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Fractional factorial designs are widely used for designing screening experiments. Nonregular fractional factorial designs can have better properties than regular designs, but their construction is challenging. Current research on the…

Methodology · Statistics 2021-06-02 Lin Wang , Hongquan Xu

Network coding-based link failure recovery techniques provide near-hitless recovery and offer high capacity efficiency. Diversity coding is the first technique to incorporate coding in this field and is easy to implement over small…

Networking and Internet Architecture · Computer Science 2013-08-12 Serhat Nazim Avci , Ender Ayanoglu

Batch codes serve as critical tools for load balancing in distributed storage systems. While numerous constructions exist for specific batch sizes t, current methodologies predominantly rely on code dimension parameters, limiting their…

Information Theory · Computer Science 2025-04-29 Eldho K. Thomas

Optimal block designs for additive models achieve their efficiency by dividing experimental units among relatively homogenous blocks and allocating treatments equally to blocks. Responses in many modern experiments, however, are drawn from…

Methodology · Statistics 2016-01-05 Stephen Bush , Katya Ruggiero

A Ryser design $\mathcal{D}$ on $v$ points is a collection of $v$ proper subsets (called blocks) of a point-set with $v$ points satisfying (i) every two blocks intersect each other in $\lambda$ points for a fixed $\lambda < v$ (ii) there…

Combinatorics · Mathematics 2019-09-16 Tushar D. Parulekar , Sharad S. Sane

In this work, we consider the Combinatorial RNA Design problem, a minimal instance of the RNA design problem which aims at finding a sequence that admits a given target as its unique base pair maximizing structure. We provide complete…

Quantitative Methods · Quantitative Biology 2015-06-22 Jozef Haleš , Ján Maňuch , Yann Ponty , Ladislav Stacho

The design space for a self-assembled multicomponent objects ranges from a solution in which every building block is unique to one with the minimum number of distinct building blocks that unambiguously define the target structure. Using a…

Soft Condensed Matter · Physics 2023-03-13 Joakim Bohlin , Andrew J. Turberfield , Ard A. Louis , Petr Šulc

We study optimal block designs for comparing a set of test treatments with a control treatment. We provide the class of all E-optimal approximate block designs characterized by simple linear constraints. Employing this characterization, we…

Statistics Theory · Mathematics 2018-04-19 Samuel Rosa

This paper concerns non-overlapping codes, block codes motivated by synchronisation and DNA-based storage applications. Most existing constructions of these codes do not account for the restrictions posed by the physical properties of…

Information Theory · Computer Science 2025-02-05 Lidija Stanovnik , Miha Moškon , Miha Mraz

Augmented designs are typically used in early-stage breeding programs to compare single replicates of test entries by combining them with replicated check varieties. One or two dimensional incomplete blocking can be incorporated in the…

Methodology · Statistics 2025-11-24 E. R. Williams , H-P. Piepho

Design matrices are sparse matrices in which the supports of different columns intersect in a few positions. Such matrices come up naturally when studying problems involving point sets with many collinear triples. In this work we consider…

Combinatorics · Mathematics 2018-03-13 Zeev Dvir , Ankit Garg , Rafael Oliveira , József Solymosi

Distributed systems store data objects redundantly to balance the data access load over multiple nodes. Load balancing performance depends mainly on 1) the level of storage redundancy and 2) the assignment of data objects to storage nodes.…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-12-19 Mehmet Aktas , Emina Soljanin

This manuscript describes the notions of blocker and interdiction applied to well-known optimization problems. The main interest of these two concepts is the capability to analyze the existence of a combinatorial structure after some…

Discrete Mathematics · Computer Science 2024-12-12 Sébastien Martin

Replication is a key technique in the design of efficient and reliable distributed systems. As information grows, it becomes difficult or even impossible to store all information at every replica. A common approach to deal with this problem…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-11-05 Gonçalo Cabrita , Nuno Preguiça

In this article the most fundamental decomposition-based optimization method - block coordinate search, based on the sequential decomposition of problems in subproblems - and building performance simulation programs are used to reason about…

Optimization and Control · Mathematics 2016-09-12 Gian Luca Brunetti

In this paper, we show that for all v\pmod 1 (mod 3), there exists a super- simple (v, 4, 2) directed design. Also, we show that for these parameters there exists a super-simple (v, 4, 2) directed design whose each defining set has at least…

Combinatorics · Mathematics 2015-08-04 M. Boostan , S. Golalizadeh , N. Soltankhah

Compressing resource-intensive large language models by removing whole transformer blocks is a seemingly simple idea, but identifying which blocks to remove constitutes an exponentially difficult combinatorial problem. In this paper, we…

Machine Learning · Computer Science 2026-02-03 David Jansen , Roman Rausch , David Montero , Roman Orus

Block coordinate descent is an optimization paradigm that iteratively updates one block of variables at a time, making it quite amenable to big data applications due to its scalability and performance. Its convergence behavior has been…

Optimization and Control · Mathematics 2023-10-13 Liangzu Peng , René Vidal

Despite considerable progress in genome- and proteome-based high-throughput screening methods and rational drug design, the number of successful single target drugs did not increase appreciably during the past decade. Network models suggest…

Molecular Networks · Quantitative Biology 2007-05-23 Peter Csermely , Vilmos Agoston , Sandor Pongor

Symbolic regression that aims to detect underlying data-driven models has become increasingly important for industrial data analysis. For most existing algorithms such as genetic programming (GP), the convergence speed might be too slow for…

Neural and Evolutionary Computing · Computer Science 2017-10-31 Chen Chen , Changtong Luo , Zonglin Jiang