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The advancement of general medical Multimodal Large Language Models (MLLMs) has shown great potential for building conversational assistants to support clinical diagnosis. However, their adaptation to highly specialized domains such as…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Xuanzhao Dong , Wenhui Zhu , Xiwen Chen , Hao Wang , Xin Li , Yujian Xiong , Jiajun Cheng , Jingjing Wang , Xiaobing Yu , Haiyu Wu , Shao Tang , Zhipeng Wang , Langechuan Liu , Shan Lin , Oana Dumitrascu , Yalin Wang

Large language models (LLMs) have recently shown strong progress on scientific reasoning, yet two major bottlenecks remain. First, explicit retrieval fragments reasoning, imposing a hidden "tool tax" of extra tokens and steps. Second,…

In this paper, we introduce S-MedQA, an English medical question-answering (QA) dataset designed for benchmarking large language models (LLMs) in fine-grained clinical specialties. S-MedQA consists of over 24k examples, covering 15 medical…

Computation and Language · Computer Science 2026-01-28 Xinlan Yan , Di Wu , Yibin Lei , Christof Monz , Iacer Calixto

Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

Qualitative data analysis (QDA) emphasizes trustworthiness, requiring sustained human engagement and reflexivity. Recently, large language models (LLMs) have been applied in QDA to improve efficiency. However, their use raises concerns…

Human-Computer Interaction · Computer Science 2025-10-28 Jie Gao , Zhiyao Shu , Shun Yi Yeo , Alok Prakash , Chien-Ming Huang , Mark Dredze , Ziang Xiao

Recent artificial intelligence (AI) systems have reached milestones in "grand challenges" ranging from Go to protein-folding. The capability to retrieve medical knowledge, reason over it, and answer medical questions comparably to…

Medical question-answering (QA) systems can benefit from advances in large language models (LLMs), but directly applying LLMs to the clinical domain poses challenges such as maintaining factual accuracy and avoiding hallucinations. In this…

Computation and Language · Computer Science 2025-12-08 Tasnimul Hassan , Md Faisal Karim , Haziq Jeelani , Elham Behnam , Robert Green , Fayeq Jeelani Syed

Patient experience and care quality are crucial for a hospital's sustainability and reputation. The analysis of patient feedback offers valuable insight into patient satisfaction and outcomes. However, the unstructured nature of these…

Computation and Language · Computer Science 2025-02-21 Hajar Sakai , Sarah S. Lam , Mohammadsadegh Mikaeili , Joshua Bosire , Franziska Jovin

Quickly resolving issues reported in industrial applications is crucial to minimize economic impact. However, the required data analysis makes diagnosing the underlying root causes a challenging and time-consuming task, even for experts. In…

Computation and Language · Computer Science 2024-10-15 Jordis Emilia Herrmann , Aswath Mandakath Gopinath , Mikael Norrlof , Mark Niklas Müller

As large language models (LLMs) become increasingly integrated into clinical decision-making, ensuring transparent and trustworthy reasoning is essential. However, existing evaluation strategies of LLMs' medical reasoning capability either…

Large language models (LLMs) have demonstrated promising performance on medical benchmarks; however, their ability to perform medical calculations, a crucial aspect of clinical decision-making, remains underexplored and poorly evaluated.…

Computation and Language · Computer Science 2026-02-03 Benlu Wang , Iris Xia , Yifan Zhang , Junda Wang , Feiyun Ouyang , Shuo Han , Arman Cohan , Hong Yu , Zonghai Yao

In this study, we present MedS-Bench, a comprehensive benchmark designed to evaluate the performance of large language models (LLMs) in clinical contexts. Unlike existing benchmarks that focus on multiple-choice question answering,…

Computation and Language · Computer Science 2024-09-06 Chaoyi Wu , Pengcheng Qiu , Jinxin Liu , Hongfei Gu , Na Li , Ya Zhang , Yanfeng Wang , Weidi Xie

LLMs have demonstrated impressive performance in answering medical questions, such as achieving passing scores on medical licensing examinations. However, medical board exams or general clinical questions do not capture the complexity of…

Computation and Language · Computer Science 2026-02-19 Hanjie Chen , Zhouxiang Fang , Yash Singla , Mark Dredze

A question-answering (QA) system is to search suitable answers within a knowledge base. Current QA systems struggle with queries requiring complex reasoning or real-time knowledge integration. They are often supplemented with retrieval…

Computation and Language · Computer Science 2025-05-21 Sizhe Yuen , Ting Su , Ziyang Wang , Yali Du , Adam J. Sobey

Image Quality Assessment (IQA) is a critical task in a wide range of applications but remains challenging due to the subjective nature of human perception and the complexity of real-world image distortions. This study proposes MetaQAP, a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-17 Nisar Ahmed , Gulshan Saleem , Nazik Alturki , Nada Alasbali

Recent advancements in Multi-modality Large Language Models (MLLMs) have demonstrated remarkable capabilities in complex high-level vision tasks. However, the exploration of MLLM potential in visual quality assessment, a vital aspect of…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Zicheng Zhang , Haoning Wu , Zhongpeng Ji , Chunyi Li , Erli Zhang , Wei Sun , Xiaohong Liu , Xiongkuo Min , Fengyu Sun , Shangling Jui , Weisi Lin , Guangtao Zhai

Recent advances in Multimodal Large Language Models (MLLMs) have demonstrated impressive capabilities. However, evaluating their capacity for human-like understanding in One-Image Guides remains insufficiently explored. One-Image Guides are…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Jiancong Xie , Wenjin Wang , Zhuomeng Zhang , Zihan Liu , Qi Liu , Ke Feng , Zixun Sun , Yuedong Yang

Large language models (LLMs) are rapidly transitioning into medical clinical use, yet their reliability under realistic, multi-turn interactions remains poorly understood. Existing evaluation frameworks typically assess single-turn question…

Computation and Language · Computer Science 2025-10-15 Blazej Manczak , Eric Lin , Francisco Eiras , James O' Neill , Vaikkunth Mugunthan

This study focuses on the evaluation of the Open Question Answering (Open-QA) task, which can directly estimate the factuality of large language models (LLMs). Current automatic evaluation methods have shown limitations, indicating that…

Computation and Language · Computer Science 2023-10-24 Cunxiang Wang , Sirui Cheng , Qipeng Guo , Yuanhao Yue , Bowen Ding , Zhikun Xu , Yidong Wang , Xiangkun Hu , Zheng Zhang , Yue Zhang

Reading and understanding text is one important component in computer aided diagnosis in clinical medicine, also being a major research problem in the field of NLP. In this work, we introduce a question-answering task called MedQA to study…

Computation and Language · Computer Science 2018-03-01 Xiao Zhang , Ji Wu , Zhiyang He , Xien Liu , Ying Su