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Large Language Models (LLMs) have shown promise in clinical applications through prompt engineering, allowing flexible clinical predictions. However, they struggle to produce reliable prediction probabilities, which are crucial for…

Artificial Intelligence · Computer Science 2024-12-05 Bowen Gu , Rishi J. Desai , Kueiyu Joshua Lin , Jie Yang

Large language models (LLMs) can capture rich representations of concepts that are useful for real-world tasks. However, language alone is limited. While existing LLMs excel at text-based inferences, health applications require that models…

Computation and Language · Computer Science 2023-05-26 Xin Liu , Daniel McDuff , Geza Kovacs , Isaac Galatzer-Levy , Jacob Sunshine , Jiening Zhan , Ming-Zher Poh , Shun Liao , Paolo Di Achille , Shwetak Patel

In-hospital mortality (IHM) prediction for ICU patients is critical for timely interventions and efficient resource allocation. While structured physiological data provides quantitative insights, clinical notes offer unstructured,…

Computation and Language · Computer Science 2024-11-27 Harshavardhan Battula , Jiacheng Liu , Jaideep Srivastava

Large Language Models (LLMs) have demonstrated remarkable generalization across diverse tasks, leading individuals to increasingly use them as personal assistants and universal computing engines. Nevertheless, a notable obstacle emerges…

Machine Learning · Computer Science 2023-09-13 Dimitris Spathis , Fahim Kawsar

Large Language Models (LLMs) have emerged as promising recommendation systems, offering novel ways to model user preferences through generative approaches. However, many existing methods often rely solely on text semantics or incorporate…

Machine Learning · Computer Science 2026-01-09 Mir Rayat Imtiaz Hossain , Leo Feng , Leonid Sigal , Mohamed Osama Ahmed

Large language models (LLMs) have demonstrated remarkable capabilities for medical question answering and programming, but their potential for generating interpretable computable phenotypes (CPs) is under-explored. In this work, we…

Machine Learning · Computer Science 2025-08-08 Guilherme Seidyo Imai Aldeia , Daniel S. Herman , William G. La Cava

The deployment of Large Language Models (LLM) on mobile devices offers significant potential for medical applications, enhancing privacy, security, and cost-efficiency by eliminating reliance on cloud-based services and keeping sensitive…

Computation and Language · Computer Science 2025-02-14 Leon Nissen , Philipp Zagar , Vishnu Ravi , Aydin Zahedivash , Lara Marie Reimer , Stephan Jonas , Oliver Aalami , Paul Schmiedmayer

Large Language Models (LLMs) have demonstrated impressive performance in time series analysis and seems to understand the time temporal relationship well than traditional transformer-based approaches. However, since LLMs are not designed…

Machine Learning · Computer Science 2025-05-27 Liangwei Nathan Zheng , Chang George Dong , Wei Emma Zhang , Lin Yue , Miao Xu , Olaf Maennel , Weitong Chen

Large Language Models (LLMs), originally developed for natural language processing (NLP), have demonstrated the potential to generalize across modalities and domains. With their in-context learning (ICL) capabilities, LLMs can perform…

Artificial Intelligence · Computer Science 2025-08-26 Nikolaos Pavlidis , Vasilis Perifanis , Symeon Symeonidis , Pavlos S. Efraimidis

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

The advent of Large Language Models (LLMs) is promising and LLMs have been applied to numerous fields. However, it is not trivial to implement LLMs in the medical field, due to the high standards for precision and accuracy. Currently, the…

Information Retrieval · Computer Science 2024-12-04 Rishabh Goel

The introduction of Large Language Models (LLMs) has advanced data representation and analysis, bringing significant progress in their use for medical questions and answering. Despite these advancements, integrating tabular data, especially…

Computation and Language · Computer Science 2024-09-23 Yanjun Gao , Skatje Myers , Shan Chen , Dmitriy Dligach , Timothy A Miller , Danielle Bitterman , Matthew Churpek , Majid Afshar

Large Language Models (LLMs) have demonstrated promise in medical knowledge assessments, yet their practical utility in real-world clinical decision-making remains underexplored. In this study, we evaluated the performance of three…

Computation and Language · Computer Science 2025-12-30 Mengdi Chai , Ali R. Zomorrodi

Mobile and wearable healthcare monitoring play a vital role in facilitating timely interventions, managing chronic health conditions, and ultimately improving individuals' quality of life. Previous studies on large language models (LLMs)…

Artificial Intelligence · Computer Science 2025-10-01 Xin Wang , Ting Dang , Xinyu Zhang , Vassilis Kostakos , Michael J. Witbrock , Hong Jia

Large language models (LLMs) have achieved remarkable success across various domains, but effectively incorporating complex and potentially noisy user timeline data into LLMs remains a challenge. Current approaches often involve translating…

Computation and Language · Computer Science 2024-09-11 Lin Ning , Luyang Liu , Jiaxing Wu , Neo Wu , Devora Berlowitz , Sushant Prakash , Bradley Green , Shawn O'Banion , Jun Xie

We explore a lightweight framework that adapts frozen large language models to analyze longitudinal clinical data. The approach integrates patient history and context within the language model space to generate accurate forecasts without…

Computation and Language · Computer Science 2025-10-29 Tananun Songdechakraiwut , Michael Lutz

Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

Computation and Language · Computer Science 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

Large language models (LLMs) achieve remarkable performance through ever-increasing parameter counts, but scaling incurs steep computational costs. To better understand LLM scaling, we study representational differences between LLMs and…

Modeling long histories plays a pivotal role in enhancing recommendation systems, allowing to capture user's evolving preferences, resulting in more precise and personalized recommendations. In this study we tackle the challenges of…

Computation and Language · Computer Science 2024-01-11 Sumanth Doddapaneni , Krishna Sayana , Ambarish Jash , Sukhdeep Sodhi , Dima Kuzmin

Training mental health clinicians to conduct standardized clinical assessments is challenging due to a lack of scalable, realistic practice opportunities, which can impact data quality in clinical trials. To address this gap, we introduce a…

Human-Computer Interaction · Computer Science 2025-12-30 Veronica Bossio Botero , Vijay Yadav , Jacob Ouyang , Anzar Abbas , Michelle Worthington