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Bayesian optimization (BO) has gained attention as an efficient algorithm for black-box optimization of expensive-to-evaluate systems, where the BO algorithm iteratively queries the system and suggests new trials based on a probabilistic…

Machine Learning · Computer Science 2026-03-13 Eike Cramer , Luis Kutschat , Oliver Stollenwerk , Joel A. Paulson , Alexander Mitsos

AI-powered autonomous experimentation (AI/AE) can accelerate materials discovery but its effectiveness for electronic materials is hindered by data scarcity from lengthy and complex design-fabricate-test-analyze cycles. Unlike experienced…

The reliable operation of modern power grids requires probabilistic load forecasts with well-calibrated uncertainty estimates. However, existing deep learning models produce overconfident point predictions that fail catastrophically under…

Machine Learning · Computer Science 2026-03-10 Sajib Debnath , Md. Uzzal Mia

Algorithmic trading relies on machine learning models to make trading decisions. Despite strong in-sample performance, these models often degrade when confronted with evolving real-world market regimes, which can shift dramatically due to…

Machine Learning · Computer Science 2026-01-27 Haochong Xia , Simin Li , Ruixiao Xu , Zhixia Zhang , Hongxiang Wang , Zhiqian Liu , Teng Yao Long , Molei Qin , Chuqiao Zong , Bo An

We present a novel multi-stage workflow for computational materials discovery that achieves a 99% success rate in identifying compounds within 100 meV/atom of thermodynamic stability, with a threefold improvement over previous approaches.…

Heterogeneous materials, crucial in various engineering applications, exhibit complex multiscale behavior, which challenges the effectiveness of traditional computational methods. In this work, we introduce the Micromechanics Transformer…

Computational Engineering, Finance, and Science · Computer Science 2024-10-10 Sifan Wang , Tong-Rui Liu , Shyam Sankaran , Paris Perdikaris

Thermochemical energy storage (TCES) based on salt hydrates is a promising route for seasonal heat storage; however, the design of practical sorbent materials remains challenging due to a non-trivial coupling between composition, synthesis…

One of the recent approaches used to minimize the impacts of the growth of impermeable areas in urban centers is permeable flooring. Permeable floors can be made of concrete and are called permeable concrete. This research aims to analyze…

Applied Physics · Physics 2022-04-29 Rebeca de M. Kich , Victor A. Kich , Kelvin I. Seibt

Machine learning can significantly improve performance for decision-making under uncertainty across a wide range of domains. However, ensuring robustness guarantees requires well-calibrated uncertainty estimates, which can be difficult to…

Machine Learning · Computer Science 2026-02-03 Christopher Yeh , Nicolas Christianson , Alan Wu , Adam Wierman , Yisong Yue

Knowing a biomolecule's structure is inherently linked to and a prerequisite for any detailed understanding of its function. Significant effort has gone into developing technologies for structural characterization. These technologies do not…

Data Structures and Algorithms · Computer Science 2017-06-22 Michael Wegner , Oskar Taubert , Alexander Schug , Henning Meyerhenke

Bayesian optimization is highly effective for optimizing expensive-to-evaluate black-box functions, but it faces significant computational challenges due to the cubic per-iteration cost of Gaussian processes, which results in a total time…

Optimization and Control · Mathematics 2026-05-21 Tansheng Zhu , Hongyu Zhou , Ke Jin , Xusheng Xu , Qiufan Yuan , Lijie Ji

The clustering of bounded data presents unique challenges in statistical analysis due to the constraints imposed on the data values. This paper introduces a novel method for model-based clustering specifically designed for bounded data.…

Methodology · Statistics 2025-05-16 Luca Scrucca

Accurate force fields are essential for reliable molecular simulations. These models are refined against quantum mechanical calculations and experimental measurements, which are subject to random and systematic errors. Bayesian Inference of…

Chemical Physics · Physics 2025-11-04 Robert M. Raddi , Vincent A. Voelz

Bipartite learning is a machine learning task that aims to predict interactions between pairs of instances. It has been applied to various domains, including drug-target interactions, RNA-disease associations, and regulatory network…

Machine Learning · Computer Science 2025-11-18 Pedro Ilídio , Felipe Kenji Nakano , Alireza Gharahighehi , Robbe D'hondt , Ricardo Cerri , Celine Vens

Modern software is increasingly built by composing APIs, elevating the API contract to a critical role. Inadequate contracts, however, lead to mismatched expectations and failures, creating a pressing need for robust conformance testing.…

Software Engineering · Computer Science 2025-10-23 S M Sadrul Islam Asif , James Chen , Earl T. Barr , Mark Marron

Bayesian Optimization (BO) links Gaussian Process (GP) surrogates with sequential design toward optimizing expensive-to-evaluate black-box functions. Example design heuristics, or so-called acquisition functions, like expected improvement…

Machine Learning · Computer Science 2023-08-16 Ryan B. Christianson , Robert B. Gramacy

Objective: Brain-machine interfaces (BMIs) aim to provide direct brain control of devices such as prostheses and computer cursors, which have demonstrated great potential for mobility restoration. One major limitation of current BMIs lies…

Machine Learning · Computer Science 2022-04-27 Yu Qi , Xinyun Zhu , Kedi Xu , Feixiao Ren , Hongjie Jiang , Junming Zhu , Jianmin Zhang , Gang Pan , Yueming Wang

A large component of the building material concrete consists of aggregate with varying particle sizes between 0.125 and 32 mm. Its actual size distribution significantly affects the quality characteristics of the final concrete in both, the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-31 Max Coenen , Dries Beyer , Christian Heipke , Michael Haist

Bayes additive regression trees(BART) is a nonparametric regression model which has gained wide-spread popularity in recent years due to its flexibility and high accuracy of estimation. Soft BART,one variation of BART,improves both…

Machine Learning · Statistics 2023-10-24 Hao Ran , Yang Bai

Bayesian optimisation is a sample-efficient search methodology that holds great promise for accelerating drug and materials discovery programs. A frequently-overlooked modelling consideration in Bayesian optimisation strategies however, is…

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