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The increasing adoption of large language models (LLMs) has raised serious concerns about their reliability and trustworthiness. As a result, a growing body of research focuses on evidence-based text generation with LLMs, aiming to link…

Computation and Language · Computer Science 2026-04-17 Tobias Schreieder , Tim Schopf , Michael Färber

Incorporating large language models (LLMs) in medical question answering demands more than high average accuracy: a model that returns substantively different answers each time it is queried is not a reliable medical tool. Online health…

Information Retrieval · Computer Science 2026-04-14 Avi-ad Avraam Buskila

Large Language Models (LLMs) increasingly support applications in a wide range of domains, some with potential high societal impact such as biomedicine, yet their reliability in realistic use cases is under-researched. In this work we…

Large Language Models (LLMs) have made significant progress in various fields. However, challenges remain in Multi-Disciplinary Team (MDT) medical consultations. Current research enhances reasoning through role assignment, task…

Artificial Intelligence · Computer Science 2025-03-19 Kai Chen , Xinfeng Li , Tianpei Yang , Hewei Wang , Wei Dong , Yang Gao

Conversational systems are now capable of producing impressive and generally relevant responses. However, we have no visibility nor control of the socio-emotional strategies behind state-of-the-art Large Language Models (LLMs), which poses…

Computation and Language · Computer Science 2024-12-09 Lorraine Vanel , Ariel R. Ramos Vela , Alya Yacoubi , Chloé Clavel

Efficient knowledge management plays a pivotal role in augmenting both the operational efficiency and the innovative capacity of businesses and organizations. By indexing knowledge through vectorization, a variety of knowledge retrieval…

Computation and Language · Computer Science 2024-04-23 Feihu Jiang , Chuan Qin , Kaichun Yao , Chuyu Fang , Fuzhen Zhuang , Hengshu Zhu , Hui Xiong

Large Language Models (LLMs) have demonstrated impressive capabilities in generating coherent text but often struggle with grounding language and strategic dialogue. To address this gap, we focus on journalistic interviews, a domain rich in…

Computation and Language · Computer Science 2026-02-13 Alexander Spangher , Michael Lu , Sriya Jeslyn Kalyan , Hyundong Justin Cho , Weiyan Shi , Jonathan May

Large Language Models (LLMs) are transforming healthcare through the development of LLM-based agents that can understand, reason about, and assist with medical tasks. This survey provides a comprehensive review of LLM-based agents in…

Computation and Language · Computer Science 2025-05-27 Wenxuan Wang , Zizhan Ma , Zheng Wang , Chenghan Wu , Jiaming Ji , Wenting Chen , Xiang Li , Yixuan Yuan

World models offer a principled framework for simulating future states under interventions, but realizing such models in complex, high-stakes domains like medicine remains challenging. Recent large language models (LLMs) have achieved…

Artificial Intelligence · Computer Science 2026-02-04 Linjie Mu , Zhongzhen Huang , Yannian Gu , Shengqian Qin , Shaoting Zhang , Xiaofan Zhang

There is vivid research on adapting Large Language Models (LLMs) to perform a variety of tasks in high-stakes domains such as healthcare. Despite their popularity, there is a lack of understanding of the extent and contributing factors that…

Computation and Language · Computer Science 2024-06-07 Anand Subramanian , Viktor Schlegel , Abhinav Ramesh Kashyap , Thanh-Tung Nguyen , Vijay Prakash Dwivedi , Stefan Winkler

Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing scenarios, particularly in simulating domain-specific experts using tailored prompts. This ability enables LLMs to adopt the persona of individuals with…

Artificial Intelligence · Computer Science 2025-01-14 Xinyao Ma , Rui Zhu , Zihao Wang , Jingwei Xiong , Qingyu Chen , Haixu Tang , L. Jean Camp , Lucila Ohno-Machado

Recent advancements in large language models (LLMs) have shown promise in generating psychotherapeutic dialogues, particularly in the context of motivational interviewing (MI). However, the inherent lack of transparency in LLM outputs…

Computation and Language · Computer Science 2024-12-18 Xin Sun , Xiao Tang , Abdallah El Ali , Zhuying Li , Pengjie Ren , Jan de Wit , Jiahuan Pei , Jos A. Bosch

In practice, clinicians achieve a diagnosis by following a sequence of steps, such as laboratory exams, observations, or imaging. The pathways to reach diagnosis decisions are documented by guidelines authored by expert organizations, which…

Computation and Language · Computer Science 2024-09-25 Elisa Castagnari , Lillian Muyama , Adrien Coulet

Small and medium-sized enterprises (SMEs) still depend heavily on tacit, experience-based know-how that rarely makes its way into formal documentation. This paper introduces a large-language-model (LLM)-driven conversational assistant that…

Artificial Intelligence · Computer Science 2025-12-08 Unnikrishnan Radhakrishnan

Many AI systems focus solely on providing solutions or explaining outcomes. However, complex tasks like research and strategic thinking often benefit from a more comprehensive approach to augmenting the thinking process rather than…

Human-Computer Interaction · Computer Science 2024-12-25 Soya Park , Hari Subramonyam , Chinmay Kulkarni

The integration of Large Language Models (LLMs) into the healthcare domain has the potential to significantly enhance patient care and support through the development of empathetic, patient-facing chatbots. This study investigates an…

Computation and Language · Computer Science 2024-05-28 Man Luo , Christopher J. Warren , Lu Cheng , Haidar M. Abdul-Muhsin , Imon Banerjee

Patient-trial matching requires reasoning over long, heterogeneous electronic health records (EHRs) and complex eligibility criteria, posing significant challenges for scalability, generalization, and computational efficiency. Existing…

Computation and Language · Computer Science 2026-04-27 Xiaodi Li , Yang Xiao , Munhwan Lee , Konstantinos Leventakos , Young J. Juhn , David Jones , Terence T. Sio , Wei Liu , Maria Vassilaki , Nansu Zong

In the expanding field of language model applications, medical knowledge representation remains a significant challenge due to the specialized nature of the domain. Large language models, such as GPT-4, obtain reasonable scores on medical…

Computation and Language · Computer Science 2024-05-24 Julien Khlaut , Corentin Dancette , Elodie Ferreres , Alaedine Bennani , Paul Hérent , Pierre Manceron

Large language models (LLMs) are increasingly used for medical consultation and health information support. In this high-stakes setting, safety depends not only on medical knowledge, but also on how models respond when patient inputs are…

Computation and Language · Computer Science 2026-04-01 Yahan Li , Xinyi Jie , Wanjia Ruan , Xubei Zhang , Huaijie Zhu , Yicheng Gao , Chaohao Du , Ruishan Liu

This study evaluates the performance of several Large Language Models (LLMs) on MedRedQA, a dataset of consumer-based medical questions and answers by verified experts extracted from the AskDocs subreddit. While LLMs have shown proficiency…

Computation and Language · Computer Science 2025-01-03 Moaiz Abrar , Yusuf Sermet , Ibrahim Demir