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Deep learning has been effective for histology image analysis in digital pathology. However, many current deep learning approaches require large, strongly- or weakly-labeled images and regions of interest, which can be time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-04-07 Joseph DiPalma , Lorenzo Torresani , Saeed Hassanpour

Medical Vision-language models (VLMs) have shown remarkable performances in various medical imaging domains such as histo\-pathology by leveraging pre-trained, contrastive models that exploit visual and textual information. However,…

Explainability is critical for the clinical adoption of medical visual question answering (VQA) systems, as physicians require transparent reasoning to trust AI-generated diagnoses. We present MedXplain-VQA, a comprehensive framework…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Hai-Dang Nguyen , Minh-Anh Dang , Minh-Tan Le , Minh-Tuan Le

Computational pathology models that use digitized histopathology whole-slide images have the potential to become a cost-effective and scalable alternative to molecular assays for the prediction of genomic biomarkers, a key task in precision…

Quantitative Methods · Quantitative Biology 2026-03-03 Ekaterina Redekop , Eric Zimmermann , Ava P Amini , Alex X Lu , Neil Tenenholtz , James Brian Hall , Lorin Crawford , Kristen A Severson

Automated 3D CT diagnosis empowers clinicians to make timely, evidence-based decisions by enhancing diagnostic accuracy and workflow efficiency. While multimodal large language models (MLLMs) exhibit promising performance in visual-language…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Yanzhao Shi , Xiaodan Zhang , Junzhong Ji , Haoning Jiang , Chengxin Zheng , Yinong Wang , Liangqiong Qu

Visual grounding, which aims to ground a visual region via natural language, is a task that heavily relies on cross-modal alignment. Existing works utilized uni-modal pre-trained models to transfer visual or linguistic knowledge separately…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Linhui Xiao , Xiaoshan Yang , Fang Peng , Yaowei Wang , Changsheng Xu

Electronic health records (EHR) contain narrative notes that provide extensive details on the medical condition and management of patients. Natural language processing (NLP) of clinical notes can use observed frequencies of clinical terms…

Computation and Language · Computer Science 2023-07-04 Bryan Cai , Sihang Zeng , Yucong Lin , Zheng Yuan , Doudou Zhou , Lu Tian

General-purpose Large Vision-Language Models (LVLMs), despite their massive scale, often falter in dermatology due to "diffuse attention" - the inability to disentangle subtle pathological lesions from background noise. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Lijun Liu , Linwei Chen , Zhishou Zhang , Meng Tian , Hengfu Cui , Ruiyang Li , Zhaocheng Liu , Qiang Ju , Qianxi Li , Hong-Yu Zhou

Colorectal diseases, including inflammatory conditions and neoplasms, require quick, accurate care to be effectively treated. Traditional diagnostic pipelines require extensive preparation and rely on separate, individual evaluations on…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Krithik Ramesh , Ritvik Koneru

We present ViDRiP-LLaVA, the first large multimodal model (LMM) in computational pathology that integrates three distinct image scenarios, including single patch images, automatically segmented pathology video clips, and manually segmented…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Trinh T. L. Vuong , Jin Tae Kwak

Deep learning based automated pathological diagnosis has markedly improved diagnostic efficiency and reduced variability between observers, yet its clinical adoption remains limited by opaque model decisions and a lack of traceable…

Pedestrian Attribute Recognition (PAR) involves predicting fine-grained attributes such as clothing color, gender, and accessories from pedestrian imagery, yet is hindered by severe class imbalance, intricate attribute co-dependencies, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Abdellah Zakaria Sellam , Salah Eddine Bekhouche , Fadi Dornaika , Cosimo Distante , Abdenour Hadid

Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ravi Mosalpuri , Mohammed Abdelsamea , Ahmed Karam Eldaly

(Renyi Qu's Master's Thesis) Recent advancements in interpretable models for vision-language tasks have achieved competitive performance; however, their interpretability often suffers due to the reliance on unstructured text outputs from…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Renyi Qu , Mark Yatskar

Clinical variant classification of pathogenic versus benign genetic variants remains a pivotal challenge in clinical genetics. Recently, the proposition of protein language models has improved the generic variant effect prediction (VEP)…

Genomics · Quantitative Biology 2023-11-09 Huixin Zhan , Zijun Zhang

Rare cancers comprise 20-25% of all malignancies but face major diagnostic challenges due to limited expert availability-especially in pediatric oncology, where they represent over 70% of cases. While pathology vision-language (VL)…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Dexuan He , Xiao Zhou , Wenbin Guan , Liyuan Zhang , Xiaoman Zhang , Sinuo Xu , Ge Wang , Lifeng Wang , Xiaojun Yuan , Xin Sun , Yanfeng Wang , Kun Sun , Ya Zhang , Weidi Xie

Vision-language models (VLMs) have the potential to become co-pilots for pathologists. However, most VLMs either focus on small regions of interest within whole-slide images, provide only static slide-level outputs, or rely on data that is…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Sander Moonemans , Sebastiaan Ram , Frédérique Meeuwsen , Carlijn Lems , Jeroen van der Laak , Geert Litjens , Francesco Ciompi

Pathological diagnosis is vital for determining disease characteristics, guiding treatment, and assessing prognosis, relying heavily on detailed, multi-scale analysis of high-resolution whole slide images (WSI). However, existing large…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Shengxuming Zhang , Weihan Li , Tianhong Gao , Jiacong Hu , Haoming Luo , Xiuming Zhang , Jing Zhang , Mingli Song , Zunlei Feng

Hierarchical attention networks have recently achieved remarkable performance for document classification in a given language. However, when multilingual document collections are considered, training such models separately for each language…

Computation and Language · Computer Science 2017-09-18 Nikolaos Pappas , Andrei Popescu-Belis

Representation learning from Gigapixel Whole Slide Images (WSI) poses a significant challenge in computational pathology due to the complicated nature of tissue structures and the scarcity of labeled data. Multi-instance learning methods…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Ali Nasiri-Sarvi , Vincent Quoc-Huy Trinh , Hassan Rivaz , Mahdi S. Hosseini
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