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Deep learning has emerged as a strong alternative for classical iterative methods for deformable medical image registration, where the goal is to find a mapping between the coordinate systems of two images. Popular classical image…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Joel Honkamaa , Pekka Marttinen

The alignment of serial-section electron microscopy (ssEM) images is critical for efforts in neuroscience that seek to reconstruct neuronal circuits. However, each ssEM plane contains densely packed structures that vary from one section to…

Computer Vision and Pattern Recognition · Computer Science 2017-12-06 Inwan Yoo , David G. C. Hildebrand , Willie F. Tobin , Wei-Chung Allen Lee , Won-Ki Jeong

Deformable image registration is a crucial step in medical image analysis for finding a non-linear spatial transformation between a pair of fixed and moving images. Deep registration methods based on Convolutional Neural Networks (CNNs)…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Mingyuan Meng , Lei Bi , Dagan Feng , Jinman Kim

Deformable image registration (DIR) is a crucial and challenging technique for aligning anatomical structures in medical images and is widely applied in diverse clinical applications. However, existing approaches often struggle to capture…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Shayan Kebriti , Shahabedin Nabavi , Ali Gooya

To accurately analyze changes of anatomical structures in longitudinal imaging studies, consistent segmentation across multiple time-points is required. Existing solutions often involve independent registration and segmentation components.…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Bo Li , Wiro Niessen , Stefan Klein , Marius de Groot , Arfan Ikram , Meike Vernooij , Esther Bron

In this work we propose a deep learning network for deformable image registration (DIRNet). The DIRNet consists of a convolutional neural network (ConvNet) regressor, a spatial transformer, and a resampler. The ConvNet analyzes a pair of…

Computer Vision and Pattern Recognition · Computer Science 2017-12-08 Bob D. de Vos , Floris F. Berendsen , Max A. Viergever , Marius Staring , Ivana Išgum

Image registration, the process of aligning two or more images, is the core technique of many (semi-)automatic medical image analysis tasks. Recent studies have shown that deep learning methods, notably convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2021-09-09 Bob D. de Vos , Floris F. Berendsen , Max A. Viergever , Hessam Sokooti , Marius Staring , Ivana Isgum

The advent of deep-learning-based registration networks has addressed the time-consuming challenge in traditional iterative methods.However, the potential of current registration networks for comprehensively capturing spatial relationships…

Computer Vision and Pattern Recognition · Computer Science 2024-02-15 Zhuoyuan Wang , Haiqiao Wang , Yi Wang

Recent successes in deep learning based deformable image registration (DIR) methods have demonstrated that complex deformation can be learnt directly from data while reducing computation time when compared to traditional methods. However,…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Sharib Ali , Jens Rittscher

Unsupervised deep learning is a promising method in brain MRI registration to reduce the reliance on anatomical labels, while still achieving anatomically accurate transformations. For the Learn2Reg2024 LUMIR challenge, we propose…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Lukas Förner , Kartikay Tehlan , Thomas Wendler

Deformable image registration poses a challenging problem where, unlike most deep learning tasks, a complex relationship between multiple coordinate systems has to be considered. Although data-driven methods have shown promising…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Vasiliki Sideri-Lampretsa , Nil Stolt-Ansó , Huaqi Qiu , Julian McGinnis , Wenke Karbole , Martin Menten , Daniel Rueckert

Decoding brain states from functional magnetic resonance imaging (fMRI) data is vital for advancing neuroscience and clinical applications. While traditional machine learning and deep learning approaches have made strides in leveraging the…

Machine Learning · Computer Science 2025-12-10 Danial Jafarzadeh Jazi , Maryam Hajiesmaeili

Accurate registration of brain MRI scans is fundamental for cross-subject analysis in neuroscientific studies. This involves aligning both the cortical surface of the brain and the interior volume. Traditional methods treat volumetric and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-24 S. Mazdak Abulnaga , Andrew Hoopes , Malte Hoffmann , Robin Magnet , Maks Ovsjanikov , Lilla Zöllei , John Guttag , Bruce Fischl , Adrian Dalca

Deformable image registration (alignment) is highly sought after in numerous clinical applications, such as computer aided diagnosis and disease progression analysis. Deep Convolutional Neural Network (DCNN)-based image registration methods…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Ruizhe Li , Grazziela Figueredo , Dorothee Auer , Christian Wagner , Xin Chen

Most of the deep learning based medical image registration algorithms focus on brain image registration tasks.Compared with brain registration, the chest CT registration has larger deformation, more complex background and region over-lap.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Cheng Wang , Qiyu Gao , Fandong Zhang , Shu Zhang , Yizhou Yu

Rigid registration aims to determine the translations and rotations necessary to align features in a pair of images. While recent machine learning methods have become state-of-the-art for linear and deformable registration across subjects,…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Jingru Fu , Adrian V. Dalca , Bruce Fischl , Rodrigo Moreno , Malte Hoffmann

Image registration and in particular deformable registration methods are pillars of medical imaging. Inspired by the recent advances in deep learning, we propose in this paper, a novel convolutional neural network architecture that couples…

Computer Vision and Pattern Recognition · Computer Science 2018-09-18 Stergios Christodoulidis , Mihir Sahasrabudhe , Maria Vakalopoulou , Guillaume Chassagnon , Marie-Pierre Revel , Stavroula Mougiakakou , Nikos Paragios

Purpose: This study aims to explore training strategies to improve convolutional neural network-based image-to-image deformable registration for abdominal imaging. Methods: Different training strategies, loss functions, and transfer…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Javier Pérez de Frutos , André Pedersen , Egidijus Pelanis , David Bouget , Shanmugapriya Survarachakan , Thomas Langø , Ole-Jakob Elle , Frank Lindseth

Deep learning technologies have dramatically reshaped the field of medical image registration over the past decade. The initial developments, such as regression-based and U-Net-based networks, established the foundation for deep learning in…

Image and Video Processing · Electrical Eng. & Systems 2024-11-04 Junyu Chen , Yihao Liu , Shuwen Wei , Zhangxing Bian , Shalini Subramanian , Aaron Carass , Jerry L. Prince , Yong Du

Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans essential. Conventional DIR methods are often too slow for…