. The authors address the challenge posed by rapidly evolving…

Computation and Language · Computer Science 2025-10-30 Jun Wang , Fuming Lin , Yuyu Chen

Medical consultation dialogues contain critical clinical information, yet their unstructured nature hinders effective utilization in diagnosis and treatment. Traditional methods, relying on rule-based or shallow machine learning techniques,…

Computation and Language · Computer Science 2025-04-24 Shuguang Zhao , Qiangzhong Feng , Zhiyang He , Peipei Sun , Yingying Wang , Xiaodong Tao , Xiaoliang Lu , Mei Cheng , Xinyue Wu , Yanyan Wang , Wei Liang

We investigate the effectiveness of fine-tuning large language models (LLMs) on small medical datasets for text classification and named entity recognition tasks. Using a German cardiology report dataset and the i2b2 Smoking Challenge…

Computation and Language · Computer Science 2025-03-28 Noah Losch , Lucas Plagwitz , Antonius Büscher , Julian Varghese

The recent success of large language models (LLMs) and the scaling law has led to a widespread adoption of larger models. Particularly in the healthcare industry, there is an increasing demand for locally operated LLMs due to security…

Computation and Language · Computer Science 2024-09-23 Issey Sukeda

Large language models (LLMs) have made significant progress in various domains, including healthcare. However, the specialized nature of clinical language understanding tasks presents unique challenges and limitations that warrant further…

Computation and Language · Computer Science 2023-08-01 Yuqing Wang , Yun Zhao , Linda Petzold

Extracting clinically relevant information from unstructured medical narratives such as admission notes, discharge summaries, and emergency case histories remains a challenge in clinical natural language processing (NLP). Medical Entity…

Artificial Intelligence · Computer Science 2026-04-21 Nwe Ni Win , Jim Basilakis , Steven Thomas , Seyhan Yazar , Laura Pierce , Stephanie Liu , Paul M. Middleton , Nasser Ghadiri , X. Rosalind Wang

Biomedical language understanding benchmarks are the driving forces for artificial intelligence applications with large language model (LLM) back-ends. However, most current benchmarks: (a) are limited to English which makes it challenging…

Computation and Language · Computer Science 2023-10-24 Wei Zhu , Xiaoling Wang , Huanran Zheng , Mosha Chen , Buzhou Tang

Brief hospital course (BHC) summaries are clinical documents that summarize a patient's hospital stay. While large language models (LLMs) depict remarkable capabilities in automating real-world tasks, their capabilities for healthcare…

Large Language Models (LLMs) have demonstrated significant potential in transforming clinical applications. In this study, we investigate the efficacy of four techniques in adapting LLMs for clinical use-cases: continuous pretraining,…

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

Computation and Language · Computer Science 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

Large Language Models (LLMs) have remarkable capabilities across NLP tasks. However, their performance in multilingual contexts, especially within the mental health domain, has not been thoroughly explored. In this paper, we evaluate…

Computation and Language · Computer Science 2026-02-03 Nishat Raihan , Sadiya Sayara Chowdhury Puspo , Ana-Maria Bucur , Stevie Chancellor , Marcos Zampieri

Domain specific large language models are increasingly used to support patient education, triage, and clinical decision making in ophthalmology, making rigorous evaluation essential to ensure safety and accuracy. This study evaluated four…