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Medical Image Quality Assessment (IQA) serves as the first-mile safety gate for clinical AI, yet existing approaches remain constrained by scalar, score-based metrics and fail to reflect the descriptive, human-like reasoning process central…

Large language models perform well on many medical QA benchmarks, but real clinical reasoning often requires integrating evidence across multiple images rather than interpreting a single view. We introduce MedThinkVQA, an expert-annotated…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Zonghai Yao , Benlu Wang , Yifan Zhang , Junda Wang , Iris Xia , Zhipeng Tang , Shuo Han , Feiyun Ouyang , Zhichao Yang , Arman Cohan , Hong Yu

Rapid advances in medical imaging technology underscore the critical need for precise and automated image quality assessment (IQA) to ensure diagnostic accuracy. Existing medical IQA methods, however, struggle to generalize across diverse…

Computer Vision and Pattern Recognition · Computer Science 2025-07-28 Siyi Xun , Yue Sun , Jingkun Chen , Zitong Yu , Tong Tong , Xiaohong Liu , Mingxiang Wu , Tao Tan

Despite the great advance of Multimodal Large Language Models (MLLMs) in both instruction dataset building and benchmarking, the independence of training and evaluation makes current MLLMs hard to further improve their capability under the…

Machine Learning · Computer Science 2023-09-12 Zhiyuan Zhao , Linke Ouyang , Bin Wang , Siyuan Huang , Pan Zhang , Xiaoyi Dong , Jiaqi Wang , Conghui He

The rapid progress of multi-modal large language models (MLLMs) has boosted the task of image quality assessment (IQA). However, a key challenge arises from the inherent mismatch between the discrete token outputs of MLLMs and the…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Zhenchen Tang , Songlin Yang , Bo Peng , Zichuan Wang , Jing Dong

Image Quality Assessment (IQA) models are increasingly deployed as perceptual critics to guide generative models and image restoration. This role demands not only accurate scores but also actionable, localized feedback. However, current…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Xudong Li , Jiaxi Tan , Ziyin Zhou , Yan Zhong , Zihao Huang , Jingyuan Zheng , Yan Zhang , Xiawu Zheng , Rongrong Ji

Existing medical image restoration (Med-IR) methods are typically modality-specific or degradation-specific, failing to generalize across the heterogeneous degradations encountered in clinical practice. We argue this limitation stems from…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Jiyao Liu , Junzhi Ning , Wanying Qu , Lihao Liu , Chenglong Ma , Junjun He , Ningsheng Xu

Despite impressive performance on standard benchmarks, multimodal large language models (MLLMs) face critical challenges in real-world clinical environments where medical images inevitably suffer various quality degradations. Existing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Jiyao Liu , Junzhi Ning , Chenglong Ma , Wanying Qu , Jianghan Shen , Siqi Luo , Jinjie Wei , Jin Ye , Pengze Li , Tianbin Li , Jiashi Lin , Hongming Shan , Xinzhe Luo , Xiaohong Liu , Lihao Liu , Junjun He , Ningsheng Xu

Evaluating natural language generation (NLG) systems in the medical domain presents unique challenges due to the critical demands for accuracy, relevance, and domain-specific expertise. Traditional automatic evaluation metrics, such as…

Computation and Language · Computer Science 2025-09-17 Wen-wai Yim , Asma Ben Abacha , Zixuan Yu , Robert Doerning , Fei Xia , Meliha Yetisgen

The rapid advancement of Multi-modal Large Language Models (MLLMs) has expanded their capabilities beyond high-level vision tasks. Nevertheless, their potential for Document Image Quality Assessment (DIQA) remains underexplored. To bridge…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Jiaxi Huang , Dongxu Wu , Hanwei Zhu , Lingyu Zhu , Jun Xing , Xu Wang , Baoliang Chen

Image Quality Assessment (IQA) is important for scientific inquiry, especially in medical imaging and machine learning. Potential data quality issues can be exacerbated when human-based workflows use limited views of the data that may…

Computer Vision and Pattern Recognition · Computer Science 2021-07-28 Riqiang Gao , Mirza S. Khan , Yucheng Tang , Kaiwen Xu , Steve Deppen , Yuankai Huo , Kim L. Sandler , Pierre P. Massion , Bennett A. Landman

In recent years, with the rapid development of powerful multimodal large language models (MLLMs), explainable image quality assessment (IQA) has gradually become popular, aiming at providing quality-related descriptions and answers of…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Yunhao Li , Sijing Wu , Huiyu Duan , Yucheng Zhu , Qi Jia , Guangtao Zhai

Image Quality Assessment (IQA) remains an unresolved challenge in computer vision due to complex distortions, diverse image content, and limited data availability. Existing Blind IQA (BIQA) methods largely rely on extensive human…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Xudong Li , Zihao Huang , Yan Zhang , Yunhang Shen , Ke Li , Xiawu Zheng , Liujuan Cao , Rongrong Ji

Real-world clinical practice demands multi-image comparative reasoning, yet current medical benchmarks remain limited to single-frame interpretation. We present MedFrameQA, the first benchmark explicitly designed to test multi-image medical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Suhao Yu , Haojin Wang , Juncheng Wu , Luyang Luo , Jingshen Wang , Cihang Xie , Pranav Rajpurkar , Carl Yang , Yang Yang , Kang Wang , Yannan Yu , Yuyin Zhou

With the dramatic upsurge in the volume of ultrasound examinations, low-quality ultrasound imaging has gradually increased due to variations in operator proficiency and imaging circumstances, imposing a severe burden on diagnosis accuracy…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Hongyi Miao , Jun Jia , Yankun Cao , Yingjie Zhou , Yanwei Jiang , Zhi Liu , Guangtao Zhai

Image quality assessment (IQA) plays a critical role in optimizing radiation dose and developing novel medical imaging techniques in computed tomography (CT). Traditional IQA methods relying on hand-crafted features have limitations in…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Tao Song , Ruizhi Hou , Lisong Dai , Lei Xiang

This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

Computation and Language · Computer Science 2024-07-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Honghan Wu

Image Quality Assessment (IQA) has progressed from scalar quality prediction to more interpretable, human-aligned evaluation paradigms. In this work, we address the emerging challenge of detailed and explainable IQA by proposing iDETEX-a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Zhaoran Zhao , Xinli Yue , Jianhui Sun , Yuhao Xie , Tao Shao , Liangchao Yao , Fan Xia , Yuetang Deng

Multimodal Large Language Models are increasingly applied to biomedical imaging, yet scientific reasoning for microscopy remains limited by the scarcity of large-scale, high-quality training data. We introduce MicroVQA++, a three-stage,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Manyu Li , Ruian He , Chenxi Ma , Weimin Tan , Bo Yan

The accelerating development of general medical artificial intelligence (GMAI), powered by multimodal large language models (MLLMs), offers transformative potential for addressing persistent healthcare challenges, including workforce…

Artificial Intelligence · Computer Science 2025-06-03 Sau Lai Yip , Sunan He , Yuxiang Nie , Shu Pui Chan , Yilin Ye , Sum Ying Lam , Hao Chen
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