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Large Language Models (LLMs) have recently been widely adopted in conversational agents. However, the increasingly long interactions between users and agents accumulate extensive dialogue records, making it difficult for LLMs with limited…

Computation and Language · Computer Science 2025-09-30 Derong Xu , Yi Wen , Pengyue Jia , Yingyi Zhang , wenlin zhang , Yichao Wang , Huifeng Guo , Ruiming Tang , Xiangyu Zhao , Enhong Chen , Tong Xu

Recent work on predicting patient outcomes in the Intensive Care Unit (ICU) has focused heavily on the physiological time series data, largely ignoring sparse data such as diagnoses and medications. When they are included, they are usually…

Machine Learning · Computer Science 2021-01-12 Emma Rocheteau , Catherine Tong , Petar Veličković , Nicholas Lane , Pietro Liò

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

Effective biomedical literature retrieval (BLR) plays a central role in precision medicine informatics. In this paper, we propose GRAPHENE, which is a deep learning based framework for precise BLR. GRAPHENE consists of three main different…

Information Retrieval · Computer Science 2019-11-22 Sendong Zhao , Chang Su , Andrea Sboner , Fei Wang

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

Longitudinal health agents must reason across multi-source trajectories that combine continuous device streams, sparse clinical exams, and episodic life events - yet evaluating them is hard: real-world data cannot be released at scale, and…

Artificial Intelligence · Computer Science 2026-04-06 Chao Li , Cailiang Liu , Ang Gao , Kexin Deng , Shu Zhang , Langping Xu , Xiaotong Shi , Xionghao Ding , Jian Pei , Xun Jiang

Large language models (LLMs) excel at single-turn reasoning but often lose accuracy and coherence over extended, multi-turn interactions. Recent evaluations such as TurnBench highlight recurring failure modes-reasoning bias, task drift,…

Computation and Language · Computer Science 2025-12-17 Yiran Zhang , Jincheng Hu , Mark Dras , Usman Naseem

Large Language Models have demonstrated profound utility in the medical domain. However, their application to autonomous Electronic Health Records~(EHRs) navigation remains constrained by a reliance on curated inputs and simplified…

Computation and Language · Computer Science 2026-01-21 Yusheng Liao , Chuan Xuan , Yutong Cai , Lina Yang , Zhe Chen , Yanfeng Wang , Yu Wang

Large Language Models (LLMs) are increasingly used for clinical decision support, where hallucinations and unsafe suggestions may pose direct risks to patient safety. These risks are hard to assess: subtle clinical errors are often missed…

Computation and Language · Computer Science 2026-05-14 Yinzhu Chen , Abdine Maiga , Hossein A. Rahmani , Emine Yilmaz

Sequential Recommendation System~(SRS) has become pivotal in modern society, which predicts subsequent actions based on the user's historical behavior. However, traditional collaborative filtering-based sequential recommendation models…

Information Retrieval · Computer Science 2025-11-26 Tianjie Dai , Xu Chen , Yunmeng Shu , Jinsong Lan , Xiaoyong Zhu , Jiangchao Yao , Bo Zheng

Human doctors with well-structured medical knowledge can diagnose a disease merely via a few conversations with patients about symptoms. In contrast, existing knowledge-grounded dialogue systems often require a large number of dialogue…

Computation and Language · Computer Science 2020-12-23 Shuai Lin , Pan Zhou , Xiaodan Liang , Jianheng Tang , Ruihui Zhao , Ziliang Chen , Liang Lin

Retrieval-Augmented Generation (RAG) was introduced to enhance the capabilities of Large Language Models (LLMs) beyond their encoded prior knowledge. This is achieved by providing LLMs with an external source of knowledge, which helps…

Computation and Language · Computer Science 2026-03-11 Hazem Amamou , Stéphane Gagnon , Alan Davoust , Anderson R. Avila

LLM-based agents have been widely applied as personal assistants, capable of memorizing information from user messages and responding to personal queries. However, there still lacks an objective and automatic evaluation on their memory…

Artificial Intelligence · Computer Science 2024-10-01 Zeyu Zhang , Quanyu Dai , Luyu Chen , Zeren Jiang , Rui Li , Jieming Zhu , Xu Chen , Yi Xie , Zhenhua Dong , Ji-Rong Wen

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

MLLMs exhibit strong reasoning on isolated queries, yet they operate de novo -- solving each problem independently and often repeating the same mistakes. Existing memory-augmented agents mainly store past trajectories for reuse. However,…

Artificial Intelligence · Computer Science 2026-05-05 Weihao Bo , Shan Zhang , Yanpeng Sun , Jingjing Wu , Qunyi Xie , Xiao Tan , Kunbin Chen , Wei He , Xiaofan Li , Na Zhao , Jingdong Wang , Zechao Li

Self-evolving multi-agent systems (MAS) have emerged as a promising route to LLM agents that continually improve from experience, with persistent memory at their foundation. However, existing designs almost exclusively adopt a centralized…

Multiagent Systems · Computer Science 2026-05-22 Guangya Hao , Yunbo Long , Zhuokai Zhao

Graph-based Retrieval Augmented Generation (GraphRAG) extends retrieval-augmented generation to support structured reasoning over complex corpora, but its reliability under resource-constrained, privacy-sensitive deployments remains…

Computation and Language · Computer Science 2026-05-21 Peter Fernandes , Ria Kanjilal

We focus on a conversational question answering task which combines the challenges of understanding questions in context and reasoning over evidence gathered from heterogeneous sources like text, knowledge graphs, tables, and infoboxes. Our…

Computation and Language · Computer Science 2024-07-16 Parag Jain , Mirella Lapata

We propose a new, training-free method, Graph Reasoning via Retrieval Augmented Framework (GRRAF), that harnesses retrieval-augmented generation (RAG) alongside the code-generation capabilities of large language models (LLMs) to address a…

Artificial Intelligence · Computer Science 2025-09-17 Hanqing Li , Kiran Sheena Jyothi , Henry Liang , Sharika Mahadevan , Diego Klabjan

Advancements in the capabilities of Large Language Models (LLMs) have created a promising foundation for developing autonomous agents. With the right tools, these agents could learn to solve tasks in new environments by accumulating and…

Artificial Intelligence · Computer Science 2025-05-16 Petr Anokhin , Nikita Semenov , Artyom Sorokin , Dmitry Evseev , Andrey Kravchenko , Mikhail Burtsev , Evgeny Burnaev
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