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Semantic segmentation requires dense pixel-level annotations, which are costly and time-consuming to acquire. To address this, we present SeSAM, a framework that uses a foundational segmentation model, i.e. Segment Anything Model (SAM),…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Anurag Das , Anna Kukleva , Xinting Hu , Yuki M. Asano , Bernt Schiele

Recent advancements in biomedical image analysis have been significantly driven by the Segment Anything Model (SAM). This transformative technology, originally developed for general-purpose computer vision, has found rapid application in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Ho Hin Lee , Yu Gu , Theodore Zhao , Yanbo Xu , Jianwei Yang , Naoto Usuyama , Cliff Wong , Mu Wei , Bennett A. Landman , Yuankai Huo , Alberto Santamaria-Pang , Hoifung Poon

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

Accurate segmentation of medical images is fundamental to tumor diagnosis and treatment planning. SAM-based interactive segmentation has gained attention for its strong generalization, but most methods follow a single-point-to-single-object…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Jierui Qu , Jianchun Zhao

End-to-end medical image segmentation is of great value for computer-aided diagnosis dominated by task-specific models, usually suffering from poor generalization. With recent breakthroughs brought by the segment anything model (SAM) for…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Xian Lin , Yangyang Xiang , Li Yu , Zengqiang Yan

Nuclear segmentation in histology images is a challenging task due to significant variations in the shape and appearance of nuclei. One of the main hurdles in nuclear instance segmentation is overlapping nuclei where a smart algorithm is…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Navid Alemi Koohbanani , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

Histopathology plays a pivotal role in medical diagnostics. In contrast to preparing permanent sections for histopathology, a time-consuming process, preparing frozen sections is significantly faster and can be performed during surgery,…

Image and Video Processing · Electrical Eng. & Systems 2023-10-18 Elad Yoshai , Gil Goldinger , Miki Haifler , Natan T. Shaked

It has been shown that traditional deep learning methods for electronic microscopy segmentation usually suffer from low transferability when samples and annotations are limited, while large-scale vision foundation models are more robust…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Yiran Wang , Li Xiao

Segment Anything Model (SAM) has recently achieved amazing results in the field of natural image segmentation. However, it is not effective for medical image segmentation, owing to the large domain gap between natural and medical images. In…

Image and Video Processing · Electrical Eng. & Systems 2024-04-24 Zhengzheng Tu , Le Gu , Xixi Wang , Bo Jiang

Medical image segmentation has been traditionally approached by training or fine-tuning the entire model to cater to any new modality or dataset. However, this approach often requires tuning a large number of parameters during training.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Jay N. Paranjape , Shameema Sikder , S. Swaroop Vedula , Vishal M. Patel

Segment Anything Model (SAM) has attracted significant attention due to its impressive zero-shot transfer performance and high versatility for numerous vision applications (like image editing with fine-grained control). Many of such…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Chaoning Zhang , Dongshen Han , Yu Qiao , Jung Uk Kim , Sung-Ho Bae , Seungkyu Lee , Choong Seon Hong

Segmentation is vital for ophthalmology image analysis. But its various modal images hinder most of the existing segmentation algorithms applications, as they rely on training based on a large number of labels or hold weak generalization…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Zhongxi Qiu , Yan Hu , Heng Li , Jiang Liu

Purpose: Accurate tool segmentation is essential in computer-aided procedures. However, this task conveys challenges due to artifacts' presence and the limited training data in medical scenarios. Methods that generalize to unseen data…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Kanyifeechukwu J. Oguine , Roger D. Soberanis-Mukul , Nathan Drenkow , Mathias Unberath

Tumor segmentation in multimodal medical images has seen a growing trend towards deep learning based methods. Typically, studies dealing with this topic fuse multimodal image data to improve the tumor segmentation contour for a single…

Image and Video Processing · Electrical Eng. & Systems 2020-09-25 Theresa Neubauer , Maria Wimmer , Astrid Berg , David Major , Dimitrios Lenis , Thomas Beyer , Jelena Saponjski , Katja Bühler

In this paper, we propose sparse coding-based approaches for segmentation of tumor regions from MR images. Sparse coding with data-adapted dictionaries has been successfully employed in several image recovery and vision problems. The…

Computer Vision and Pattern Recognition · Computer Science 2013-03-12 Jayaraman J. Thiagarajan , Karthikeyan Natesan Ramamurthy , Deepta Rajan , Anup Puri , David Frakes , Andreas Spanias

The limited availability of labeled data has driven advancements in semi-supervised learning for medical image segmentation. Modern large-scale models tailored for general segmentation, such as the Segment Anything Model (SAM), have…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Kaiwen Huang , Tao Zhou , Huazhu Fu , Yizhe Zhang , Yi Zhou , Chen Gong , Dong Liang

Medical image segmentation assists in computer-aided diagnosis, surgeries, and treatment. Digitize tissue slide images are used to analyze and segment glands, nuclei, and other biomarkers which are further used in computer-aided medical…

Image and Video Processing · Electrical Eng. & Systems 2022-09-05 Saad Wazir , Muhammad Moazam Fraz

The recently proposed Segment Anything Model (SAM) is a general tool for image segmentation, but it requires additional adaptation and careful fine-tuning for medical image segmentation, especially for small, irregularly-shaped, and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Yaxi Chen , Aleksandra Ivanova , Shaheer U. Saeed , Rikin Hargunani , Jie Huang , Chaozong Liu , Yipeng Hu

Multi-modal brain tumor segmentation is critical for clinical diagnosis, and it requires accurate identification of distinct internal anatomical subregions. While the recent prompt-based segmentation paradigms enable interactive experiences…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Yuxiang Luo , Qing Xu , Hai Huang , Yuqi Ouyang , Zhen Chen , Wenting Duan

Prompt-free image segmentation aims to generate accurate masks without manual guidance. Typical pre-trained models, notably Segmentation Anything Model (SAM), generate prompts directly at a single granularity level. However, this approach…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Qiyang Yu , Yu Fang , Tianrui Li , Xuemei Cao , Yan Chen , Jianghao Li , Fan Min , Yi Zhang