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The rapid growth of biomedical knowledge has outpaced our ability to efficiently extract insights and generate novel hypotheses. Large language models (LLMs) have emerged as a promising tool to revolutionize knowledge interaction and…

Computation and Language · Computer Science 2024-07-16 Biqing Qi , Kaiyan Zhang , Kai Tian , Haoxiang Li , Zhang-Ren Chen , Sihang Zeng , Ermo Hua , Hu Jinfang , Bowen Zhou

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

Continuing advances in Large Language Models (LLMs) in artificial intelligence offer important capacities in intuitively accessing and using medical knowledge in many contexts, including education and training as well as assessment and…

Computation and Language · Computer Science 2024-08-01 Roma Shusterman , Allison C. Waters , Shannon O`Neill , Phan Luu , Don M. Tucker

There is a lack of benchmarks for evaluating large language models (LLMs) in long-form medical question answering (QA). Most existing medical QA evaluation benchmarks focus on automatic metrics and multiple-choice questions. While valuable,…

Computation and Language · Computer Science 2024-11-21 Pedram Hosseini , Jessica M. Sin , Bing Ren , Bryceton G. Thomas , Elnaz Nouri , Ali Farahanchi , Saeed Hassanpour

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

Recent advancements in AI have reinvigorated Agent-Based Models (ABMs), as the integration of Large Language Models (LLMs) has led to the emergence of ``generative ABMs'' as a novel approach to simulating social systems. While ABMs offer…

Multiagent Systems · Computer Science 2025-04-07 Maik Larooij , Petter Törnberg

The development of large language models (LLMs) has brought unprecedented possibilities for artificial intelligence (AI) based medical diagnosis. However, the application perspective of LLMs in real diagnostic scenarios is still unclear…

Computation and Language · Computer Science 2024-05-21 Zhoujian Sun , Cheng Luo , Ziyi Liu , Zhengxing Huang

Agent-based simulation is crucial for modeling complex human behavior, yet traditional approaches require extensive domain knowledge and large datasets. In data-scarce healthcare settings where historic and counterfactual data are limited,…

Artificial Intelligence · Computer Science 2025-04-01 Sarah Martinson , Lingkai Kong , Cheol Woo Kim , Aparna Taneja , Milind Tambe

Large Language Models (LLMs) show promise in biomedicine but lack true causal understanding, relying instead on correlations. This paper envisions causal LLM agents that integrate multimodal data (text, images, genomics, etc.) and perform…

Artificial Intelligence · Computer Science 2025-05-23 Adib Bazgir , Amir Habibdoust Lafmajani , Yuwen Zhang

Evidence-based medicine (EBM) is at the forefront of modern healthcare, emphasizing the use of the best available scientific evidence to guide clinical decisions. Due to the sheer volume and rapid growth of medical literature and the high…

Computation and Language · Computer Science 2025-05-29 Zihan Xu , Haotian Ma , Gongbo Zhang , Yihao Ding , Chunhua Weng , Yifan Peng

Electronic health records (EHRs) contain valuable patient data for health-related prediction tasks, such as disease prediction. Traditional approaches rely on supervised learning methods that require large labeled datasets, which can be…

Computation and Language · Computer Science 2024-03-26 Hejie Cui , Zhuocheng Shen , Jieyu Zhang , Hui Shao , Lianhui Qin , Joyce C. Ho , Carl Yang

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

Large language models (LLMs) have demonstrated powerful text generation capabilities, bringing unprecedented innovation to the healthcare field. While LLMs hold immense promise for applications in healthcare, applying them to real clinical…

Computation and Language · Computer Science 2023-10-16 Rui Yang , Edison Marrese-Taylor , Yuhe Ke , Lechao Cheng , Qingyu Chen , Irene Li

Simulation is an invaluable tool for developing and evaluating controllers for self-driving cars. Current simulation frameworks are driven by highly-specialist domain specific languages, and so a natural language interface would greatly…

Artificial Intelligence · Computer Science 2023-10-27 Antonio Valerio Miceli-Barone , Alex Lascarides , Craig Innes

Large language models (LLMs) have demonstrated remarkable performance by following natural language instructions without fine-tuning them on domain-specific tasks and data. However, leveraging LLMs for domain-specific question answering…

Large language models (LLMs) have become increasingly popular in medical domains to assist physicians with a variety of clinical and operational tasks. Given the fast-paced and high-stakes environment of emergency departments (EDs), small…

Computation and Language · Computer Science 2025-10-07 Zirui Wang , Jiajun Wu , Braden Teitge , Jessalyn Holodinsky , Steve Drew

We explore the potential of Large Language Models (LLMs) to assist and potentially correct physicians in medical decision-making tasks. We evaluate several LLMs, including Meditron, Llama2, and Mistral, to analyze the ability of these…

Computation and Language · Computer Science 2024-05-07 Burcu Sayin , Pasquale Minervini , Jacopo Staiano , Andrea Passerini

Interviews are a widely used technique in eliciting requirements to gather stakeholder needs, preferences, and expectations for a software system. Effective interviewing requires skilled interviewers to formulate appropriate interview…

Software Engineering · Computer Science 2025-07-04 Yuchen Shen , Anmol Singhal , Travis Breaux

Open-ended question answering (QA) evaluates a model's ability to perform contextualized reasoning beyond factual recall. This challenge is especially acute in practice-based domains, where knowledge is procedural and grounded in…

Computation and Language · Computer Science 2026-01-29 Si Chen , Le Huy Khiem , Annalisa Szymanski , Ronald Metoyer , Ting Hua , Nitesh V. Chawla