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We report theoretical evidence that bulk nonlinear materials weakly interacting with highly localized plasmonic modes in ultra-sub-wavelength metallic nanostructures can lead to nonlinear effects at the single plasmon level in the visible…

Mesoscale and Nanoscale Physics · Physics 2017-04-27 Filippo Alpeggiani , Stefania D'Agostino , Daniele Sanvitto , Dario Gerace

Self-assembly processes allow us to design and create complex nanostructures using molecules as building blocks and surfaces as scaffolds. This autonomous driven construction is possible due to a complex thermodynamic balance of…

Mesoscale and Nanoscale Physics · Physics 2017-09-06 Sabrina Simoncelli , Yi Li , Emiliano Cortés , Stefan A. Maier

The recent demonstration that nanoparticles associated with various biological molecules and pharmacological agents can be administered systemically to humans, without toxicity from the particles, has opened a new era in the targeting of…

Medical Physics · Physics 2007-05-23 G. G. Kenning , R. Rodriguez , V. S. Zotev , A. Moslemi , S. Wilson , L. Hawel , C. Byus , J. S. Kovach

Biosensors based on the principle of surface plasmon resonance (SPR) detection were used to measure biomolecular interactions in sarcomeres and changes of the dielectric constant of tubulin samples with varying concentration. At SPR,…

Quantum Physics · Physics 2015-06-26 Hans A. Schuessler , Alexander A. Kolomenskii , Andreas Mershin , D. V. Nanopoulos

The ability to perform nanometer-scale optical imaging and spectroscopy is key to deciphering the low-energy effects in quantum materials, as well as vibrational fingerprints in planetary and extraterrestrial particles, catalytic…

Molybdenum disulfide, $MoS_2$, is a next-generation semiconductor and is frequently integrated into emergent optoelectronic technologies based on two-dimensional materials. Here, we present a method that provides direct optical feedback on…

The integration of multimodal medical imaging can provide complementary and comprehensive information for the diagnosis of Alzheimer's disease (AD). However, in clinical practice, since positron emission tomography (PET) is often missing,…

Computational Engineering, Finance, and Science · Computer Science 2024-12-03 Fuyou Mao , Lixin Lin , Ming Jiang , Dong Dai , Chao Yang , Hao Zhang , Yan Tang

Accurate early diagnosis and monitoring of neurodegenerative conditions is essential for effective disease management and delivery of medication and treatment. This research develops automatic methods for detecting brain imaging preclinical…

Neural and Evolutionary Computing · Computer Science 2019-10-15 Amir Dehsarvi , Stephen L. Smith

Photonic computing using chalcogenide phase-change materials (PCMs) is under active development for energy-efficient artificial intelligence (AI) applications. A key requirement is to enable as many optically programmable levels per device…

This paper presents a comprehensive study on a novel multilayer surface plasmon resonance (SPR) biosensor designed for detecting trace-level toxins in liquid samples with exceptional precision and efficiency. Leveraging the Kretschmann…

Systems and Control · Electrical Eng. & Systems 2025-01-31 Suripto Bhuiyan , Michael Geller

Quantum sensing with solid-state spin defects has transformed nanoscale metrology, offering sub-wavelength spatial resolution with exceptional sensitivity to multiple signal types. Maximizing these advantages requires minimizing both the…

Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that progressively destroys memory and other cognitive domains of the brain. While effective therapeutic management of AD is still in development, it seems reasonable to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-10 Oleg Michailovich , Rinat Mukhometzianov

Parkinson's disease (PD) is a degenerative and progressive neurological condition. Early diagnosis can improve treatment for patients and is performed through dopaminergic imaging techniques like the SPECT DaTscan. In this study, we propose…

Computer Vision and Pattern Recognition · Computer Science 2020-08-04 Pavan Rajkumar Magesh , Richard Delwin Myloth , Rijo Jackson Tom

Plasmonic devices, fundamental to modern nanophotonics, exploit resonant interactions between light and free electrons in metals to achieve enhanced light trapping and electromagnetic field confinement. However, modeling their complex,…

Computational Engineering, Finance, and Science · Computer Science 2025-08-07 Emmanuel A. Bamidele

Current optical detection schemes for single molecules require light absorption, either to produce fluorescence or direct absorption signals. This severely limits the range of molecules that can be detected, because most molecules are…

Chemical Physics · Physics 2012-07-06 Peter Zijlstra , Pedro M. R. Paulo , Michel Orrit

Self-driven photodetectors (SDPDs) transform photon energy into electrical energy without external voltage, which makes them highly advantageous for applications such as low-power communication and imaging systems. Two-dimensional materials…

Nitroaromatic compounds (NACs) are used in various industrial applications including dyes, inks, herbicides, pharmaceuticals, and explosives. Due to their toxicity and environmental persistence, reliable detection and monitoring methods are…

We report a strong nonlinear optical response of 2D MoSe$_2$ nanoflakes (NFs) through spatial self-phase modulation (SSPM) and cross-phase modulation (XPM) induced by nonlocal coherent light-matter interactions. The coherent interaction of…

We introduce a nanomechanical platform for fast and sensitive measurements of the spectrally-resolved optical dielectric function of 2D materials. At the heart of our approach is a suspended 2D material integrated into a nanomechanical…

Widefield quantum diamond microscopy (WQDM) based on Kohler-illumination has been widely adopted in the field of quantum sensing, however, practical applications are still limited by issues such as unavoidable photodamage and unsatisfied…

Optics · Physics 2023-07-28 Feng Xu , Jialong Chen , Yong Hou , Juan Cheng , Tony KC Hui , Shih-Chi Chen , Zhiqin Chu
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