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Thyroid nodule classification and segmentation in ultrasound images are crucial for computer-aided diagnosis; however, they face limitations owing to insufficient labeled data. In this study, we proposed a multi-view contrastive…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Jian Wang , Xin Yang , Xiaohong Jia , Wufeng Xue , Rusi Chen , Yanlin Chen , Xiliang Zhu , Lian Liu , Yan Cao , Jianqiao Zhou , Dong Ni , Ning Gu

Artificial intelligence based radiomics models for thyroid ultrasound (US) often achieve strong diagnostic performance but remain difficult to interpret, limiting clinical trust and adoption. We developed and validated an interpretable…

Ultrasound-based risk stratification of thyroid nodules is a critical clinical task, but it suffers from high inter-observer variability. While many deep learning (DL) models function as "black boxes," we propose a fully automated,…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Omar Abdelrazik , Mohamed Elsayed , Noorul Wahab , Nasir Rajpoot , Adam Shephard

Thyroid cancer is the most common endocrine malignancy, and accurately distinguishing between benign and malignant thyroid tumors is crucial for developing effective treatment plans in clinical practice. Pathologically, thyroid tumors pose…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Jia Dong , Yao Yao , Yang Dong , Hui Ma

Objectives: The purpose is to apply a previously validated deep learning algorithm to a new thyroid nodule ultrasound image dataset and compare its performances with radiologists. Methods: Prior study presented an algorithm which is able to…

Image and Video Processing · Electrical Eng. & Systems 2023-05-08 Jingxi Weng , Benjamin Wildman-Tobriner , Mateusz Buda , Jichen Yang , Lisa M. Ho , Brian C. Allen , Wendy L. Ehieli , Chad M. Miller , Jikai Zhang , Maciej A. Mazurowski

Over the past decades, the incidence of thyroid cancer has been increasing globally. Accurate and early diagnosis allows timely treatment and helps to avoid over-diagnosis. Clinically, a nodule is commonly evaluated from both transverse and…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Han Huang , Yijie Dong , Xiaohong Jia , Jianqiao Zhou , Dong Ni , Jun Cheng , Ruobing Huang

Automatic radiology report generation has attracted enormous research interest due to its practical value in reducing the workload of radiologists. However, simultaneously establishing global correspondences between the image (e.g., Chest…

Computer Vision and Pattern Recognition · Computer Science 2023-07-19 Yaowei Li , Bang Yang , Xuxin Cheng , Zhihong Zhu , Hongxiang Li , Yuexian Zou

Thyroid nodule classification using ultrasound imaging is essential for early diagnosis and clinical decision-making; however, despite promising performance on in-distribution data, existing deep learning methods often exhibit limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Yangmei Chen , Zhongyuan Zhang , Xikun Zhang , Xinyu Hao , Mingliang Hou , Renqiang Luo , Ziqi Xu

Thyroid nodule classification aims at determining whether the nodule is benign or malignant based on a given ultrasound image. However, the label obtained by the cytological biopsy which is the golden standard in clinical medicine is not…

Computer Vision and Pattern Recognition · Computer Science 2022-07-05 Haifan Gong , Hui Cheng , Yifan Xie , Shuangyi Tan , Guanqi Chen , Fei Chen , Guanbin Li

Introduction: Deep learning-based segmentation models are increasingly integrated into clinical imaging workflows, yet their robustness to adversarial perturbations remains incompletely characterized, particularly for ultrasound images. We…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Nicholas Dietrich , David McShannon

Ultrasound (US) is the primary imaging technique for the diagnosis of thyroid cancer. However, accurate identification of nodule malignancy is a challenging task that can elude less-experienced clinicians. Recently, many computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Van T. Manh , Jianqiao Zhou , Xiaohong Jia , Zehui Lin , Wenwen Xu , Zihan Mei , Yijie Dong , Xin Yang , Ruobing Huang , Dong Ni

Thyroid cancer is a common endocrine carcinoma that occurs in the thyroid gland. Much effort has been invested in improving its diagnosis, and thyroidectomy remains the primary treatment method. A successful operation without unnecessary…

Machine Learning · Computer Science 2022-03-31 Nan Miles Xi , Lin Wang , Chuanjia Yang

Radiology reports for the same patient examination may contain clinically meaningful discrepancies arising from interpretation differences, reporting variability, or evolving assessments. Systematic analysis of such discrepancies is…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Zhaoyi Sun , Minal Jagtiani , Wen-wai Yim , Fei Xia , Martin Gunn , Meliha Yetisgen , Asma Ben Abacha

Machine learning (ML) for diagnosis of thyroid nodules on ultrasound is an active area of research. However, ML tools require large, well-labelled datasets, the curation of which is time-consuming and labor-intensive. The purpose of our…

Image and Video Processing · Electrical Eng. & Systems 2023-05-05 Jikai Zhang , Maciej M. Mazurowski , Brian C. Allen , Benjamin Wildman-Torbiner

Computer-aided diagnosis (CAD) is becoming a prominent approach to assist clinicians spanning across multiple fields. These automated systems take advantage of various computer vision (CV) procedures, as well as artificial intelligence (AI)…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Danilo Avola , Luigi Cinque , Alessio Fagioli , Sebastiano Filetti , Giorgio Grani , Emanuele Rodolà

Thyroid nodule segmentation is a crucial step in the diagnostic procedure of physicians and computer-aided diagnosis systems. Mostly, current studies treat segmentation and diagnosis as independent tasks without considering the correlation…

Image and Video Processing · Electrical Eng. & Systems 2023-08-30 Weihua Liu , Chaochao Lin

Segmentation of nodules in thyroid ultrasound imaging plays a crucial role in the detection and treatment of thyroid cancer. However, owing to the diversity of scanner vendors and imaging protocols in different hospitals, the automatic…

Image and Video Processing · Electrical Eng. & Systems 2024-01-23 Xuewei Li , Yaqiao Zhu , Jie Gao , Xi Wei , Ruixuan Zhang , Yuan Tian , ZhiQiang Liu

Purpose: Thyroid cancer has been a common cancer. Papillary thyroid cancer and follicular thyroid cancer are the two most common types of thyroid cancer. Follicular thyroid cancer lacks distinctive ultrasound signs and is more difficult to…

Machine Learning · Computer Science 2025-09-17 Songlin Zhou , Tao Zhou , Xin Li , Stephen Shing-Toung Yau

Accurate medical image analysis can greatly assist clinical diagnosis, but its effectiveness relies on high-quality expert annotations Obtaining pixel-level labels for medical images, particularly fundus images, remains costly and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Xi Luo , Shixin Xu , Ying Xie , JianZhong Hu , Yuwei He , Yuhui Deng , Huaxiong Huang

Objective: Molecular testing (MT) classifies cytologically indeterminate thyroid nodules as benign or malignant with high sensitivity but low positive predictive value (PPV), only using molecular profiles, ignoring ultrasound (US) imaging…

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