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The role of numerical accuracy in training and evaluating neural network-based potential energy surfaces is examined for different experimental observables. For observables that require third- and fourth-order derivatives of the total…

Chemical Physics · Physics 2023-11-30 Silvan Käser , Markus Meuwly

A new framework is introduced for constructing interpretable and truly reliable reduced models for multiscale problems in situations without scale separation. Hydrodynamic approximation to the kinetic equation is used as an example to…

Computational Physics · Physics 2019-10-31 Jiequn Han , Chao Ma , Zheng Ma , Weinan E

Forecasting the cost evolution of emerging clean technologies is crucial for informed policy, investment, and decarbonization decisions, yet it remains deeply uncertain. Learning curves, which link cost declines to cumulative deployment,…

Systems and Control · Electrical Eng. & Systems 2026-04-21 Mohamed Atouife , Jesse Jenkins

Climate change is causing the intensification of rainfall extremes. Precipitation projections with high spatial resolution are important for society to prepare for these changes, e.g. to model flooding impacts. Physics-based simulations for…

Atmospheric and Oceanic Physics · Physics 2022-11-30 Henry Addison , Elizabeth Kendon , Suman Ravuri , Laurence Aitchison , Peter AG Watson

Material scientists are increasingly adopting the use of machine learning (ML) for making potentially important decisions, such as, discovery, development, optimization, synthesis and characterization of materials. However, despite ML's…

Computational Physics · Physics 2019-03-12 Bhavya Kailkhura , Brian Gallagher , Sookyung Kim , Anna Hiszpanski , T. Yong-Jin Han

Microfluidic devices are increasingly used in biological and chemical experiments due to their cost-effectiveness for rheological estimation in fluids. However, these devices often face challenges in terms of accuracy, size, and cost. This…

Recent advances in power system simulation have included the use of complex rectangular current and voltage (I-V) variables for solving the power flow and three-phase power flow problems. This formulation has demonstrated superior…

Systems and Control · Computer Science 2017-11-07 Amritanshu Pandey , Marko Jereminov , Gabriela Hug , Larry Pileggi

We present the results of Car-Parrinello (CP) simulations of water at ambient conditions and under pressure, using a rigid molecule approximation. Throughout our calculations, water molecules were maintained at a fixed intramolecular…

Condensed Matter · Physics 2009-11-10 M. Allesch , E. Schwegler , F. Gygi , G. Galli

Machine learning potential enables molecular dynamics simulations of systems beyond the capability of classical force fields. The traditional approach to develop structural sets for training machine learning potential typically generate a…

Computational Physics · Physics 2021-09-06 Nan Xu , Chen Li , Mandi Fang , Qing Shao , Yingying Lu , Yao Shi , Yi He

Generating energy functions for heterogeneous systems suitable for quantitative and predictive atomistic simulations is a challenging undertaking. The present work combines a cluster-based approach with electronic structure calculations at…

Chemical Physics · Physics 2025-03-03 Kai Töpfer , Jingchun Wang , Shimoni Patel , Markus Meuwly

Although liquid water is ubiquitous in chemical reactions at roots of life and climate on the earth, the prediction of its properties by high-level ab initio molecular dynamics simulations still represents a formidable task for quantum…

Chemical Physics · Physics 2015-04-22 Andrea Zen , Ye Luo , Guglielmo Mazzola , Leonardo Guidoni , Sandro Sorella

Machine-learned interatomic potentials can offer near first-principles accuracy but are computationally expensive, limiting their application to large-scale molecular dynamics simulations. Inspired by quantum mechanics/molecular mechanics…

Materials Science · Physics 2025-11-21 Fraser Birks , Matthew Nutter , Thomas D Swinburne , James R Kermode

We study the applicability of a Deep Neural Network (DNN) approach to simulate one-dimensional non-relativistic fluid dynamics. Numerical fluid dynamical calculations are used to generate training data-sets corresponding to a broad range of…

Computational Physics · Physics 2021-06-08 Kirill Taradiy , Kai Zhou , Jan Steinheimer , Roman V. Poberezhnyuk , Volodymyr Vovchenko , Horst Stoecker

Accurate simulations of molecules require high-level electronic-structure theory in combination with rigorous methods for approximating the quantum dynamics. Machine-learning approaches can significantly reduce the computational expense of…

Chemical Physics · Physics 2026-02-24 Valerii Andreichev , Jindra Dušek , Markus Meuwly , Jeremy O. Richardson

Quantum mechanics/molecular mechanics (QM/MM) molecular dynamics (MD) simulations have been developed to simulate molecular systems, where an explicit description of changes in the electronic structure is necessary. However, QM/MM MD…

Chemical Physics · Physics 2021-04-15 Lennard Böselt , Moritz Thürlemann , Sereina Riniker

We consider adapting a canonical computer model calibration apparatus, involving coupled Gaussian process (GP) emulators, to a computer experiment simulating radiative shock hydrodynamics that is orders of magnitude larger than what can…

Achieving higher operational voltages, faster charging, and broader temperature ranges for Li-ion batteries necessitates advancements in electrolyte engineering. However, the complexity of optimizing combinations of solvents, salts, and…

Materials Science · Physics 2025-01-10 Suyeon Ju , Jinmu You , Gijin Kim , Yutack Park , Hyungmin An , Seungwu Han

Transition intensities for small molecules such as water and CO$_2$ can now be computed with such high accuracy that they are being used to systematically replace measurements in standard databases. These calculations use high accuracy ab…

Machine learning for molecular property prediction has focused largely on pure compounds, even though many practical applications depend on mixtures with intermolecular interactions. Recent work has expanded the availability of mixture…

Machine Learning · Computer Science 2026-05-29 Roel J. Leenhouts , Nathan K. Morgan , William Green , Jan G. Rittig , Florence H. Vermeire

Crystal nucleation is relevant across the domains of fundamental and applied sciences. However, in many cases its mechanism remains unclear due to a lack of temporal or spatial resolution. To gain insights to the molecular details of…

Soft Condensed Matter · Physics 2024-04-05 Ziyue Zou , Eric Beyerle , Sun-Ting Tsai , Pratyush Tiwary
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