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Diffusion Transformers (DiTs) have demonstrated strong performance in generative modeling, particularly in image synthesis, making them a compelling choice for molecular conformer generation. However, applying DiTs to molecules introduces…

Machine Learning · Computer Science 2025-11-12 J. Thorben Frank , Winfried Ripken , Gregor Lied , Klaus-Robert Müller , Oliver T. Unke , Stefan Chmiela

Developing embodied AI agents requires scalable training environments that balance content diversity with physics accuracy. World simulators provide such environments but face distinct limitations: video-based methods generate diverse…

In this report, we introduce UltraShape 1.0, a scalable 3D diffusion framework for high-fidelity 3D geometry generation. The proposed approach adopts a two-stage generation pipeline: a coarse global structure is first synthesized and then…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Tanghui Jia , Dongyu Yan , Dehao Hao , Yang Li , Kaiyi Zhang , Xianyi He , Lanjiong Li , Yuhan Wang , Jinnan Chen , Lutao Jiang , Qishen Yin , Long Quan , Ying-Cong Chen , Li Yuan

Molecular representation learning has shown great success in advancing AI-based drug discovery. The core of many recent works is based on the fact that the 3D geometric structure of molecules provides essential information about their…

Machine Learning · Computer Science 2024-10-23 Jiying Zhang , Zijing Liu , Yu Wang , Yu Li

We present HY-Motion 1.0, a series of state-of-the-art, large-scale, motion generation models capable of generating 3D human motions from textual descriptions. HY-Motion 1.0 represents the first successful attempt to scale up Diffusion…

State-of-the-art vessel segmentation methods typically require large-scale annotated datasets and suffer from severe performance degradation under domain shifts. In clinical practice, however, acquiring extensive annotations for every new…

Image and Video Processing · Electrical Eng. & Systems 2026-03-02 Kirato Yoshihara , Yohei Sugawara , Yuta Tokuoka , Lihang Hong

Diffusion models have significantly advanced the fields of image, audio, and video generation, but they depend on an iterative sampling process that causes slow generation. To overcome this limitation, we propose consistency models, a new…

Machine Learning · Computer Science 2023-06-01 Yang Song , Prafulla Dhariwal , Mark Chen , Ilya Sutskever

Molecular dynamics (MD) has long been the de facto choice for simulating complex atomistic systems from first principles. Recently deep learning models become a popular way to accelerate MD. Notwithstanding, existing models depend on…

Computational Engineering, Finance, and Science · Computer Science 2023-01-10 Fang Wu , Stan Z. Li

Current unified multimodal models for image generation and editing typically rely on massive parameter scales (e.g., >10B), entailing prohibitive training costs and deployment footprints. In this work, we present DeepGen 1.0, a lightweight…

This paper delves into the study of 3D point cloud reconstruction from a single image. Our objective is to develop the Consistency Diffusion Model, exploring synergistic 2D and 3D priors in the Bayesian framework to ensure superior…

Computer Vision and Pattern Recognition · Computer Science 2025-02-03 Chenru Jiang , Chengrui Zhang , Xi Yang , Jie Sun , Yifei Zhang , Bin Dong , Kaizhu Huang

We present Seed3D 2.0, an advanced 3D content generation system built on Seed3D 1.0, with substantial improvements across generation fidelity, simulation-ready capabilities, and application coverage. For geometry, a coarse-to-fine two-stage…

Pre-trained on extensive and diverse multi-modal datasets, 2D foundation models excel at addressing 2D tasks with little or no downstream supervision, owing to their robust representations. The emergence of 2D-to-3D distillation frameworks…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Anas Mahmoud , Ali Harakeh , Steven Waslander

Notable breakthroughs in diffusion modeling have propelled rapid improvements in video generation, yet current foundational model still face critical challenges in simultaneously balancing prompt following, motion plausibility, and visual…

One major branch of saliency object detection methods is diffusion-based which construct a graph model on a given image and diffuse seed saliency values to the whole graph by a diffusion matrix. While their performance is sensitive to…

Computer Vision and Pattern Recognition · Computer Science 2020-01-20 Peng Jiang , Zhiyi Pan , Nuno Vasconcelos , Baoquan Chen , Jingliang Peng

Extensively exploring protein conformational landscapes remains a major challenge in computational biology due to the high computational cost involved in dynamic physics-based simulations. In this work, we propose a novel pipeline, MoDyGAN,…

Machine Learning · Computer Science 2025-07-21 Jingbo Liang , Bruna Jacobson

Billions of organic molecules are known, but only a tiny fraction of the functional inorganic materials have been discovered, a particularly relevant problem to the community searching for new quantum materials. Recent advancements in…

In this work, we present SupResDiffGAN, a novel hybrid architecture that combines the strengths of Generative Adversarial Networks (GANs) and diffusion models for super-resolution tasks. By leveraging latent space representations and…

Image and Video Processing · Electrical Eng. & Systems 2025-04-21 Dawid Kopeć , Wojciech Kozłowski , Maciej Wizerkaniuk , Dawid Krutul , Jan Kocoń , Maciej Zięba

Robust local feature representations are essential for spatial intelligence tasks such as robot navigation and augmented reality. Establishing reliable correspondences requires descriptors that provide both high discriminative power and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Haodi Yao , Fenghua He , Ning Hao , Yao Su

Fast and accurate generation of molecular conformers is desired for downstream computational chemistry and drug discovery tasks. Currently, training and sampling state-of-the-art diffusion or flow-based models for conformer generation…

Sparse-view 3D modeling represents a fundamental tension between reconstruction fidelity and generative plausibility. While feed-forward reconstruction excels in efficiency and input alignment, it often lacks the global priors needed for…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Zhisheng Huang , Jiahao Chen , Cheng Lin , Chenyu Hu , Hanzhuo Huang , Zhengming Yu , Mengfei Li , Yuheng Liu , Zekai Gu , Zibo Zhao , Yuan Liu , Xin Li , Wenping Wang
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