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The simulation of blood flow and pressure in arteries requires outflow boundary conditions that incorporate models of downstream domains. We previously described a coupled multidomain method to couple analytical models of the downstream…

Medical Physics · Physics 2020-07-17 Irene Vignon-Clementel , C. A. Figueroa , K. E. Jansen , C. A. Taylor

3D-0D coupled flow models are widely used across many application fields but remain challenging to solve. Implicit coupling introduces non-local terms, whereas explicit coupling results in only conditionally stable schemes. Furthermore,…

Numerical Analysis · Mathematics 2025-12-10 Jeremías Garay , David Nolte , Cristóbal Bertoglio

Flow matching (FM) learns vector fields by regressing stochastic velocity targets along intermediate distributions $p_t$. We identify a geometric optimization bottleneck in this regression problem: when the covariance $\Sigma_t$ of $p_t$ is…

Machine Learning · Computer Science 2026-05-14 Shadab Ahamed , Eshed Gal , Md Shahriar Rahim Siddiqui , Simon Ghyselincks , Moshe Eliasof , Eldad Haber

Understanding time-dependent blood flow dynamics in arteries is crucial for diagnosing and treating cardiovascular diseases. However, accurately predicting time-varying flow patterns requires integrating observational data with…

Fluid Dynamics · Physics 2025-01-09 Muhammad Adnan Anwar , Jorge Tiago

This paper presents a spatially and temporally adaptive boundary condition to specify the volumetric flux for lattice Boltzmann methods. The approach differs from standard velocity boundary conditions because it allows the velocity to vary…

Computational Physics · Physics 2018-06-28 James E. McClure , Zhe Li , Adrian P. Sheppard , Cass T. Miller

The choice of appropriate boundary conditions is a fundamental step in computational fluid dynamics (CFD) simulations of the cardiovascular system. Boundary conditions, in fact, highly affect the computed pressure and flow rates, and…

This study presents a conditional flow matching framework for solving physics-constrained Bayesian inverse problems. In this setting, samples from the joint distribution of inferred variables and measurements are assumed available, while…

Given an inverse problem with a normalizing flow prior, we wish to estimate the distribution of the underlying signal conditioned on the observations. We approach this problem as a task of conditional inference on the pre-trained…

Machine Learning · Statistics 2021-06-16 Jay Whang , Erik M. Lindgren , Alexandros G. Dimakis

Foundation models have demonstrated remarkable performance across modalities such as language and vision. However, model reuse across distinct modalities (e.g., text and vision) remains limited due to the difficulty of aligning internal…

Machine Learning · Computer Science 2025-05-20 Ali Gholamzadeh , Noor Sajid

Bayesian inference provides a natural way of incorporating prior beliefs and assigning a probability measure to the space of hypotheses. Current solutions rely on iterative routines like Markov Chain Monte Carlo (MCMC) sampling and…

Machine Learning · Computer Science 2025-02-11 Sarthak Mittal , Niels Leif Bracher , Guillaume Lajoie , Priyank Jaini , Marcus Brubaker

Autonomous driving requires reasoning about interactions with surrounding traffic. A prevailing approach is large-scale imitation learning on expert driving datasets, aimed at generalizing across diverse real-world scenarios. For online…

We present a novel technique for amortized posterior estimation using Normalizing Flows trained with likelihood-weighted importance sampling. This approach allows for the efficient inference of theoretical parameters in high-dimensional…

Machine Learning · Computer Science 2026-02-23 Rajneil Baruah

Inferring trajectories from longitudinal spatially-resolved omics data is fundamental to understanding the dynamics of structural and functional tissue changes in development, regeneration and repair, disease progression, and response to…

Machine Learning · Computer Science 2026-05-15 Santanu Subhash Rathod , Francesco Ceccarelli , Sean B. Holden , Pietro Liò , Xiao Zhang , Jovan Tanevski

It is well known that in the computational fluid dynamics simulations related to the cardiovascular system the enforcement of outflow boundary conditions is a crucial point. In fact, they highly affect the computed flow and a wrong setup…

Fluid Dynamics · Physics 2025-03-05 Zahra Mirzaiyan , Michele Girfoglio , Gianluigi Rozza

We introduce a graceful approach to probabilistic inference called bounded conditioning. Bounded conditioning monotonically refines the bounds on posterior probabilities in a belief network with computation, and converges on final…

Artificial Intelligence · Computer Science 2013-04-08 Eric J. Horvitz , Jaap Suermondt , Gregory F. Cooper

Purpose- Coarctation of the Aorta (CoA) patient-specific computational fluid dynamics (CFD) studies in resource constrained settings are limited by the available imaging modalities for geometry and velocity data acquisition. Doppler…

Computational Engineering, Finance, and Science · Computer Science 2025-06-04 Vincent Milimo Masilokwa Punabantu , Malebogo Ngoepe , Amit Kumar Mishra , Thomas Aldersley , John Lawrenson , Liesl Zuhlke

We propose a novel amortized variational inference scheme for an empirical Bayes meta-learning model, where model parameters are treated as latent variables. We learn the prior distribution over model parameters conditioned on limited…

Machine Learning · Computer Science 2020-08-31 Ekaterina Iakovleva , Jakob Verbeek , Karteek Alahari

Conditional generative modeling aims to learn a conditional data distribution from samples containing data-condition pairs. For this, diffusion and flow-based methods have attained compelling results. These methods use a learned (flow)…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Chen Chen , Pengsheng Guo , Liangchen Song , Jiasen Lu , Rui Qian , Xinze Wang , Tsu-Jui Fu , Wei Liu , Yinfei Yang , Alex Schwing

Analyzing complex fluid flow problems that involve multiple coupled domains, each with their respective set of governing equations, is not a trivial undertaking. Even more complicated is the elaborate and tedious task of specifying the…

Fluid Dynamics · Physics 2017-08-18 Alexandre Martin , Huaibao Zhang , Kaveh A. Tagavi

The choice of appropriate boundary conditions is a crucial step in the development of cardiovascular models for blood flow simulations. The three-element Windkessel model is usually employed as a lumped boundary condition, providing a…

Medical Physics · Physics 2022-08-25 Elisa Fevola , Tommaso Bradde , Piero Triverio , Stefano Grivet-Talocia
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