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The development of generative models in the past decade has allowed for hyperrealistic data synthesis. While potentially beneficial, this synthetic data generation process has been relatively underexplored in cancer histopathology. One…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Aakash Madhav Rao , Debayan Gupta

Scientific measurements are often bottlenecked by suboptimal conditions, whether that be noise, incomplete spatial coverage, or limited resolution, rendering accurate field reconstruction a difficult task. We introduce LatentPDE, a latent…

Machine Learning · Computer Science 2026-04-28 Valerie Tsao , Nathaniel Chaney , Manolis Veveakis

Generative models serve as powerful tools for modeling the real world, with mainstream diffusion models, particularly those based on the latent diffusion model paradigm, achieving remarkable progress across various tasks, such as image and…

Machine Learning · Computer Science 2025-02-04 Wanghan Xu , Xiaoyu Yue , Zidong Wang , Yao Teng , Wenlong Zhang , Xihui Liu , Luping Zhou , Wanli Ouyang , Lei Bai

Latent diffusion models (LDMs) achieve state-of-the-art performance across various tasks, including image generation and video synthesis. However, they generally lack robustness, a limitation that remains not fully explored in current…

Machine Learning · Computer Science 2025-06-10 Boris Martirosyan , Alexey Karmanov

Adversarial attacks are a central tool for probing the robustness of modern vision models, yet most methods optimize perturbations directly in pixel space under $\ell_\infty$ or $\ell_2$ constraints. While effective in white-box settings,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Eitan Shaar , Ariel Shaulov , Yalcin Tur , Gal Chechik , Ravid Shwartz-Ziv

Latent variable models such as the Variational Auto-Encoder (VAE) have become a go-to tool for analyzing biological data, especially in the field of single-cell genomics. One remaining challenge is the interpretability of latent variables…

Genomics · Quantitative Biology 2023-02-20 Romain Lopez , Nataša Tagasovska , Stephen Ra , Kyunghyn Cho , Jonathan K. Pritchard , Aviv Regev

Estimation of uncertainty in deep learning models is of vital importance, especially in medical imaging, where reliance on inference without taking into account uncertainty could lead to misdiagnosis. Recently, the probabilistic Variational…

Machine Learning · Computer Science 2020-10-20 Haleh Akrami , Anand A. Joshi , Sergul Aydore , Richard M. Leahy

In this paper we tackle a fundamental question: "Can we train latent diffusion models together with the variational auto-encoder (VAE) tokenizer in an end-to-end manner?" Traditional deep-learning wisdom dictates that end-to-end training is…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Xingjian Leng , Jaskirat Singh , Yunzhong Hou , Zhenchang Xing , Saining Xie , Liang Zheng

Current state-of-the-art generative approaches frequently rely on a two-stage training procedure, where an autoencoder (often a VAE) first performs dimensionality reduction, followed by training a generative model on the learned latent…

Machine Learning · Statistics 2025-07-15 Gianluigi Silvestri , Luca Ambrogioni

We present Qwen-Image-VAE-2.0, a suite of high-compression Variational Autoencoders (VAEs) that achieve significant advances in both reconstruction fidelity and diffusability. To address the reconstruction bottlenecks of high compression,…

Variational autoencoders (VAEs) and generative adversarial networks (GANs) enjoy an intuitive connection to manifold learning: in training the decoder/generator is optimized to approximate a homeomorphism between the data distribution and…

Machine Learning · Computer Science 2020-08-28 Henry Li , Ofir Lindenbaum , Xiuyuan Cheng , Alexander Cloninger

Once deployed, medical image analysis methods are often faced with unexpected image corruptions and noise perturbations. These unknown covariate shifts present significant challenges to deep learning based methods trained on "clean" images.…

Machine Learning · Computer Science 2025-07-01 Xing Shen , Hengguan Huang , Brennan Nichyporuk , Tal Arbel

The recent use of diffusion prior, enhanced by pre-trained text-image models, has markedly elevated the performance of image super-resolution (SR). To alleviate the huge computational cost required by pixel-based diffusion SR, latent-based…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Feng Luo , Jinxi Xiang , Jun Zhang , Xiao Han , Wei Yang

Variational autoencoders (VAEs), one of the most widely used generative models, are known to suffer from posterior collapse, a phenomenon that reduces the diversity of generated samples. To avoid posterior collapse, many prior works have…

Machine Learning · Computer Science 2025-08-19 Hyunsoo Song , Seungwhan Kim , Seungkyu Lee

We consider the problem of lossy image compression with deep latent variable models. State-of-the-art methods build on hierarchical variational autoencoders (VAEs) and learn inference networks to predict a compressible latent representation…

Image and Video Processing · Electrical Eng. & Systems 2021-01-11 Yibo Yang , Robert Bamler , Stephan Mandt

Latent space is one of the key concepts in generative AI, offering powerful means for creative exploration through vector manipulation. However, diffusion models like Stable Diffusion lack the intuitive latent vector control found in GANs,…

Machine Learning · Computer Science 2025-09-29 Zhihua Zhong , Xuanyang Huang

Diffusion models face a fundamental trade-off between generation quality and computational efficiency. Latent Diffusion Models (LDMs) offer an efficient solution but suffer from potential information loss and non-end-to-end training. In…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Zhennan Chen , Junwei Zhu , Xu Chen , Jiangning Zhang , Xiaobin Hu , Hanzhen Zhao , Chengjie Wang , Jian Yang , Ying Tai

Variational Autoencoders (VAEs) provide a theoretically-backed and popular framework for deep generative models. However, learning a VAE from data poses still unanswered theoretical questions and considerable practical challenges. In this…

Machine Learning · Computer Science 2020-06-01 Partha Ghosh , Mehdi S. M. Sajjadi , Antonio Vergari , Michael Black , Bernhard Schölkopf

The performance of Latent Diffusion Models (LDMs) is critically dependent on the quality of their visual tokenizers. While recent works have explored incorporating Vision Foundation Models (VFMs) into the tokenizers training via…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Tianci Bi , Xiaoyi Zhang , Yan Lu , Nanning Zheng

Recent advances in Latent Video Diffusion Models (LVDMs) have revolutionized video generation by leveraging Video Variational Autoencoders (Video VAEs) to compress intricate video data into a compact latent space. However, as LVDM training…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Yu Cheng , Fajie Yuan
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