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Advances in digital pathology and artificial intelligence (AI) offer promising opportunities for clinical decision support and enhancing diagnostic workflows. Previous studies already demonstrated AI's potential for automated Gleason…
Artificial Intelligence (AI) has great potential to improve health outcomes by training systems on vast digitized clinical datasets. Computational Pathology, with its massive amounts of microscopy image data and impact on diagnostics and…
Digital pathology has revolutionized cancer diagnosis by leveraging Content-Based Medical Image Retrieval (CBMIR) for analyzing histopathological Whole Slide Images (WSIs). CBMIR enables searching for similar content, enhancing diagnostic…
Thyroid cancer is currently the fifth most common malignancy diagnosed in women. Since differentiation of cancer sub-types is important for treatment and current, manual methods are time consuming and subjective, automatic computer-aided…
Basal cell carcinoma (BCC) accounts for about 75% of skin cancers. The adoption of teledermatology protocols in Spanish public hospitals has increased dermatologists' workload, motivating the development of AI tools for lesion…
Automated region of interest detection in histopathological image analysis is a challenging and important topic with tremendous potential impact on clinical practice. The deep-learning methods used in computational pathology may help us to…
Notorious for its 70-80% recurrence rate, Non-muscle-invasive Bladder Cancer (NMIBC) imposes a significant human burden and is one of the costliest cancers to manage. Current tools for predicting NMIBC recurrence rely on scoring systems…
This work shows promising results using multiple instance learning on salivary gland tumours in classifying cancers on whole slide images. Utilising CTransPath as a patch-level feature extractor and CLAM as a feature aggregator, an F1 score…
We propose a method to accurately obtain the ratio of tumor cells over an entire histological slide. We use deep fully convolutional neural network models trained to detect and classify cells on images of H&E-stained tissue sections.…
Despite the growing interest in human-AI decision making, experimental studies with domain experts remain rare, largely due to the complexity of working with domain experts and the challenges in setting up realistic experiments. In this…
Early detection of melanoma, a potentially lethal type of skin cancer with high prevalence worldwide, improves patient prognosis. In retrospective studies, artificial intelligence (AI) has proven to be helpful for enhancing melanoma…
Melanoma diagnosed and treated in its early stages can increase the survival rate. A projected increase in skin cancer incidents and a dearth of dermatopathologists have emphasized the need for computational pathology (CPATH) systems. CPATH…
Colorectal cancer is the third most common tumor in men and the second in women, accounting for 10% of all tumors worldwide. It ranks second in cancer-related deaths with 9.4%, following lung cancer. The decrease in mortality rate…
We hypothesize that anatomical priors can be viable mediums to infuse domain-specific clinical knowledge into state-of-the-art convolutional neural networks (CNN) based on the U-Net architecture. We introduce a probabilistic population…
Thyroid cancer is common worldwide, with a rapid increase in prevalence across North America in recent years. While most patients present with palpable nodules through physical examination, a large number of small and medium-sized nodules…
Advances in optical microscopy scanning have significantly contributed to computational pathology (CPath) by converting traditional histopathological slides into whole slide images (WSIs). This development enables comprehensive digital…
In pathology, whole-slide images (WSI) based survival prediction has attracted increasing interest. However, given the large size of WSIs and the lack of pathologist annotations, extracting the prognostic information from WSIs remains a…
Deciphering tumor microenvironment from Whole Slide Images (WSIs) is intriguing as it is key to cancer diagnosis, prognosis and treatment response. While these gigapixel images on one hand offer a comprehensive portrait of cancer, on the…
Computational analysis of whole slide images (WSIs) has seen significant research progress in recent years, with applications ranging across important diagnostic and prognostic tasks such as survival or cancer subtype prediction. Many…
We present a multi-stage 3D computer-aided detection and diagnosis (CAD) model for automated localization of clinically significant prostate cancer (csPCa) in bi-parametric MR imaging (bpMRI). Deep attention mechanisms drive its detection…