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Identification of drug-target interactions is an indispensable part of drug discovery. While conventional shallow machine learning and recent deep learning methods based on chemogenomic properties of drugs and target proteins have pushed…

Quantitative Methods · Quantitative Biology 2024-04-05 Yuanyuan Zhang , Yingdong Wang , Chaoyong Wu , Lingmin Zhana , Aoyi Wang , Caiping Cheng , Jinzhong Zhao , Wuxia Zhang , Jianxin Chen , Peng Li

Medical image segmentation requires models that preserve fine anatomical boundaries while remaining practical for clinical deployment. Transformers capture long-range dependencies but incur quadratic attention cost, whereas CNNs are…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Hongbo Zheng , Afshin Bozorgpour , Dorit Merhof , Minjia Zhang

Accurate 3D reconstruction of deformable soft tissues is essential for surgical robotic perception. However, low-texture surfaces, specular highlights, and instrument occlusions often fragment geometric continuity, posing a challenge for…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Falong Fan , Yi Xie , Arnis Lektauers , Bo Liu , Jerzy Rozenblit

We present Bi-Level Attention-Based Relational Graph Convolutional Networks (BR-GCN), unique neural network architectures that utilize masked self-attentional layers with relational graph convolutions, to effectively operate on highly…

Machine Learning · Computer Science 2024-04-16 Roshni G. Iyer , Wei Wang , Yizhou Sun

We propose the Gaussian Gated Linear Network (G-GLN), an extension to the recently proposed GLN family of deep neural networks. Instead of using backpropagation to learn features, GLNs have a distributed and local credit assignment…

Machine Learning · Computer Science 2020-10-22 David Budden , Adam Marblestone , Eren Sezener , Tor Lattimore , Greg Wayne , Joel Veness

Graph convolutional networks (GCNs), which can model the human body skeletons as spatial and temporal graphs, have shown remarkable potential in skeleton-based action recognition. However, in the existing GCN-based methods, graph-structured…

Computer Vision and Pattern Recognition · Computer Science 2022-10-13 Han Chen , Yifan Jiang , Hanseok Ko

Functional alterations in the relevant neural circuits occur from drug addiction over a certain period. And these significant alterations are also revealed by analyzing fMRI. However, because of fMRI's high dimensionality and poor…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Changwei Gong , Changhong Jing , Junren Pan , Shuqiang Wang

The state-of-the-art approaches in Generative Adversarial Networks (GANs) are able to learn a mapping function from one image domain to another with unpaired image data. However, these methods often produce artifacts and can only be able to…

Computer Vision and Pattern Recognition · Computer Science 2019-08-29 Hao Tang , Dan Xu , Nicu Sebe , Yan Yan

Person re-identification (reID) aims at retrieving a person from images captured by different cameras. For deep-learning-based reID methods, it has been proved that using local features together with global feature could help to give robust…

Computer Vision and Pattern Recognition · Computer Science 2022-01-11 Zhijun He , Hongbo Zhao , Wenquan Feng

Fine-grained object classification is a challenging task due to the subtle inter-class difference and large intra-class variation. Recently, visual attention models have been applied to automatically localize the discriminative regions of…

Computer Vision and Pattern Recognition · Computer Science 2018-02-27 Bo Zhao , Xiao Wu , Jiashi Feng , Qiang Peng , Shuicheng Yan

In multi-robot collaborative area search, a key challenge is to dynamically balance the two objectives of exploring unknown areas and covering specific targets to be rescued. Existing methods are often constrained by homogeneous graph…

Robotics · Computer Science 2026-01-08 Lina Zhu , Jiyu Cheng , Yuehu Liu , Wei Zhang

Deep learning-based pavement cracks detection methods often require large-scale labels with detailed crack location information to learn accurate predictions. In practice, however, crack locations are very difficult to be manually annotated…

Computer Vision and Pattern Recognition · Computer Science 2023-02-14 Huijun Liu , Chunhua Yang , Ao Li , Sheng Huang , Xin Feng , Zhimin Ruan , Yongxin Ge

Predicting accurate protein-ligand binding affinity is important in drug discovery but remains a challenge even with computationally expensive biophysics-based energy scoring methods and state-of-the-art deep learning approaches. Despite…

Traffic forecasting is one canonical example of spatial-temporal learning task in Intelligent Traffic System. Existing approaches capture spatial dependency with a pre-determined matrix in graph convolution neural operators. However, the…

Machine Learning · Computer Science 2022-06-08 Chen Weikang , Li Yawen , Xue Zhe , Li Ang , Wu Guobin

Graph-based learning is a rapidly growing sub-field of machine learning with applications in social networks, citation networks, and bioinformatics. One of the most popular models is graph attention networks. They were introduced to allow a…

Machine Learning · Computer Science 2023-05-23 Kimon Fountoulakis , Amit Levi , Shenghao Yang , Aseem Baranwal , Aukosh Jagannath

Signed link prediction in graphs is an important problem that has applications in diverse domains. It is a binary classification problem that predicts whether an edge between a pair of nodes is positive or negative. Existing approaches for…

Social and Information Networks · Computer Science 2022-01-19 Roshni Chakraborty , Ritwika Das , Joydeep Chandra

Graph neural networks (GNNs) are widely used as surrogates for costly experiments and first-principles simulations to study the behavior of compounds at atomistic scale, and their architectural complexity is constantly increasing to enable…

Machine Learning · Computer Science 2026-05-04 Arindam Chowdhury , Massimiliano Lupo Pasini

With the explosion of graph-structured data, link prediction has emerged as an increasingly important task. Embedding methods for link prediction utilize neural networks to generate node embeddings, which are subsequently employed to…

Machine Learning · Computer Science 2023-06-21 Jun Fu , Xiaojuan Zhang , Shuang Li , Dali Chen

Graph neural networks (GNNs) have shown great ability for node classification on graphs. However, the success of GNNs relies on abundant labeled data, while obtaining high-quality labels is costly and challenging, especially for newly…

Machine Learning · Computer Science 2025-06-02 Yilong Wang , Tianxiang Zhao , Zongyu Wu , Suhang Wang

Graph data often exhibits complex geometric heterogeneity, where structures with varying local curvature, such as tree-like hierarchies and dense communities, coexist within a single network. Existing geometric GNNs, which embed graphs into…

Machine Learning · Computer Science 2026-01-21 Xudong Wang , Chris Ding , Tongxin Li , Jicong Fan
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