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We develop a new computing paradigm, which we refer to as data-driven computing, according to which calculations are carried out directly from experimental material data and pertinent constraints and conservation laws, such as compatibility…

Computational Physics · Physics 2016-04-20 Trenton Kirchdoerfer , Michael Ortiz

Vision Transformers (ViTs) excel in 3D medical segmentation but require massive annotated datasets. While Self-Supervised Learning (SSL) mitigates this using unlabeled data, it still faces strict privacy and logistical barriers.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Jiaqi Tang , Mengyan Zheng , Shu Zhang , Fandong Zhang , Qingchao Chen

The System-by-Design (SbD) is an emerging engineering framework for the optimization-driven design of complex electromagnetic (EM) devices and systems. More specifically, the computational complexity of the design problem at hand is…

Signal Processing · Electrical Eng. & Systems 2022-02-16 Andrea Massa , Marco Salucci

Given that observational and numerical climate data are being produced at ever more prodigious rates, increasingly sophisticated and automated analysis techniques have become essential. Deep learning is quickly becoming a standard approach…

Fluid Dynamics · Physics 2017-09-12 A. Rupe , J. P. Crutchfield , K. Kashinath , Prabhat

Data-driven design is making headway into a number of application areas, including protein, small-molecule, and materials engineering. The design goal is to construct an object with desired properties, such as a protein that binds to a…

Machine Learning · Computer Science 2025-04-04 Clara Fannjiang , Jennifer Listgarten

Machine learning (ML) is transforming modern physics research, but practical, hands-on experience with ML techniques remains limited due to cost and complexity barriers. To address this gap, we introduce an affordable, autonomous,…

Physics Education · Physics 2026-04-16 Yang Liu , Qianjie Lei , Xiaolong He , Yizhe Xue , Kexin He , Haitao Yang , Yong Wang , Xian Zhang , Li Yang , Yichun Zhou , Ruiqi Hu , Yong Xie

A ''technology lottery'' describes a research idea or technology succeeding over others because it is suited to the available software and hardware, not necessarily because it is superior to alternative directions--examples abound, from the…

Artificial Intelligence · Computer Science 2022-11-10 Erik Peterson , Alexander Lavin

Conventional navigation pipelines for legged robots remain largely geometry-centric, relying on dense SLAM representations that are fragile under rapid motion and offer limited support for semantic decision making in open-world exploration.…

Robotics · Computer Science 2026-03-09 Guoyang Zhao , Yudong Li , Weiqing Qi , Kai Zhang , Bonan Liu , Kai Chen , Haoang Li , Jun Ma

Self-driving laboratories have begun to replace human experimenters in performing single experimental skills or predetermined experimental protocols. However, as the pace of idea iteration in scientific research has been intensified by…

Artificial Intelligence · Computer Science 2025-04-08 Yu-Zhe Shi , Mingchen Liu , Fanxu Meng , Qiao Xu , Zhangqian Bi , Kun He , Lecheng Ruan , Qining Wang

Engineering superlattices (SLs) - which are spatially periodic potential landscapes for electrons - is an emerging approach for the realization of exotic properties, including superconductivity and correlated insulators, in two-dimensional…

Mesoscale and Nanoscale Physics · Physics 2024-12-19 Vinay Kammarchedu , Derrick Butler , Asmaul Smitha Rashid , Aida Ebrahimi , Morteza Kayyalha

Structure-based drug design (SBDD) aims to design small-molecule ligands that bind with high affinity and specificity to pre-determined protein targets. Generative SBDD methods leverage structural data of drugs in complex with their protein…

Despite the extensive usage of oxide glasses for a few millennia, the composition-property relationships in these materials still remain poorly understood. While empirical and physics-based models have been used to predict properties, these…

Radical progress in the field of deep learning (DL) has led to unprecedented accuracy in diverse inference tasks. As such, deploying DL models across mobile platforms is vital to enable the development and broad availability of the…

Machine Learning · Computer Science 2021-06-10 Stylianos I. Venieris , Ioannis Panopoulos , Iakovos S. Venieris

Cellular solids and micro-lattices are a class of lightweight architected materials that have been established for their unique mechanical, thermal, and acoustic properties. It has been shown that by tuning material architecture, a…

Materials Science · Physics 2024-03-12 Shengzhi Luan , Enze Chen , Joel John , Stavros Gaitanaros

Artificial intelligence (AI) has the potential to transform healthcare by supporting more accurate diagnoses and personalized treatments. However, its adoption in practice remains constrained by fragmented data sources, strict privacy…

Software Engineering · Computer Science 2026-02-16 Mira Raheem , Amal Elgammal , Michael Papazoglou , Bernd Krämer , Neamat El-Tazi

I propose a novel framework that integrates stochastic differential equations (SDEs) with deep generative models to improve uncertainty quantification in machine learning applications involving structured and temporal data. This approach,…

Machine Learning · Statistics 2026-01-09 James Rice

Materials discovery and design are essential for advancing technology across various industries by enabling the development of application-specific materials. Recent research has leveraged Large Language Models (LLMs) to accelerate this…

Computation and Language · Computer Science 2025-02-11 Shrinidhi Kumbhar , Venkatesh Mishra , Kevin Coutinho , Divij Handa , Ashif Iquebal , Chitta Baral

A main challenge in mechanical design is to efficiently explore the design space while satisfying engineering constraints. This work explores the use of 3D generative models to explore the design space in the context of vehicle development,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Hayata Morita , Kohei Shintani , Chenyang Yuan , Frank Permenter

We propose to adopt a declarative domain specific language for describing the physics algorithm of a high energy physics (HEP) analysis in a standard and unambiguous way decoupled from analysis software frameworks, and argue that this…

High Energy Physics - Phenomenology · Physics 2022-03-21 Harrison B. Prosper , Sezen Sekmen , Gokhan Unel

Advancements in scientific instrument sensors and connected devices provide unprecedented insight into ongoing experiments and present new opportunities for control, optimization, and steering. However, the diversity of sensors and…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-04 Jakob R. Elias , Ryan Chard , Maksim Levental , Zhengchun Liu , Ian Foster , Santanu Chaudhuri
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