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Engineering synthetic materials that mimic the remarkable complexity of living organisms is a fundamental challenge in science and technology. We study the spatiotemporal patterns that emerge when an active nematicfilm of microtubules and…

Active emulsions and liquid crystalline shells are intriguing and experimentally realisable types of topological matter. Here we numerically study the morphology and spatiotemporal dynamics of a double emulsion, where one or two passive…

We present a generic framework for modelling three-dimensional deformable shells of active matter that captures the orientational dynamics of the active particles and hydrodynamic interactions on the shell and with the surrounding…

Soft Condensed Matter · Physics 2019-11-20 Luuk Metselaar , Julia M. Yeomans , Amin Doostmohammadi

Biological cells can actively tune their intracellular architecture according to their overall shape. Here we explore the rheological implication of such coupling in a minimal model of a dense cellular material where each cell exerts an…

Soft Condensed Matter · Physics 2022-04-13 Shao-Zhen Lin , Matthias Merkel , Jean-François Rupprecht

Morphogenesis of living systems involves topological shape transformations which are highly unusual in the inanimate world. Here we demonstrate that a droplet of a nematic liquid crystal changes its equilibrium shape from a simply-connected…

Soft Condensed Matter · Physics 2023-07-04 Runa Koizumi , Dmitry Golovaty , Ali Alqarni , Bing-Xiang Li , Peter J. Sternberg , Oleg D. Lavrentovich

Using agent-based simulations of self-propelled particles subject to short-range repulsion and nematic alignment we explore the dynamical phases of a dense active material confined to the surface of a sphere. We map the dynamical phase…

Soft Condensed Matter · Physics 2018-04-25 Silke Henkes , M. Cristina Marchetti , Rastko Sknepnek

The topological properties of many materials are central to their behavior, with the dynamics of topological defects being particularly important to intrinsically out-of-equilibrium, active materials. In this paper, local manipulation of…

Soft Condensed Matter · Physics 2019-11-01 David P. Rivas , Tyler N. Shendruk , Robert R. Henry , Daniel H. Reich , Robert L. Leheny

We consider a phase-separating mixture of active and passive fluids and explore morphological asymmetries of the emerging dominantly bicontinous dynamic emulsion. Two-dimensional numerical simulations reveal that the geometric and…

Soft Condensed Matter · Physics 2026-01-22 Rainer Backofen , Axel Voigt

Active forces occurring within cells can drive crucial biological processes that involve spontaneous organization and shape change, such as cell division. Motivated by recent in vitro experiments of nematic droplets of cytoskeletal…

Soft Condensed Matter · Physics 2021-02-16 Fabian Jan Schwarzendahl , Pierre Ronceray , Kimberly L. Weirich , Kinjal Dasbiswas

We study the spatiotemporal patterns that emerge when an active nematic film is topologically constraint. These topological constraints allow to control the non-equilibrium dynamics of the active system. We consider ellipsoidal shapes for…

Soft Condensed Matter · Physics 2017-03-13 Francesco Alaimo , Christian Köhler , Axel Voigt

The emergence of nematic order on deformable closed surfaces plays a pivotal role in the morphogenesis of active biological matter, such as the regeneration of Hydra. In this work, we present a continuum model that couples the…

Soft Condensed Matter · Physics 2026-03-10 Gaetano Napoli , Silvia Paparini

Biological tissues exhibit diverse mechanical and rheological behaviors during morphogenesis. While much is known about tissue phase transitions controlled by structural order and cell mechanics, key questions regarding how tissue-scale…

Soft Condensed Matter · Physics 2026-04-29 Pengyu Yu , Fridtjof Brauns , M. Cristina Marchetti

Topological defects play a prominent role in the physics of two-dimensional materials. When driven out of equilibrium in active nematics, disclinations can acquire spontaneous self-propulsion and drive self-sustained flows upon…

Soft Condensed Matter · Physics 2019-12-06 Suraj Shankar , M. Cristina Marchetti

In pulsating active matter, topological defects are motile despite the absence of any macroscopic flows and microscopic self-propulsion. We reveal that this motility arises from a ratchet effect: the mechanochemical coupling between local…

Soft Condensed Matter · Physics 2026-05-26 Luca Casagrande , Alessandro Manacorda , Etienne Fodor

Morphological trends in growing colonies of living cells are at the core of physiological and evolutionary processes. Using active gel equations, which include cell division, we show that shape changes during the growth can be regulated by…

Soft Condensed Matter · Physics 2016-07-27 Amin Doostmohammadi , Sumesh P. Thampi , Julia M. Yeomans

We present a hydrodynamic model for a thin spherical shell of active nematic liquid crystal with an arbitrary configuration of defects. The active flows generated by defects in the director lead to the formation of stable vortices,…

Soft Condensed Matter · Physics 2017-11-13 Diana Khoromskaia , Gareth P. Alexander

The autonomous motion of liquid crystal oil droplets in micellar media arises from spontaneous breaking of time reversal symmetry via nonlinear coupling between Marangoni stresses and surfactant transport. While this phenomenon has been…

Soft Condensed Matter · Physics 2026-01-15 Salini Kar , Rohit V. Menon , Sanbed Das , Parth Pandya , Sayantan Dutta , Mithun Chowdhury

Active matter is characterized by its ability to induce motion by self-generated stress. In the case of a solid, such motion can lead to shape transformations. The stress-generating components can be anisotropic endowing the material with…

Soft Condensed Matter · Physics 2022-05-16 D. J. G. Pearce , S. Gat , G. Livne , A. Bernheim-Groswasser , K. Kruse

With exquisite precision and reproducibility, cells orchestrate the cooperative action of thousands of nanometer-sized molecular motors to carry out mechanical tasks at much larger length scales, such as cell motility, division and…

Soft Condensed Matter · Physics 2013-01-08 Tim Sanchez , Daniel T. N. Chen , Stephen J. DeCamp , Michael Heymann , Zvonimir Dogic

Active processes drive and guide biological dynamics across scales -- from subcellular cytoskeletal remodelling, through tissue development in embryogenesis, to population-level bacterial colonies expansion. In each of these, biological…

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