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Real-world optimization problems are generally not just black-box problems, but also involve mixed types of inputs in which discrete and continuous variables coexist. Such mixed-space optimization possesses the primary challenge of modeling…

Machine Learning · Computer Science 2022-02-09 Jaeyeon Ahn , Taehyeon Kim , Seyoung Yun

Encoding models are used for predicting brain activity in response to sensory stimuli with the objective of elucidating how sensory information is represented in the brain. Encoding models typically comprise a nonlinear transformation of…

Neurons and Cognition · Quantitative Biology 2017-03-13 Umut Güçlü , Marcel A. J. van Gerven

Assigning passenger trips to specific network paths using automatic fare collection (AFC) data is a fundamental application in urban transit analysis. The task is a difficult inverse problem: the only available information consists of each…

Applications · Statistics 2025-07-31 Xiaoxu Chen , Alexandra M. Schmidt , Zhenliang Ma , Lijun Sun

Staged trees are a relatively recent class of probabilistic graphical models that extend Bayesian networks to formally and graphically account for non-symmetric patterns of dependence. Machine learning algorithms to learn them from data…

Applications · Statistics 2024-01-04 Manuele Leonelli , Gherardo Varando

This paper presents a multiscale approach to efficiently compute approximate optimal transport plans between point sets. It is particularly well-suited for point sets that are in high-dimensions, but are close to being intrinsically…

Machine Learning · Computer Science 2021-04-13 Samuel Gerber , Mauro Maggioni

We present a bipartite network model that captures intermediate stages of optimization by blending the Maximum Entropy approach with Optimal Transport. In this framework, the network's constraints define the total mass each node can supply…

Statistical Mechanics · Physics 2026-02-05 Lorenzo Buffa , Dario Mazzilli , Riccardo Piombo , Fabio Saracco , Giulio Cimini , Aurelio Patelli

Cerebral autoregulation plays a key physiological role by limiting blood flow changes in the face of pressure fluctuations. Although the involved cellular processes are mechanically driven, the quantification of haemodynamic forces in…

Quantitative Methods · Quantitative Biology 2024-11-15 Alberto Coccarelli , Ioannis Polydoros , Alex Drysdale , Osama F. Harraz , Chennakesava Kadapa

Transport-based techniques for signal and data analysis have received increased attention recently. Given their abilities to provide accurate generative models for signal intensities and other data distributions, they have been used in a…

Computer Vision and Pattern Recognition · Computer Science 2016-09-23 Soheil Kolouri , Serim Park , Matthew Thorpe , Dejan Slepčev , Gustavo K. Rohde

Estimating brain microstructure has important applications in medicine and neuroscience. Diffusion-weighted magnetic resonance imaging enables measuring microstructure \textit{in vivo}. Conventional biophysical model fitting can be accurate…

Medical Physics · Physics 2026-03-09 Leevi Kerkelä , Hui Zhang

Adaptive multilevel splitting algorithms have been introduced rather recently for estimating tail distributions in a fast and efficient way. In particular, they can be used for computing the so-called reactive trajectories corresponding to…

Numerical Analysis · Mathematics 2014-12-25 Joran Rolland , Eric Simonnet

Decoding language from the human brain remains a grand challenge for Brain-Computer Interfaces (BCIs). Current approaches typically rely on unimodal brain representations, neglecting the brain's inherently multimodal processing. Inspired by…

Computation and Language · Computer Science 2025-08-12 Chunyu Ye , Yunhao Zhang , Jingyuan Sun , Chong Li , Chengqing Zong , Shaonan Wang

Taking inspiration from how the brain coordinates multiple learning systems is an appealing strategy to endow robots with more flexibility. One of the expected advantages would be for robots to autonomously switch to the least costly system…

Robotics · Computer Science 2020-07-17 Rémi Dromnelle , Erwan Renaudo , Guillaume Pourcel , Raja Chatila , Benoît Girard , Mehdi Khamassi

Automated driving in urban scenarios requires efficient planning algorithms able to handle complex situations in real-time. A popular approach is to use graph-based planning methods in order to obtain a rough trajectory which is…

Robotics · Computer Science 2021-02-17 Oliver Speidel , Jona Ruof , Klaus Dietmayer

Efficient path planning and navigation is critical for animals, robotics, logistics and transportation. We study a model in which spatial navigation problems can rapidly be solved in the brain by parallel mental exploration of alternative…

Neurons and Cognition · Quantitative Biology 2012-05-03 Filip Ponulak , John J. Hopfield

In the study of neurons, morphology influences function. The complexity in the structure of neurons poses a challenge in the identification and analysis of similar and dissimilar neuronal cells. Existing methodologies carry out structural…

Image and Video Processing · Electrical Eng. & Systems 2018-02-21 Tamal Batabyal , Scott T. Acton

Efficient spatial navigation is a hallmark of the mammalian brain, inspiring the development of neuromorphic systems that mimic biological principles. Despite progress, implementing key operations like back-tracing and handling ambiguity in…

Neural and Evolutionary Computing · Computer Science 2025-03-31 Robin Dietrich , Tobias Fischer , Nicolai Waniek , Nico Reeb , Michael Milford , Alois Knoll , Adam D. Hines

In this paper, we aim to forecast a future trajectory distribution of a moving agent in the real world, given the social scene images and historical trajectories. Yet, it is a challenging task because the ground-truth distribution is…

Computer Vision and Pattern Recognition · Computer Science 2022-04-01 Ke Guo , Wenxi Liu , Jia Pan

We present a two-scale topology optimization framework for the design of macroscopic bodies with an optimized elastic response, which is achieved by means of a spatially-variant cellular architecture on the microscale. The chosen spinodoid…

Computational Engineering, Finance, and Science · Computer Science 2021-05-21 Li Zheng , Siddhant Kumar , Dennis M. Kochmann

Neurons exhibit intricate geometries within their neurite networks, which play a crucial role in processes such as signaling and nutrient transport. Accurate simulation of material transport in the networks is essential for understanding…

Machine Learning · Computer Science 2025-07-16 Tsung Yeh Hsieh , Yongjie Jessica Zhang

Learning depends on changes in synaptic connections deep inside the brain. In multilayer networks, these changes are triggered by error signals fed back from the output, generally through a stepwise inversion of the feedforward processing…

Neurons and Cognition · Quantitative Biology 2021-01-05 William F. Podlaski , Christian K. Machens