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Imaging airway tissue, optical coherence tomography (OCT) provides cross-sectional images of tissue structures, shows cilia movement and mucus secretion, but does not provide sufficient contrast to differentiate individual cells. By using…

Optical coherence tomography (OCT) is a noninvasive technology that enables real-time imaging of tissue microanatomies. The axial resolution of OCT is intrinsically constrained by the spectral bandwidth of the employed light source while…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Kaiyan Li , Jingyuan Yang , Wenxuan Liang , Xingde Li , Chenxi Zhang , Lulu Chen , Chan Wu , Xiao Zhang , Zhiyan Xu , Yuelin Wang , Lihui Meng , Yue Zhang , Youxin Chen , S. Kevin Zhou

Optical Coherence Tomography is a technique used to scan the Retina of the eye and check for tears. In this paper, we develop a Convolutional Neural Network Architecture for OCT scan classification. The model is trained to detect Retinal…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Adit Magotra , Aagat Gedam , Tanush Savadi , Emily Li

Optical Coherence Tomography (OCT) provides a unique ability to image the eye retina in 3D at micrometer resolution and gives ophthalmologist the ability to visualize retinal diseases such as Age-Related Macular Degeneration (AMD). While…

Computer Vision and Pattern Recognition · Computer Science 2016-10-13 Stefanos Apostolopoulos , Carlos Ciller , Sandro I. De Zanet , Sebastian Wolf , Raphael Sznitman

Allying high-resolution with a large field-of-view (FOV) is of great importance in the fields of biology and medicine, but particularly challenging when imaging non-flat living samples such as the human retina. Indeed, high-resolution is…

With the introduction of spectral-domain optical coherence tomography (OCT), resulting in a significant increase in acquisition speed, the fast and accurate segmentation of 3-D OCT scans has become evermore important. This paper presents a…

Computer Vision and Pattern Recognition · Computer Science 2014-04-01 Fabian Rathke , Stefan Schmidt , Christoph Schnörr

Optical Coherence Tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though OCT offers high…

Medical Physics · Physics 2020-05-29 Cerine Lal , Sergey Alexandrov , Sweta Rani , Yi Zhou , Thomas Ritter , Martin Leahy

Optical coherence tomography (OCT) is a non-invasive imaging technique that can produce images of the eye at the microscopic level. OCT image segmentation to localise retinal layer boundaries is a fundamental procedure for diagnosing and…

Computer Vision and Pattern Recognition · Computer Science 2016-09-09 Jinming Duan , Christopher Tench , Irene Gottlob , Frank Proudlock , Li Bai

We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle. In comparison to current conventional forward looking probe schemes, our approach simplifies the endoscope…

Tracking and localizing objects is a central problem in computer-assisted surgery. Optical coherence tomography (OCT) can be employed as an optical tracking system, due to its high spatial and temporal resolution. Recently, 3D convolutional…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Marcel Bengs , Nils Gessert , Alexander Schlaefer

Automated and accurate segmentation of cystoid structures in Optical Coherence Tomography (OCT) is of interest in the early detection of retinal diseases. It is, however, a challenging task. We propose a novel method for localizing cysts in…

Computer Vision and Pattern Recognition · Computer Science 2017-08-29 Karthik Gopinath , Jayanthi Sivaswamy

Dynamic optical coherence tomography (DOCT) statistically analyzes fluctuations in time-sequential OCT signals, enabling label-free and three-dimensional visualization of intratissue and intracellular activities. Current DOCT methods, such…

Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique that provides high-resolution cross-sectional images of the retina, which are useful for diagnosing and monitoring various retinal diseases. However, manual…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Can Koz , Onat Dalmaz , Mertay Dayanc

Optical coherence tomography (OCT) can perform non-invasive high-resolution three-dimensional (3D) imaging and has been widely used in biomedical fields, while it is inevitably affected by coherence speckle noise which degrades OCT imaging…

Optics · Physics 2025-06-30 Renxiong Wu , Fei Zheng , Meixuan Li , Shaoyan Huang , Xin Ge , Linbo Liu , Yong Liu , Guangming Ni

Speckle is an intrinsic pattern in optical coherence tomography (OCT) that obscures fine image features and degrades effective resolution. In this study, we propose a numerical speckle reduction method based on the dispersed scatterer model…

Optical Coherence Tomography Angiography (OCTA) is a non-invasive and non-contacting imaging technique providing visualization of microvasculature of retina and optic nerve head in human eyes in vivo. The adequate image quality of OCTA is…

Image and Video Processing · Electrical Eng. & Systems 2021-07-23 Yufei Wang , Yiqing Shen , Meng Yuan , Jing Xu , Bin Yang , Chi Liu , Wenjia Cai , Weijing Cheng , Wei Wang

Optical coherence tomography (OCT) is a 3D imaging technique that was introduced in 1991 [Science 254, 1178 (1991); Applied Optics 31, 919 (1992)]. Since 2018 there has been growing interest in a new type of OCT scheme based on the use of…

Computational corrections of defocus and aberrations in optical coherence tomography (OCT) offers a promising approach to realize high-resolution imaging with deep imaging depth, but without additional high hardware costs. However, these…

Optics · Physics 2025-10-28 Shuichi Makita , Naoki Fukutake , Lida Zhu , Yoshiaki Yasuno

Optical diffraction tomography (ODT) is a three-dimensional (3D) quantitative phase imaging technique, which enables the reconstruction of the 3D refractive index (RI) distribution of a transparent sample. Due to its fast, non-invasive, and…

Optics · Physics 2018-11-14 Chansuk Park , Seungwoo Shin , Yongkeun Park

Optical Coherence Tomography Angiography (OCTA) is a crucial tool in the clinical screening of retinal diseases, allowing for accurate 3D imaging of blood vessels through non-invasive scanning. However, the hardware-based approach for…

Image and Video Processing · Electrical Eng. & Systems 2024-08-22 Shuhan Li , Dong Zhang , Xiaomeng Li , Chubin Ou , Lin An , Yanwu Xu , Kwang-Ting Cheng