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Lung cancer remains the leading cause of cancer-related mortality worldwide, with survival strongly dependent on early detection. Standard-dose computed tomography (CT) screening using the Lung Imaging Reporting and Data System (Lung-RADS)…

Radiomics-based AI models show promise for breast cancer diagnosis but often lack interpretability, limiting clinical adoption. This study addresses the gap between radiomic features (RF) and the standardized BI-RADS lexicon by proposing a…

We investigate the connection between visual semantic features defined in PI-RADS and associated risk factors, moving beyond abnormal imaging findings, establishing a shared framework between medical and AI professionals by creating a…

Thyroid cancer is an increasing global health concern that requires advanced diagnostic methods. The application of AI and radiomics to thyroid cancer diagnosis is examined in this review. A review of multiple databases was conducted in…

Purpose: Thyroid cancer has been a common cancer. Papillary thyroid cancer and follicular thyroid cancer are the two most common types of thyroid cancer. Follicular thyroid cancer lacks distinctive ultrasound signs and is more difficult to…

Machine Learning · Computer Science 2025-09-17 Songlin Zhou , Tao Zhou , Xin Li , Stephen Shing-Toung Yau

Objective: Molecular testing (MT) classifies cytologically indeterminate thyroid nodules as benign or malignant with high sensitivity but low positive predictive value (PPV), only using molecular profiles, ignoring ultrasound (US) imaging…

Ultrasound-based risk stratification of thyroid nodules is a critical clinical task, but it suffers from high inter-observer variability. While many deep learning (DL) models function as "black boxes," we propose a fully automated,…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Omar Abdelrazik , Mohamed Elsayed , Noorul Wahab , Nasir Rajpoot , Adam Shephard

Objectives: The purpose is to apply a previously validated deep learning algorithm to a new thyroid nodule ultrasound image dataset and compare its performances with radiologists. Methods: Prior study presented an algorithm which is able to…

Image and Video Processing · Electrical Eng. & Systems 2023-05-08 Jingxi Weng , Benjamin Wildman-Tobriner , Mateusz Buda , Jichen Yang , Lisa M. Ho , Brian C. Allen , Wendy L. Ehieli , Chad M. Miller , Jikai Zhang , Maciej A. Mazurowski

Ultrasound is a useful technique for diagnosing thyroid nodules. Benign and malignant nodules that automatically discriminate in the ultrasound pictures can provide diagnostic recommendations or, improve diagnostic accuracy in the absence…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Ponugoti Nikhila , Sabari Nathan , Elmer Jeto Gomes Ataide , Alfredo Illanes , Michael Friebe , Srichandana Abbineni

Thyroid ultrasound is the first-line exam for assessing thyroid nodules and determining whether biopsy is warranted. In routine reporting, radiologists produce two coupled outputs: a nodule contour for measurement and a TI-RADS risk…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Dina Salama , Mohamed Mahmoud , Nourhan Bayasi , David Liu , Ilker Hacihaliloglu

The ultrasound characteristics of thyroid nodules guide the evaluation of thyroid cancer in patients with thyroid nodules. However, the characteristics of thyroid nodules are often documented in clinical narratives such as ultrasound…

Computation and Language · Computer Science 2023-04-04 Aman Pathak , Zehao Yu , Daniel Paredes , Elio Paul Monsour , Andrea Ortiz Rocha , Juan P. Brito , Naykky Singh Ospina , Yonghui Wu

Purpose: This study investigated how nodule segmentation and surrounding peritumoral regions influence radionics-based lung cancer classification. Methods: Using 3D CT scans with bounding box annotated nodules, we generated 3D segmentations…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Fakrul Islam Tushar

Thyroid cancer is common worldwide, with a rapid increase in prevalence across North America in recent years. While most patients present with palpable nodules through physical examination, a large number of small and medium-sized nodules…

Image and Video Processing · Electrical Eng. & Systems 2020-06-11 Fatemeh Abdolali , Atefeh Shahroudnejad , Abhilash Rakkunedeth Hareendranathan , Jacob L Jaremko , Michelle Noga , Kumaradevan Punithakumar

Ultrasound (US) is the primary imaging technique for the diagnosis of thyroid cancer. However, accurate identification of nodule malignancy is a challenging task that can elude less-experienced clinicians. Recently, many computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Van T. Manh , Jianqiao Zhou , Xiaohong Jia , Zehui Lin , Wenwen Xu , Zihan Mei , Yijie Dong , Xin Yang , Ruobing Huang , Dong Ni

Thyroid disorders are most commonly diagnosed using high-resolution Ultrasound (US). Longitudinal nodule tracking is a pivotal diagnostic protocol for monitoring changes in pathological thyroid morphology. This task, however, imposes a…

Image and Video Processing · Electrical Eng. & Systems 2023-09-04 Lennart Bastian , Vincent Bürgin , Ha Young Kim , Alexander Baumann , Benjamin Busam , Mahdi Saleh , Nassir Navab

An artificial intelligence-generated content-enhanced computer-aided diagnosis (AIGC-CAD) model, designated as ThyGPT, has been developed. This model, inspired by the architecture of ChatGPT, could assist radiologists in assessing the risk…

Computer Vision and Pattern Recognition · Computer Science 2024-02-07 Jincao Yao , Yunpeng Wang , Zhikai Lei , Kai Wang , Xiaoxian Li , Jianhua Zhou , Xiang Hao , Jiafei Shen , Zhenping Wang , Rongrong Ru , Yaqing Chen , Yahan Zhou , Chen Chen , Yanming Zhang , Ping Liang , Dong Xu

Computer-aided diagnosis (CAD) is becoming a prominent approach to assist clinicians spanning across multiple fields. These automated systems take advantage of various computer vision (CV) procedures, as well as artificial intelligence (AI)…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Danilo Avola , Luigi Cinque , Alessio Fagioli , Sebastiano Filetti , Giorgio Grani , Emanuele Rodolà

Purpose: To identify optimal classification methods for computed tomography (CT) radiomics-based preoperative prediction of clear cells renal cell carcinoma (ccRCC) grade. Methods and material: Seventy one ccRCC patients were included in…

Aimed to develop and validate a CT radiomics-based explainable machine learning model for precise diagnosing malignancy and benignity specifically in endometrial cancer (EC) patients. A total of 83 EC patients from two centers, including 46…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Tingrui Zhang , Honglin Wu , Zekun Jiang , Yingying Wang , Rui Ye , Huiming Ni , Chang Liu , Jin Cao , Xuan Sun , Rong Shao , Xiaorong Wei , Yingchun Sun

Ultrasound examination is widely used in the clinical diagnosis of thyroid nodules (benign/malignant). However, the accuracy relies heavily on radiologist experience. Although deep learning techniques have been investigated for thyroid…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Yuchen Wang , Zhongyu Li , Xiangxiang Cui , Liangliang Zhang , Xiang Luo , Meng Yang , Shi Chang
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