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We evaluate two different methods for the integration of prediction uncertainty into diagnostic image classifiers to increase patient safety in deep learning. In the first method, Monte Carlo sampling is applied with dropout at test time to…
Deep neural networks (DNN) have achieved great success in image restoration. However, most DNN methods are designed as a black box, lacking transparency and interpretability. Although some methods are proposed to combine traditional…
Monitoring of Diffuse Intrinsic Pontine Glioma (DIPG) and Diffuse Midline Glioma (DMG) brain tumors in pediatric patients is key for assessment of treatment response. Response Assessment in Pediatric Neuro-Oncology (RAPNO) guidelines…
Deep learning techniques have successfully been employed in numerous computer vision tasks including image segmentation. The techniques have also been applied to medical image segmentation, one of the most critical tasks in computer-aided…
When employing deep neural networks (DNNs) for semantic segmentation in safety-critical applications like automotive perception or medical imaging, it is important to estimate their performance at runtime, e.g. via uncertainty estimates or…
Brain tumors are increasingly prevalent, characterized by the uncontrolled spread of aberrant tissues in the brain, with almost 700,000 new cases diagnosed globally each year. Magnetic Resonance Imaging (MRI) is commonly used for the…
Quality control (QC) of MR images is essential to ensure that downstream analyses such as segmentation can be performed successfully. Currently, QC is predominantly performed visually and subjectively, at significant time and operator cost.…
Convolutional neural networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they have not demonstrated sufficiently accurate and robust results for clinical use. In addition, they are…
Collecting annotations from multiple independent sources could mitigate the impact of potential noises and biases from a single source, which is a common practice in medical image segmentation. Learning segmentation networks from…
Automated diagnosis with artificial intelligence has emerged as a promising area in the realm of medical imaging, while the interpretability of the introduced deep neural networks still remains an urgent concern. Although contemporary…
Tumor region segmentation is an essential task for the quantitative analysis of digital pathology. Recently presented deep neural networks have shown state-of-the-art performance in various image-segmentation tasks. However, because of the…
Organ at risk (OAR) segmentation is a crucial step for treatment planning and outcome determination in radiotherapy treatments of cancer patients. Several deep learning based segmentation algorithms have been developed in recent years,…
One of the common issues in clinical decision-making is the presence of uncertainty, which often arises due to ambiguity in radiology reports, which often reflect genuine diagnostic uncertainty or limitations of automated label extraction…
Uncertainty estimation in deep learning has become a leading research field in medical image analysis due to the need for safe utilisation of AI algorithms in clinical practice. Most approaches for uncertainty estimation require sampling…
Machine-based brain tumor segmentation can help doctors make better diagnoses. However, the complex structure of brain tumors and expensive pixel-level annotations present challenges for automatic tumor segmentation. In this paper, we…
Automatic segmentation is essential for the brain tumor diagnosis, disease prognosis, and follow-up therapy of patients with gliomas. Still, accurate detection of gliomas and their sub-regions in multimodal MRI is very challenging due to…
Intracranial tumors are groups of cells that usually grow uncontrollably. One out of four cancer deaths is due to brain tumors. Early detection and evaluation of brain tumors is an essential preventive medical step that is performed by…
In this paper, we present a fully automatic brain tumor segmentation method based on Deep Neural Networks (DNNs). The proposed networks are tailored to glioblastomas (both low and high grade) pictured in MR images. By their very nature,…
Gliomas are the most common and aggressive among brain tumors, which cause a short life expectancy in their highest grade. Therefore, treatment assessment is a key stage to enhance the quality of the patients' lives. Recently, deep…
We consider the problem of uncertainty estimation in the context of (non-Bayesian) deep neural classification. In this context, all known methods are based on extracting uncertainty signals from a trained network optimized to solve the…