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Since its foundations, more than one hundred years ago, the field of structural biology has strived to understand and analyze the properties of molecules and their interactions by studying the structure that they take in 3D space. However,…

Biomolecules · Quantitative Biology 2023-02-27 Gabriele Corso

We introduce the notion of Bartlett spectral measure for isometrically invariant random measures on proper metric commutative spaces. When the underlying Gelfand pair corresponds to a higher-rank, connected, simple matrix Lie group with…

Probability · Mathematics 2025-03-04 Michael Björklund , Mattias Byléhn

We extend the diffusion-map formalism to data sets that are induced by asymmetric kernels. Analytical convergence results of the resulting expansion are proved, and an algorithm is proposed to perform the dimensional reduction. In this work…

Machine Learning · Computer Science 2024-01-24 Alvaro Almeida Gomez , Antonio Silva Neto , Jorge zubelli

Inspired by random walk on graphs, diffusion map (DM) is a class of unsupervised machine learning that offers automatic identification of low-dimensional data structure hidden in a high-dimensional dataset. In recent years, among its many…

Quantum Physics · Physics 2021-11-24 Apimuk Sornsaeng , Ninnat Dangniam , Pantita Palittapongarnpim , Thiparat Chotibut

Temperature estimation, known as thermometry, is a critical sensing task for physical systems operating in the quantum regime. Indeed, thermal fluctuations can significantly degrade quantum coherence. Therefore, accurately determining the…

Diffusion models have achieved great success in image synthesis through iterative noise estimation using deep neural networks. However, the slow inference, high memory consumption, and computation intensity of the noise estimation model…

Computer Vision and Pattern Recognition · Computer Science 2023-06-09 Xiuyu Li , Yijiang Liu , Long Lian , Huanrui Yang , Zhen Dong , Daniel Kang , Shanghang Zhang , Kurt Keutzer

Accurate and efficient prediction of electronic wavefunctions is central to ab initio molecular dynamics (AIMD) and electronic structure theory. However, conventional ab initio methods require self-consistent optimization of electronic…

Chemical Physics · Physics 2025-11-12 Yanxian Tao , Lingyun Wan , Xiongzhi Zeng , Yingdi Jin , Jie Liu , Zhenyu Li , Jinlong Yang

Diffusion Models have become a cornerstone of modern generative AI for their exceptional generation quality and controllability. However, their inherent \textit{multi-step iterations} and \textit{complex backbone networks} lead to…

Effectively designing molecular geometries is essential to advancing pharmaceutical innovations, a domain, which has experienced great attention through the success of generative models and, in particular, diffusion models. However, current…

Biomolecules · Quantitative Biology 2025-01-07 Sirine Ayadi , Leon Hetzel , Johanna Sommer , Fabian Theis , Stephan Günnemann

The introduction of quantum concepts is increasingly making its way into generative machine learning models. However, while there are various implementations of quantum Generative Adversarial Networks, the integration of quantum elements…

In recent years, machine learning models like DALL-E, Craiyon, and Stable Diffusion have gained significant attention for their ability to generate high-resolution images from concise descriptions. Concurrently, quantum computing is showing…

In High Energy Physics simulations play a crucial role in unraveling the complexities of particle collision experiments within CERN's Large Hadron Collider. Machine learning simulation methods have garnered attention as promising…

Data Analysis, Statistics and Probability · Physics 2024-06-06 Mikołaj Kita , Jan Dubiński , Przemysław Rokita , Kamil Deja

Despite recent advancements in latent diffusion models that generate high-dimensional image data and perform various downstream tasks, there has been little exploration into perceptual consistency within these models on the task of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Shreshth Saini , Ru-Ling Liao , Yan Ye , Alan C. Bovik

The field of neural rendering has witnessed significant progress with advancements in generative models and differentiable rendering techniques. Though 2D diffusion has achieved success, a unified 3D diffusion pipeline remains unsettled.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Yushi Lan , Fangzhou Hong , Shangchen Zhou , Shuai Yang , Xuyi Meng , Yongwei Chen , Zhaoyang Lyu , Bo Dai , Xingang Pan , Chen Change Loy

Recent advances in diffusion models have driven remarkable progress in image generation. However, the generation process remains computationally intensive, and users often need to iteratively refine prompts to achieve the desired results,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Yi Wei , Shunpu Tang , Liang Zhao , Qiangian Yang

Using properties of diffusion according to a quantum heat kernel constructed as an expectation over classical heat kernels on $S^1$, we probe the non-manifold-like nature of quantized space in a model of (1+1)-dimensional quantum gravity.…

General Relativity and Quantum Cosmology · Physics 2024-12-18 Elijah Sanderson , Rachel Lash Maitra , AJ Liberatore

In hierarchal order of molecular geometry, we compare the performances of Geometric Quantum Machine Learning models. Two molecular datasets are considered: the simplistic linear shaped LiH-molecule and the trigonal pyramidal molecule NH3.…

Machine Learning · Computer Science 2025-12-08 Saumya Biswas , Jiten Oswal

We studied experimentally the effect of turbulent thermal diffusion in a multi-fan turbulence generator which produces a nearly homogeneous and isotropic flow with a small mean velocity. Using Particle Image Velocimetry and Image Processing…

Fluid Dynamics · Physics 2009-11-11 A. Eidelman , T. Elperin , N. Kleeorin , I. Rogachevskii , I. Sapir-Katiraie

This paper explores image modeling from the frequency space and introduces DCTdiff, an end-to-end diffusion generative paradigm that efficiently models images in the discrete cosine transform (DCT) space. We investigate the design space of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Mang Ning , Mingxiao Li , Jianlin Su , Haozhe Jia , Lanmiao Liu , Martin Beneš , Wenshuo Chen , Albert Ali Salah , Itir Onal Ertugrul

Generating molecules that bind to specific proteins is an important but challenging task in drug discovery. Previous works usually generate atoms in an auto-regressive way, where element types and 3D coordinates of atoms are generated one…

Biomolecules · Quantitative Biology 2024-07-16 Haitao Lin , Yufei Huang , Odin Zhang , Siqi Ma , Meng Liu , Xuanjing Li , Lirong Wu , Jishui Wang , Tingjun Hou , Stan Z. Li