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As Large Language Models (LLMs) continue to exhibit increasingly human-like capabilities, aligning them with human values has become critically important. Contemporary advanced techniques, such as prompt learning and reinforcement learning,…

Computation and Language · Computer Science 2025-06-06 Bangde Du , Ziyi Ye , Zhijing Wu , Jankowska Monika , Shuqi Zhu , Qingyao Ai , Yujia Zhou , Yiqun Liu

Recent memory agents improve LLMs by extracting experiences and conversation history into an external storage. This enables low-overhead context assembly and online memory update without expensive LLM training. However, existing solutions…

Artificial Intelligence · Computer Science 2026-02-27 Xinle Wu , Rui Zhang , Mustafa Anis Hussain , Yao Lu

Supervised learning techniques have proven their efficacy in many applications with abundant data. However, applying these methods to medical imaging is challenging due to the scarcity of data, given the high acquisition costs and intricate…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Kevin Arias , Edwin Vargas , Kumar Vijay Mishra , Antonio Ortega , Henry Arguello

While humans naturally learn and adapt from past experiences, large language models (LLMs) and their agentic counterparts struggle to retain reasoning from previous tasks and apply them in future contexts. To address this limitation, we…

Computation and Language · Computer Science 2025-05-21 Peter Baile Chen , Yi Zhang , Dan Roth , Samuel Madden , Jacob Andreas , Michael Cafarella

Most Large Language Model (LLM) agent memory systems rely on a small set of static, hand-designed operations for extracting memory. These fixed procedures hard-code human priors about what to store and how to revise memory, making them…

Computation and Language · Computer Science 2026-05-26 Haozhen Zhang , Quanyu Long , Jianzhu Bao , Tao Feng , Weizhi Zhang , Haodong Yue , Wenya Wang

The rapid growth of medical knowledge and increasing complexity of clinical practice pose challenges. In this context, large language models (LLMs) have demonstrated value; however, inherent limitations remain. Retrieval-augmented…

This paper studies the problem of learning causal structures from observational data. We reformulate the Structural Equation Model (SEM) with additive noises in a form parameterized by binary graph adjacency matrix and show that, if the…

Machine Learning · Computer Science 2022-01-11 Ignavier Ng , Shengyu Zhu , Zhuangyan Fang , Haoyang Li , Zhitang Chen , Jun Wang

Effective memory management is essential for large language model (LLM) agents handling long-term interactions. Current memory frameworks typically treat agents as passive "recorders" and retrieve information without understanding its…

Computation and Language · Computer Science 2026-03-03 Xiaohui Zhang , Zequn Sun , Chengyuan Yang , Yaqin Jin , Yazhong Zhang , Wei Hu

Despite their success, Segment Anything Models (SAMs) experience significant performance drops on severely degraded, low-quality images, limiting their effectiveness in real-world scenarios. To address this, we propose GleSAM, which…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Guangqian Guo , Yong Guo , Xuehui Yu , Wenbo Li , Yaoxing Wang , Shan Gao

Modeling episodic memory (EM) remains a significant challenge in both neuroscience and AI, with existing models either lacking interpretability or struggling with practical applications. This paper proposes the Vision-Language Episodic…

Neurons and Cognition · Quantitative Biology 2025-05-09 Chong Li , Taiping Zeng , Xiangyang Xue , Jianfeng Feng

Evidence-based medicine (EBM) plays a crucial role in the application of large language models (LLMs) in healthcare, as it provides reliable support for medical decision-making processes. Although it benefits from current…

Computation and Language · Computer Science 2025-03-24 Chengfeng Dou , Ying Zhang , Zhi Jin , Wenpin Jiao , Haiyan Zhao , Yongqiang Zhao , Zhengwei Tao

Recent advances in natural language processing (NLP) owe their success to pre-training language models on large amounts of unstructured data. Still, there is an increasing effort to combine the unstructured nature of LMs with structured…

Computation and Language · Computer Science 2023-12-22 Juraj Vladika , Alexander Fichtl , Florian Matthes

Labelling data is expensive and time consuming especially for domains such as medical imaging that contain volumetric imaging data and require expert knowledge. Exploiting a larger pool of labeled data available across multiple centers,…

Computer Vision and Pattern Recognition · Computer Science 2020-09-03 Daiqing Li , Amlan Kar , Nishant Ravikumar , Alejandro F Frangi , Sanja Fidler

As Large Language Model (LLM) agents transition from single-session tools to persistent systems managing longitudinal healthcare journeys, their memory architectures face a critical challenge: reconciling two imperfect sources of truth. The…

Machine Learning · Computer Science 2026-05-01 Samuel L Pugh , Eric Yang , Alexander Muir Sutherland , Alessandra Breschi

To support long-term interaction in complex environments, LLM agents require memory systems that manage historical experiences. Existing approaches either retain full interaction histories via passive context extension, leading to…

Artificial Intelligence · Computer Science 2026-01-30 Jiaqi Liu , Yaofeng Su , Peng Xia , Siwei Han , Zeyu Zheng , Cihang Xie , Mingyu Ding , Huaxiu Yao

Although LLM agents can leverage tools for complex tasks, they still need memory to maintain cross-turn consistency and accumulate reusable information in long-horizon interactions. However, retrieval-based external memory systems incur low…

Artificial Intelligence · Computer Science 2026-04-23 Jiaquan Zhang , Chaoning Zhang , Shuxu Chen , Zhenzhen Huang , Pengcheng Zheng , Zhicheng Wang , Ping Guo , Fan Mo , Sung-Ho Bae , Jie Zou , Jiwei Wei , Yang Yang

Tool-augmented large language model (LLM) agents can orchestrate specialist classifiers, segmentation models, and visual question-answering modules to interpret chest X-rays. However, these agents still solve each case in isolation: they…

Artificial Intelligence · Computer Science 2026-04-17 Weixiang Shen , Bailiang Jian , Jun Li , Che Liu , Johannes Moll , Xiaobin Hu , Daniel Rueckert , Hongwei Bran Li , Jiazhen Pan

Contextually Entangled Gradient Mapping (CEGM) introduces a new approach to gradient optimization, redefining the relationship between contextual embeddings and gradient updates to enhance semantic coherence and reasoning capabilities in…

Machine Learning · Computer Science 2025-08-11 Colin Sisate , Alistair Goldfinch , Vincent Waterstone , Sebastian Kingsley , Mariana Blackthorn

Although self-supervised learning enables us to bootstrap the training by exploiting unlabeled data, the generic self-supervised methods for natural images do not sufficiently incorporate the context. For medical images, a desirable method…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Li Sun , Ke Yu , Kayhan Batmanghelich

Generating clinical reports that summarize abnormal patterns, diagnostic findings, and clinical interpretations from long-term EEG recordings remains labor-intensive. We present CELM, the first clinical EEG-to-Language foundation model…

Machine Learning · Computer Science 2026-05-15 Jathurshan Pradeepkumar , Zheng Chen , Jimeng Sun