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Current medical retrieval benchmarks primarily emphasize lexical or shallow semantic similarity, overlooking the reasoning-intensive demands that are central to clinical decision-making. In practice, physicians often retrieve authoritative…

Information Retrieval · Computer Science 2026-04-07 Xiangxu Zhang , Lei Li , Xiao Zhou , Zheng Liu

Multimodal retrieval is becoming a crucial component of modern AI applications, yet its evaluation lags behind the demands of more realistic and challenging scenarios. Existing benchmarks primarily probe surface-level semantic…

Information Retrieval · Computer Science 2025-10-01 Junjie Zhou , Ze Liu , Lei Xiong , Jin-Ge Yao , Yueze Wang , Shitao Xiao , Fenfen Lin , Miguel Hu Chen , Zhicheng Dou , Siqi Bao , Defu Lian , Yongping Xiong , Zheng Liu

Logical reasoning is a fundamental aspect of human intelligence and an essential capability for multimodal large language models (MLLMs). Despite the significant advancement in multimodal reasoning, existing benchmarks fail to…

Artificial Intelligence · Computer Science 2025-05-28 Jiakang Yuan , Tianshuo Peng , Yilei Jiang , Yiting Lu , Renrui Zhang , Kaituo Feng , Chaoyou Fu , Tao Chen , Lei Bai , Bo Zhang , Xiangyu Yue

The rapid evolution of Multimodal Large Language Models (MLLMs) has brought substantial advancements in artificial intelligence, significantly enhancing the capability to understand and generate multimodal content. While prior studies have…

Artificial Intelligence · Computer Science 2024-09-30 Lin Li , Guikun Chen , Hanrong Shi , Jun Xiao , Long Chen

Large language models (LLMs) have demonstrated significant potential in clinical decision support. Yet LLMs still suffer from hallucinations and lack fine-grained contextual medical knowledge, limiting their high-stake healthcare…

Computation and Language · Computer Science 2025-04-22 Pengcheng Jiang , Cao Xiao , Minhao Jiang , Parminder Bhatia , Taha Kass-Hout , Jimeng Sun , Jiawei Han

The ability to process information from multiple modalities and to reason through it step-by-step remains a critical challenge in advancing artificial intelligence. However, existing reasoning benchmarks focus on text-only reasoning, or…

Artificial Intelligence · Computer Science 2025-07-01 Yulun Jiang , Yekun Chai , Maria Brbić , Michael Moor

Existing benchmarks for evaluating the clinical reasoning capabilities of large language models (LLMs) often lack a clear definition of "clinical reasoning" as a construct, fail to capture the full breadth of interdependent tasks within a…

Clinical diagnosis prediction models, when provided with a patient's medical history, aim to detect potential diseases early, facilitating timely intervention and improving prognostic outcomes. However, the inherent scarcity of patient data…

Computation and Language · Computer Science 2025-01-30 Mingyu Derek Ma , Xiaoxuan Wang , Yijia Xiao , Anthony Cuturrufo , Vijay S Nori , Eran Halperin , Wei Wang

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Large language models (LLMs) have shown remarkable ability in various language tasks, especially with their emergent in-context learning capability. Extending LLMs to incorporate visual inputs, large vision-language models (LVLMs) have…

Machine Learning · Computer Science 2025-10-13 Aneesh Komanduri , Karuna Bhaila , Xintao Wu

Though Multi-modal Large Language Models (MLLMs) have recently achieved significant progress, they often struggle to understand diverse and complicated inter-object relations. Specifically, the lack of large-scale and high-quality relation…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Jiahao Nie , Gongjie Zhang , Wenbin An , Yun Xing , Yap-Peng Tan , Alex C. Kot , Shijian Lu

Multimodal reasoning, which integrates language and visual cues into problem solving and decision making, is a fundamental aspect of human intelligence and a crucial step toward artificial general intelligence. However, the evaluation of…

Large vision-language models (LVLMs) demonstrate strong performance in dermatology; however, evaluating diagnostic reasoning for rare conditions remains largely unexplored. Existing benchmarks focus on common diseases and assess only final…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Yang Liu , Jiyao Yang , Hongjin Zhao , Xiaoyong Li , Yanzhe Ji , Xingjian Li , Runmin Jiang , Tianyang Wang , Saeed Anwar , Dongwoo Kim , Yue Yao , Zhenyue Qin , Min Xu

Across medical specialties, clinical practice is anchored in evidence-based guidelines that codify best studied diagnostic and treatment pathways. These pathways routinely fall short for the long tail of real-world care not covered by…

Large Language Models (LLMs) and causal learning each hold strong potential for clinical decision making (CDM). However, their synergy remains poorly understood, largely due to the lack of systematic benchmarks evaluating their integration…

Machine Learning · Computer Science 2025-11-14 Linna Wang , Zhixuan You , Qihui Zhang , Jiunan Wen , Ji Shi , Yimin Chen , Yusen Wang , Fanqi Ding , Ziliang Feng , Li Lu

Large language models (LLMs) have recently demonstrated impressive capabilities across a range of reasoning and generation tasks. However, research studies have shown that LLMs lack the ability to identify causal relationships, a…

Machine Learning · Computer Science 2025-11-21 Juncheng Dong , Yiling Liu , Ahmed Aloui , Vahid Tarokh , David Carlson

Rare diseases affect hundreds of millions worldwide, yet diagnosis often spans years. Convectional pipelines decouple noisy evidence extraction from downstream inferential diagnosis, and general/medical large language models (LLMs) face…

Vision-threatening eye diseases pose a major global health burden, with timely diagnosis limited by workforce shortages and restricted access to specialized care. While multimodal large language models (MLLMs) show promise for medical image…

The rising prevalence of eye diseases poses a growing public health burden. Large language models (LLMs) offer a promising path to reduce documentation workload and support clinical decision-making. However, few have been tailored for…

Large language models (LLMs) have been widely adopted across diverse domains of software engineering, such as code generation, program repair, and vulnerability detection. These applications require understanding beyond surface-level code…

Software Engineering · Computer Science 2026-01-21 Danning Xie , Mingwei Zheng , Xuwei Liu , Jiannan Wang , Chengpeng Wang , Lin Tan , Xiangyu Zhang