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In this work, we perform unsupervised learning of representations by maximizing mutual information between an input and the output of a deep neural network encoder. Importantly, we show that structure matters: incorporating knowledge about…

Predicting whether a treatment leads to meaningful improvement is a central challenge in personalized medicine, particularly when disease progression manifests as subtle visual changes over time. While data-driven deep learning (DL) offers…

Image and Video Processing · Electrical Eng. & Systems 2025-11-21 Jana Armouti , Nikhil Madaan , Rohan Panda , Tom Fox , Laura Hutchins , Amita Krishnan , Ricardo Rodriguez , Bennett DeBoisblanc , Deva Ramanan , John Galeotti , Gautam Gare

Massive data collection holds the promise of a better understanding of complex phenomena and, ultimately, better decisions. Representation learning has become a key driver of deep learning applications, as it allows learning latent spaces…

Machine Learning · Computer Science 2025-11-10 Caroline Uhler , Jiaqi Zhang

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

Self-supervised pretraining followed by supervised fine-tuning has seen success in image recognition, especially when labeled examples are scarce, but has received limited attention in medical image analysis. This paper studies the…

Pre-training has shown success in different areas of machine learning, such as Computer Vision, Natural Language Processing (NLP), and medical imaging. However, it has not been fully explored for clinical data analysis. An immense amount of…

Machine Learning · Computer Science 2023-07-18 Chantal Pellegrini , Nassir Navab , Anees Kazi

Self-supervised representation learning on image-text data facilitates crucial medical applications, such as image classification, visual grounding, and cross-modal retrieval. One common approach involves contrasting semantically similar…

Machine Learning · Computer Science 2023-08-15 Peiqi Wang , Yingcheng Liu , Ching-Yun Ko , William M. Wells , Seth Berkowitz , Steven Horng , Polina Golland

Clinical machine learning models are increasingly trained using large scale, multimodal foundation paradigms, yet deployment environments often differ systematically from the data generating settings used during training. Such shifts arise…

Machine Learning · Computer Science 2026-03-10 Yuanyun Zhang , Shi Li

Longitudinal imaging is capable of capturing the static ana\-to\-mi\-cal structures and the dynamic changes of the morphology resulting from aging or disease progression. Self-supervised learning allows to learn new representation from…

Image and Video Processing · Electrical Eng. & Systems 2019-10-25 Antoine Rivail , Ursula Schmidt-Erfurth , Wolf-Dieter Vogl , Sebastian M. Waldstein , Sophie Riedl , Christoph Grechenig , Zhichao Wu , Hrvoje Bogunović

We present a new self-supervised pre-training of Vision Transformers for dense prediction tasks. It is based on a contrastive loss across views that compares pixel-level representations to global image representations. This strategy…

Computer Vision and Pattern Recognition · Computer Science 2022-06-08 Jaonary Rabarisoa , Valentin Belissen , Florian Chabot , Quoc-Cuong Pham

In self-supervised learning, a system is tasked with achieving a surrogate objective by defining alternative targets on a set of unlabeled data. The aim is to build useful representations that can be used in downstream tasks, without costly…

Machine Learning · Computer Science 2020-11-11 Massimiliano Patacchiola , Amos Storkey

To extract robust deep representations from long sequential modeling of speech data, we propose a self-supervised learning approach, namely Contrastive Separative Coding (CSC). Our key finding is to learn such representations by separating…

Audio and Speech Processing · Electrical Eng. & Systems 2021-03-02 Jun Wang , Max W. Y. Lam , Dan Su , Dong Yu

Self-supervised learning of deep neural networks has become a prevalent paradigm for learning representations that transfer to a variety of downstream tasks. Similar to proposed models of the ventral stream of biological vision, it is…

Machine Learning · Computer Science 2023-06-26 Kion Fallah , Alec Helbling , Kyle A. Johnsen , Christopher J. Rozell

Representation learning constitutes a pivotal cornerstone in contemporary deep learning paradigms, offering a conduit to elucidate distinctive features within the latent space and interpret the deep models. Nevertheless, the inherent…

Computer Vision and Pattern Recognition · Computer Science 2024-02-07 Siyuan Dai , Kai Ye , Kun Zhao , Ge Cui , Haoteng Tang , Liang Zhan

In comparison to classical shallow representation learning techniques, deep neural networks have achieved superior performance in nearly every application benchmark. But despite their clear empirical advantages, it is still not well…

Machine Learning · Computer Science 2022-01-11 Calvin Murdock , George Cazenavette , Simon Lucey

High-quality representation of transactional sequences is vital for modern banking applications, including risk management, churn prediction, and personalized customer offers. Different tasks require distinct representation properties:…

Machine Learning · Computer Science 2024-12-24 Aleksandr Yugay , Alexey Zaytsev

In recent years self-supervised learning has emerged as a promising candidate for unsupervised representation learning. In the visual domain its applications are mostly studied in the context of images of natural scenes. However, its…

Computer Vision and Pattern Recognition · Computer Science 2021-06-04 Vladan Stojnić , Vladimir Risojević

Recent methods in self-supervised learning have demonstrated that masking-based pretext tasks extend beyond NLP, serving as useful pretraining objectives in computer vision. However, existing approaches apply random or ad hoc masking…

Computer Vision and Pattern Recognition · Computer Science 2022-12-19 Dylan Sam , Min Bai , Tristan McKinney , Li Erran Li

Limited availability of labeled physiological data often prohibits the use of powerful supervised deep learning models in the biomedical machine intelligence domain. We approach this problem and propose a novel encoding framework that…

Machine Learning · Computer Science 2023-06-13 Philipp Hallgarten , David Bethge , Ozan Özdenizci , Tobias Grosse-Puppendahl , Enkelejda Kasneci

Self-supervised pre-training paradigm has gained increasing prominence for learning transferable representations in medical imaging, yet existing methods for ultrasound (US) images operate at the image or frame level, overlooking the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Chunzheng Zhu , Yijun Wang , Jianxin Lin , Feng Wang , Hongwei Wang , Lei Zhao , Shengli Li , Kenli Li
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