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Healthcare research and development face significant obstacles due to data scarcity and stringent privacy regulations, such as HIPAA and the GDPR, restricting access to essential real-world medical data. These limitations impede innovation,…

Machine Learning · Computer Science 2025-10-17 Md Ibrahim Shikder Mahin , Md Shamsul Arefin , Md Tanvir Hasan

While deep learning holds great promise for disease diagnosis and prognosis in cardiac magnetic resonance imaging, its progress is often constrained by highly imbalanced and biased training datasets. To address this issue, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Grzegorz Skorupko , Richard Osuala , Zuzanna Szafranowska , Kaisar Kushibar , Vien Ngoc Dang , Nay Aung , Steffen E Petersen , Karim Lekadir , Polyxeni Gkontra

Generally, the small size of public medical imaging datasets coupled with stringent privacy concerns, hampers the advancement of data-hungry deep learning models in medical imaging. This study addresses these challenges for 3D cardiac MRI…

Image and Video Processing · Electrical Eng. & Systems 2024-07-24 Deniz Daum , Richard Osuala , Anneliese Riess , Georgios Kaissis , Julia A. Schnabel , Maxime Di Folco

Human anatomy, morphology, and associated diseases can be studied using medical imaging data. However, access to medical imaging data is restricted by governance and privacy concerns, data ownership, and the cost of acquisition, thus…

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Acquiring images of the same anatomy with multiple different contrasts increases the diversity of diagnostic information available in an MR exam. Yet, scan time limitations may prohibit acquisition of certain contrasts, and images for some…

Computer Vision and Pattern Recognition · Computer Science 2018-02-06 Salman Ul Hassan Dar , Mahmut Yurt , Levent Karacan , Aykut Erdem , Erkut Erdem , Tolga Çukur

Synthetic data generation (SDG) is a promising approach for enabling data sharing in biomedical studies while preserving patient privacy. Yet, state-of-the-art generative models often require large datasets and complex training procedures,…

Machine Learning · Computer Science 2026-01-27 Natalia Espinosa-Dice , Nicholas J. Jackson , Chao Yan , Aaron Lee , Bradley A. Malin

Acquiring annotated data at scale with rare diseases or conditions remains a challenge. It would be extremely useful to have a method that controllably synthesizes images that can correct such underrepresentation. Assuming a proper latent…

Image and Video Processing · Electrical Eng. & Systems 2021-07-06 Spyridon Thermos , Xiao Liu , Alison O'Neil , Sotirios A. Tsaftaris

Image translation across domains for unpaired datasets has gained interest and great improvement lately. In medical imaging, there are multiple imaging modalities, with very different characteristics. Our goal is to use cross-modality…

Image and Video Processing · Electrical Eng. & Systems 2022-02-07 Leo Segre , Or Hirschorn , Dvir Ginzburg , Dan Raviv

The usage of medical image data for the training of large-scale machine learning approaches is particularly challenging due to its scarce availability and the costly generation of data annotations, typically requiring the engagement of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-26 Joshua Niemeijer , Jan Ehrhardt , Hristina Uzunova , Heinz Handels

Cardiac Magnetic Resonance (CMR) imaging provides a comprehensive assessment of cardiac structure and function but remains constrained by high acquisition costs and reliance on expert annotations, limiting the availability of large-scale…

Image and Video Processing · Electrical Eng. & Systems 2026-02-11 Xiaocheng Fang , Zhengyao Ding , Guangkun Nie , Jieyi Cai , Yujie Xiao , Bo Liu , Jiarui Jin , Haoyu Wang , Shun Huang , Ting Chen , Hongyan Li , Shenda Hong

Sharing medical data for machine learning model training purposes is often impossible due to the risk of disclosing identifying information about individual patients. Synthetic data produced by generative artificial intelligence (genAI)…

Machine Learning · Computer Science 2026-02-12 Rustam Zhumagambetov , Niklas Giesa , Sebastian D. Boie , Stefan Haufe

Performing magnetic resonance imaging (MRI) reconstruction from under-sampled k-space data can accelerate the procedure to acquire MRI scans and reduce patients' discomfort. The reconstruction problem is usually formulated as a denoising…

Image and Video Processing · Electrical Eng. & Systems 2023-12-11 Tianqi Xiang , Wenjun Yue , Yiqun Lin , Jiewen Yang , Zhenkun Wang , Xiaomeng Li

Synthetic CT image generation from MRI scan is necessary to create radiotherapy plans without the need of co-registered MRI and CT scans. The chosen baseline adversarial model with cycle consistency permits unpaired image-to-image…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Denis Prokopenko , Joël Valentin Stadelmann , Heinrich Schulz , Steffen Renisch , Dmitry V. Dylov

Generative Adversarial Networks (GANs) have many potential medical imaging applications. Due to the limited memory of Graphical Processing Units (GPUs), most current 3D GAN models are trained on low-resolution medical images, these models…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Mahshid Shiri , Alessandro Bruno , Daniele Loiacono

The generation of privacy-preserving synthetic datasets is a promising avenue for overcoming data scarcity in medical AI research. Post-hoc privacy filtering techniques, designed to remove samples containing personally identifiable…

Machine Learning · Computer Science 2025-10-03 Adil Koeken , Alexander Ziller , Moritz Knolle , Daniel Rueckert

Deep generative models have emerged as a transformative tool in medical imaging, offering substantial potential for synthetic data generation. However, recent empirical studies highlight a critical vulnerability: these models can memorize…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Antonio Scardace , Lemuel Puglisi , Francesco Guarnera , Sebastiano Battiato , Daniele Ravì

Deep learning models for chest X-ray diagnosis are constrained by limited coverage of clinically meaningful concept combinations in publicly available training datasets. While synthetic image generation has been explored to increase data…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

The rapid advancement of Artificial Intelligence (AI) in biomedical imaging and radiotherapy is hindered by the limited availability of large imaging data repositories. With recent research and improvements in denoising diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Rowan Bradbury , Katherine A. Vallis , Bartlomiej W. Papiez

Developing new methods for the automated analysis of clinical fetal and neonatal MRI data is limited by the scarcity of annotated pathological datasets and privacy concerns that often restrict data sharing, hindering the effectiveness of…